369:
760:
832:, from 1795 on Director of the Medical Bureau of the Batavian Republic, and inspector-general of the French Imperial Military Health-Service in 1811, became a leading expert in the fight against hospital-gangrene and its prevention. He wrote a treatise on gangrene in 1814 in which he meticulously analyzed and explained the causes of this dreadful disease, which he was convinced was contagious. He completed his entry with a thorough evaluation of all possible and well experienced sanitary regulations. His work was very well received and was instrumental in convincing most later authors that gangrene was a contagious disease.
475:
502:, for example), which cause tissue to swell and emit a foul odor. Wet gangrene usually develops rapidly due to blockage of venous (mainly) or arterial blood flow. The affected part is saturated with stagnant blood, which promotes the rapid growth of bacteria. The toxic products formed by bacteria are absorbed, causing systemic manifestation of sepsis and finally death. The affected part is edematous, soft, putrid, rotten, and dark.
47:
2260:
562:. These environmental bacteria may enter the muscle through a wound and subsequently proliferate in necrotic tissue and secrete powerful toxins that destroy nearby tissue, generating gas at the same time. A gas composition of 5.9% hydrogen, 3.4% carbon dioxide, 74.5% nitrogen, and 16.1% oxygen was reported in one clinical case.
666:
and antibiotics. Since gangrene is associated with periodic pain caused by too little blood flow, pain management is important so patients can continue doing exercises that promote circulation. Pain management medications can include opioids and opioid-like analgesics. Since gangrene is a result of
585:
is a rare infection that spreads deep into the body along tissue planes. It is categorized into four subtypes, with the first two being the most common. Type 1 requires an infection with an anaerobe and a species in the
Enterobacteriaceae family, while type 2 is characterized by infection with
1402:
Gerhard-Herman, MD; Gornik, HL; Barrett, C; Barshes, NR; Corriere, MA; Drachman, DE; Fleisher, LA; Fowkes, FG; Hamburg, NM; Kinlay, S; Lookstein, R; Misra, S; Mureebe, L; Olin, JW; Patel, RA; Regensteiner, JG; Schanzer, A; Shishehbor, MH; Stewart, KJ; Treat-Jacobson, D; Walsh, ME (2017).
708:
Dead tissue alone does not require debridement, and in some cases, such as dry gangrene, the affected part falls off (autoamputates), making surgical removal unnecessary. Waiting for autoamputation, however, may cause health complications as well as decreased quality of life.
782:
to prevent or arrest necrotic spread, as some species of maggots consume only dead flesh, leaving nearby living tissue unaffected. This practice largely died out after the introduction of antibiotics to the range of treatments for wounds. In recent times, however,
465:
is a risk factor for peripheral vascular disease, thus for dry gangrene, but also a risk factor for wet gangrene, particularly in patients with poorly controlled blood sugar levels, as elevated serum glucose creates a favorable environment for bacterial infection.
687:
are often a critical component of its treatment. The life-threatening nature of gangrene requires treatment with intravenous antibiotics in an inpatient setting. Antibiotics alone are not effective because they may not penetrate infected tissues sufficiently.
541:, or various nonclostridial species. Infection spreads rapidly as the gases produced by the bacteria expand and infiltrate healthy tissue in the vicinity. Because of its ability to quickly spread to surrounding tissues, gas gangrene should be treated as a
431:
and bacteria fail to survive. The affected part is dry, shrunken, and dark reddish-black. The line of separation usually brings about complete separation, with eventual falling off of the gangrenous tissue if it is not removed surgically, a process called
2149:"Verhandeling ter beantwoording der vrage: Kan de gesteldheid en zamenstelling van den dampkring, welke onmiddelijk tot de Hospitaal-versterving (Gangraena NosocomialisZ) aanleiding geeft, door Natuur- of Scheikundige middelen worden ontdekt?"
226:. Symptoms may include a change in skin color to red or black, numbness, swelling, pain, skin breakdown, and coolness. The feet and hands are most commonly affected. If the gangrene is caused by an infectious agent, it may present with a
1360:
Aiello A, Anichini R, Brocco E, Caravaggi C, Chiavetta A, Cioni R, Da Ros R, De Feo ME, Ferraresi R, Florio F, Gargiulo M, Galzerano G, Gandini R, Giurato L, Graziani L, Mancini L, Manzi M, Modugno P, Setacci C, Uccioli L (2014).
700:
to hinder the spread of the associated infection. The extent of surgical debridement needed depends on the extent of the gangrene and may be limited to the removal of a finger, toe, or ear, but in severe cases may involve a
1405:"2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines"
2330:
2303:
2288:
455:(via vascular bypass or angioplasty). However, once gangrene has developed, the affected tissues are not salvageable. Because dry gangrene is not accompanied by infection, it is not as
696:
Surgical removal of all dead tissue, however, is the mainstay of treatment for gangrene. Often, gangrene is associated with underlying infection, thus the gangrenous tissue must be
847:
solutions on infected wounds to reduce the incidence and virulence of "poisoned miasma". Copies of his book were issued to Union surgeons to encourage the use of his methods.
1363:"Treatment of peripheral arterial disease in diabetes: a consensus of the Italian Societies of Diabetes (SID, AMD), Radiology (SIRM) and Vascular Endovascular Surgery (SICVE)"
741:
treatment is used to treat gas gangrene. It increases pressure and oxygen content to allow blood to carry more oxygen to inhibit anaerobic organism growth and reproduction.
1931:
Liu R, Li L, Yang M, Boden G, Yang G (2013). "Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers".
459:
as gas gangrene or wet gangrene, both of which have a risk of sepsis. Over time, dry gangrene may develop into wet gangrene if an infection develops in the dead tissues.
372:
An illustration showing four different stages of gangrene, including one (Fig. 4 top right) caused by an obstacle to the return of the venous blood due to heart disease.
486:(compared to dry gangrene) due to sepsis resulting from the free communication between infected fluid and circulatory fluid. In wet gangrene, the tissue is infected by
719:
Ischemic disease of the legs is the most common reason for amputations. In about a quarter of these cases, the other side requires amputation in the next three years.
843:
was 45%. Goldsmith's method, which he applied to over 330 cases, yielded a mortality under 3%." Goldsmith advocated the use of debridement and topical and injected
3035:
839:
during the
American Civil War, meticulously studied hospital gangrene and developed a revolutionary treatment regimen. The cumulative Civil War hospital gangrene
505:
Because of the high mortality associated with infected gangrene (about 80% without treatment and 20% with treatment), an emergency salvage amputation, such as a
427:. As a result, people with atherosclerosis, high cholesterol, diabetes and smokers commonly have dry gangrene. The limited oxygen in the ischemic limb limits
3305:
376:
Symptoms may include a change in skin color to red or black, numbness, pain, skin breakdown, and coolness. The feet and hands are most commonly involved.
2471:
3028:
2046:
4020:
3607:
3115:
415:
is used only when referring to a limb or to the gut (in other locations, this same type of necrosis is called an infarction, such as
712:
After the gangrene is treated with debridement and antibiotics, the underlying cause can be treated. In the case of gangrene due to
509:, is often needed to limit systemic effects of the infection. Such an amputation can be converted to a formal amputation, such as a
411:, where the blood supply is inadequate to keep tissue viable. It is not a disease itself, but a symptom of other diseases. The term
3125:
3021:
3400:
2464:
67:
759:
4061:
3339:
1758:
368:
3518:
3080:
1200:
Korzon-Burakowska, A; Dziemidok, P (December 2011). "Diabetic foot-the need for comprehensive multidisciplinary approach".
3968:
3313:
2611:
534:
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3500:
2922:
1461:
1236:
318:
123:
2001:
3926:
3664:
3523:
3426:
2457:
1263:
3334:
3321:
2890:
608:
3832:
3408:
2164:"Gangrene therapy and antisepsis before lister: the civil war contributions of Middleton Goldsmith of Louisville"
298:
3573:
3395:
3349:
3260:
3250:
4071:
3677:
3597:
3543:
2083:
3985:
3513:
3354:
3138:
2009:
1479:"Necrotising fasciitis in the central part of the body: diagnosis, management and review of the literature"
1695:
4005:
3626:
3538:
2134:
Teun van
Heiningen, "Sebald Justinus Brugmans' strijd tegen de hospitaalversterving", Leiden University,
385:
242:
143:
4025:
3827:
2226:
3553:
3329:
2264:
2110:
716:, revascularization can be performed to treat the underlying peripheral underlateral artery disease.
420:
357:
55:
20:
4076:
3822:
3528:
3495:
3205:
3120:
3071:
2349:
825:
336:
to treat any infection, and efforts to address the underlying cause. Surgical efforts may include
3953:
3753:
3490:
3465:
3385:
2997:
2604:
2508:
1774:
Levenson, RB; Singh, AK; Novelline, RA (March–April 2008). "Fournier gangrene: role of imaging".
1592:
723:
492:
92:
3533:
3485:
3475:
3470:
3359:
3044:
713:
588:
2400:
2042:"A systematic review of maggot debridement therapy for chronically infected wounds and ulcers"
1910:
1748:
3980:
3958:
3871:
3184:
2785:
2753:
2556:
2297:
1817:
Warkentin, TE (August 2010). "Agents for the treatment of heparin-induced thrombocytopenia".
592:, a Gram-positive cocci bacteria, and thus is also known as hemolytic streptococcal gangrene.
582:
510:
506:
416:
322:
302:
294:
171:
127:
2148:
552:-producing clostridial species, which are mostly found in soil, and other anaerobes such as
527:
Gas gangrene is a bacterial infection that produces gas within tissues. It can be caused by
4015:
3684:
3673:
3300:
3290:
3090:
2955:
2950:
2907:
2857:
2748:
2727:
2023:
401:
2426:
2423:
1893:
8:
3897:
3892:
3802:
3728:
3718:
3692:
3688:
3563:
3369:
3280:
3052:
2912:
2880:
2722:
2690:
2561:
2546:
2518:
2420:
2417:
2414:
2411:
2334:
819:
798:
779:
748:
738:
619:
498:
487:
424:
2210:
1721:
3948:
3859:
3270:
3255:
3245:
2940:
2932:
2917:
2885:
2865:
2773:
2597:
2566:
2193:
1799:
1617:
1563:
1538:
1516:
1503:
1478:
1429:
1404:
1337:
1302:
1177:
1152:
1125:
1100:
840:
822:
died of gangrene in his leg on 1 September 1715, four days prior to his 77th birthday.
808:
663:
598:
is a gangrene of the face most often found in Africa, Southeast Asia and South
America.
290:
82:
2343:
2339:
1870:
1853:
4066:
4051:
3973:
3653:
3364:
2977:
2360:
2185:
2065:
1983:
1966:
Shi, Eric; Shofler, David (2014). "Maggot debridement therapy: A systematic review".
1948:
1875:
1834:
1791:
1754:
1652:
1609:
1568:
1508:
1494:
1457:
1434:
1384:
1342:
1324:
1259:
1232:
1209:
1182:
1130:
829:
672:
662:
Medications may include pain management, medications that promote circulation in the
601:
542:
462:
452:
178:
62:
2197:
1621:
1073:
1048:
4010:
3931:
3745:
3713:
2897:
2763:
2649:
2513:
2175:
2055:
1979:
1975:
1940:
1865:
1826:
1803:
1783:
1636:
1601:
1558:
1554:
1550:
1520:
1498:
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1424:
1416:
1374:
1332:
1314:
1172:
1168:
1164:
1120:
1112:
912:
630:
408:
282:
159:
2135:
1670:
3904:
3792:
3616:
3548:
3455:
3275:
3154:
2965:
2945:
2571:
2354:
1944:
1420:
1379:
1362:
1253:
1116:
980:
727:
634:
623:
326:
2060:
2041:
801:
contracted gangrene in
January 1687 when, while conducting a performance of his
482:
Wet, or infected, gangrene is characterized by thriving bacteria and has a poor
325:. The diagnosis of gangrene is based on symptoms and supported by tests such as
4030:
3909:
3812:
3642:
3508:
3450:
3435:
3295:
3226:
2987:
2982:
2902:
2541:
2503:
2365:
2180:
2163:
870:
784:
604:
is a type of necrotizing fasciitis that usually affects the genitals and groin.
595:
448:
433:
349:
345:
2324:
2320:
2316:
1830:
87:
Change in skin color to red or black, numbness, pain, skin breakdown, coolness
4045:
3990:
3807:
3703:
3659:
3344:
3143:
3101:
2870:
2683:
1328:
795:
744:
680:
676:
559:
286:
183:
Based on symptom, With medical imaging used to identify the underlying cause.
2312:
671:, circulatory system management is important. These medications can include
565:
Gas gangrene can cause necrosis, gas production, and sepsis. Progression to
456:
3995:
3921:
3817:
3589:
3480:
3460:
3265:
3179:
2972:
2802:
2778:
2768:
2673:
2661:
2654:
2449:
2189:
2069:
1987:
1952:
1879:
1838:
1795:
1613:
1572:
1512:
1438:
1388:
1346:
1213:
1186:
1134:
879:
811:). The disease spread to his leg, but the composer refused to have his toe
570:
522:
474:
428:
314:
310:
306:
270:
250:
151:
119:
115:
111:
1656:
1151:
Yang, Z; Hu, J; Qu, Y; Sun, F; Leng, X; Li, H; Zhan, S (3 December 2015).
1013:
722:
Angioplasty should be considered if severe blockage in lower leg vessels (
4000:
3708:
3602:
3568:
3558:
3390:
3200:
3170:
3013:
2960:
2826:
2707:
2702:
2678:
2395:
1787:
1319:
697:
684:
554:
529:
353:
337:
333:
134:
1605:
3888:
3883:
3211:
3161:
3134:
2992:
2835:
2831:
2807:
2736:
2717:
2530:
2484:
2437:
2432:
943:
836:
812:
763:
702:
612:
566:
341:
278:
254:
155:
101:
2280:
3878:
3723:
3647:
3593:
3061:
2847:
2790:
2712:
2639:
2620:
2480:
2406:
2371:
1898:
1303:"Autoamputation of diabetic toe with dry gangrene: a myth or a fact?"
873:
856:
807:, he stabbed his own toe with his pointed staff (which was used as a
483:
444:
266:
262:
196:
167:
2245:
Liddell & Scott's
Lexicon, Oxford University Press, 1963 edition
766:
Private Milton E. Wallen lies in bed with a gangrenous amputated arm
384:
Gangrene is caused by a critically insufficient blood supply (e.g.,
3914:
3777:
3772:
3621:
3110:
3085:
3002:
2797:
2743:
2666:
2644:
2492:
788:
787:
has regained some credibility and is sometimes employed with great
668:
549:
440:
405:
389:
258:
238:
223:
219:
163:
139:
75:
2376:
1720:
Puvanendran, Rukshini; Chan Meng Huey, Jason; Pasupathy, Shanker.
1401:
3943:
3854:
3782:
3698:
3285:
2875:
2840:
2820:
2697:
2634:
1477:
Vayvada, H; Demirdover, C; Menderes, A; Karaca, C (August 2013).
844:
803:
274:
246:
147:
71:
451:
rather than gangrene are present, the process can be treated by
3938:
2307:
2292:
2259:
2040:
Sun, Xinjuan; Jiang, Kechun; Chen, Jingan; et al. (2014).
1854:"Evidence-based antibiotic therapy of diabetic foot infections"
1476:
835:
John M. Trombold wrote: "Middleton
Goldsmith, a surgeon in the
775:
231:
97:
46:
1719:
3797:
2227:"Hospital Gangrene During The Civil War – Civil War Medicine"
1359:
1307:
Diabetes, Metabolic
Syndrome and Obesity: Targets and Therapy
860:
646:
Treatment varies based on the severity and type of gangrene.
360:
may be useful. How commonly the condition occurs is unknown.
227:
2589:
654:
Exercises such as walking and massage therapy may be tried.
3866:
3787:
1746:
1101:"Management of lower extremity peripheral arterial disease"
815:, which eventually led to his death in March of that year.
1199:
771:
332:
Treatment may involve surgery to remove the dead tissue,
16:
Type of tissue death by infection or lack of blood supply
1747:
Sivapathasundharam, B.; Rajendran, Arya (30 June 2012).
1105:
751:
have successfully altered gangrene and ulcer prognosis.
1911:"Angioplasty and stent placement – peripheral arteries"
1258:(7th ed.). Elsevier Health Sciences. p. 124.
1773:
2212:
A report on hospital gangrene, erysipelas and pyaemia
1586:
Sakurai, J.; Nagahama, M.; Oda, M. (November 2004). "
2270:
348:. Efforts to treat the underlying cause may include
1590:alpha-toxin: characterization and mode of action".
1634:
1585:
683:. As infection is often associated with gangrene,
1202:Annals of Agricultural and Environmental Medicine
4043:
1696:"For Clinicians: Type II Necrotizing Fasciitis"
1099:Gardner, AW; Afaq, A (November–December 2008).
54:Dry gangrene affecting the toes as a result of
2039:
1930:
778:were commonly used to treat chronic wounds or
3029:
2605:
2465:
1639:, Wu MH (December 1995). "Gas composition in
1008:
1006:
1004:
1002:
2479:
2047:International Journal of Infectious Diseases
1819:Hematology/Oncology Clinics of North America
1539:"Type of incision for below knee amputation"
975:
973:
971:
969:
967:
965:
907:
905:
903:
901:
899:
897:
895:
2161:
2151:. J. van der Heij – via Google Books.
1645:Journal of the Formosan Medical Association
1543:The Cochrane Database of Systematic Reviews
1157:The Cochrane Database of Systematic Reviews
1150:
1098:
1043:
1041:
1039:
1037:
1035:
864:
4021:Recurrent toxin-mediated perineal erythema
3307:Mycobacterium avium–intracellulare complex
3043:
3036:
3022:
2612:
2598:
2472:
2458:
2147:Brugmans, Sebald Justinus (May 24, 1814).
2002:"Product Classification: Maggots, Medical"
1965:
1532:
1530:
1255:Underwood's Pathology: A Clinical Approach
1146:
1144:
999:
45:
3116:Cutaneous group B streptococcal infection
2179:
2108:
2059:
1869:
1851:
1816:
1753:. Elsevier Health Sciences. p. 333.
1562:
1502:
1428:
1378:
1336:
1318:
1176:
1153:"Interventions for treating gas gangrene"
1124:
962:
892:
2146:
1536:
1300:
1032:
938:
936:
934:
758:
473:
367:
1579:
1527:
1229:Gangrene Management: Today and Tomorrow
1141:
4044:
2090:. Utah Symphony Orchestra. August 2010
1451:
607:Venous limb gangrene may be caused by
447:. If ischemia is detected early, when
439:Dry gangrene is the result of chronic
388:) or infection. It is associated with
3340:Rapid growing mycobacterium infection
3017:
2593:
2453:
1296:
1294:
1292:
1290:
1288:
1286:
1284:
1282:
1251:
1226:
931:
791:in cases of chronic tissue necrosis.
363:
3519:Human granulocytotropic anaplasmosis
3081:Staphylococcal scalded skin syndrome
2109:Laurenson, John (21 November 2015).
1968:British Journal of Community Nursing
1675:The Lecturio Medical Concept Library
548:Gas gangrene is caused by bacterial
3969:Chronic undermining burrowing ulcer
2084:"Music Trivia – The Death of Lully"
1959:
1750:Shafer's Textbook of Oral Pathology
1537:Tisi, PV; Than, MM (8 April 2014).
13:
2923:Fluorescence in situ hybridization
2224:
1894:Amputations of the Lower Extremity
1279:
14:
4088:
3927:Superficial pustular folliculitis
3524:Human monocytotropic ehrlichiosis
2252:
1301:Al Wahbi, Abdullah (2018-06-01).
3335:Primary inoculation tuberculosis
2891:Oral and maxillofacial pathology
2258:
2111:"The strange death of Louis XIV"
1495:10.1111/j.1742-481x.2012.01006.x
609:Heparin-induced thrombocytopenia
419:). Dry gangrene is often due to
3833:Gram-negative toe web infection
3409:Group JK corynebacterium sepsis
2239:
2218:
2204:
2155:
2140:
2128:
2102:
2076:
2033:
2016:
1994:
1924:
1903:
1886:
1845:
1810:
1767:
1740:
1713:
1688:
1663:
1628:
1470:
1445:
1395:
1353:
1245:
1220:
516:
511:below- or above-knee amputation
469:
395:
392:and long-term tobacco smoking.
299:Group B streptococcal infection
3574:Ehrlichiosis ewingii infection
3396:Cutaneous diphtheria infection
3350:Tuberculosis cutis orificialis
3261:Borderline tuberculoid leprosy
3251:Borderline lepromatous leprosy
1980:10.12968/bjcn.2014.19.Sup12.S6
1555:10.1002/14651858.CD003749.pub3
1193:
1169:10.1002/14651858.CD010577.pub2
1092:
1066:
633:may result in gangrene of the
622:may result in gangrene of the
576:
1:
3598:Primary gonococcal dermatitis
3544:Flinders Island spotted fever
2619:
1871:10.1016/s0928-8244(99)00143-1
885:
859:of gangrene derives from the
657:
4062:Symptoms and signs: Vascular
3986:Blistering distal dactylitis
3514:Rocky Mountain spotted fever
3402:Arcanobacterium haemolyticum
3355:Tuberculosis verrucosa cutis
3139:Chronic recurrent erysipelas
2010:Food and Drug Administration
1945:10.1016/j.mayocp.2012.10.021
1858:FEMS Immunol. Med. Microbiol
1726:national library of medicine
1421:10.1161/CIR.0000000000000471
1380:10.1016/j.numecd.2013.12.007
1117:10.1097/HCR.0b013e31818c3b96
874:
850:
649:
641:
7:
4006:Blastomycosis-like pyoderma
3627:Chromobacteriosis infection
3539:Mediterranean spotted fever
2061:10.1016/j.ijid.2014.03.1397
1852:Lipsky BA (December 1999).
1635:Chi CH, Chen KW, Huang JJ,
1483:International Wound Journal
386:peripheral vascular disease
243:peripheral arterial disease
191:Depends on underlying cause
144:peripheral arterial disease
10:
4093:
4026:Tick-borne lymphadenopathy
3828:Gram-negative folliculitis
2181:10.1177/000313481107700924
878:(γάγγραινα), which means "
754:
691:
520:
400:Dry gangrene is a form of
305:. It can be classified as
18:
4057:Health effects of tobacco
3845:
3765:
3744:
3635:
3582:
3443:
3434:
3425:
3378:
3330:Papulonecrotic tuberculid
3315:Mycobacterium haemophilum
3234:
3225:
3193:
3168:
3152:
3099:
3069:
3060:
3051:
2931:
2856:
2627:
2529:
2491:
2386:
2274:
2136:URN:NBN:NL:UI:10-1-112565
2024:"FDA CDRH 510(k) summary"
1831:10.1016/j.hoc.2010.05.009
1367:Nutr Metab Cardiovasc Dis
739:Hyperbaric oxygen therapy
478:Wet gangrene of the foot.
421:peripheral artery disease
379:
358:hyperbaric oxygen therapy
205:
195:
187:
177:
133:
107:
91:
81:
61:
56:peripheral artery disease
53:
44:
36:
31:
21:Gangrene (disambiguation)
3823:Lymphogranuloma venereum
3529:Flea-borne spotted fever
3502:Rickettsia aeschlimannii
3496:American tick bite fever
3206:Erysipeloid of Rosenbach
3121:Streptococcal intertrigo
1643:septicum gas gangrene".
826:Sebald Justinus Brugmans
733:
3954:Trichomycosis axillaris
3491:African tick bite fever
3466:North Asian tick typhus
3386:Cutaneous actinomycosis
2998:Microbiological culture
2628:Principles of pathology
1722:"Necrotizing fasciitis"
1593:Journal of Biochemistry
1588:Clostridium perfringens
493:Clostridium perfringens
3666:Haemophilus influenzae
3610:Pasteurella hemolytica
3534:Japanese spotted fever
3486:Bacillary angiomatosis
3476:Flying squirrel typhus
3471:Queensland tick typhus
3360:Tuberculous cellulitis
3323:Mycobacterium kansasii
3045:Bacterial skin disease
865:
767:
714:critical limb ischemia
589:Streptococcus pyogenes
479:
373:
3981:Elephantiasis nostras
3959:Necrotizing fasciitis
3872:Hospital furunculosis
3554:Brill–Zinsser disease
3185:Dermatitis gangrenosa
2961:Diagnostic immunology
2786:Programmed cell death
2754:Liquefactive necrosis
2088:The Musician's Lounge
1452:Nather, Aziz (2013).
1252:Cross, Simon (2018).
1227:Smith, Tyler (2015).
762:
730:) leads to gangrene.
583:Necrotizing fasciitis
573:is often very rapid.
507:guillotine amputation
477:
417:myocardial infarction
371:
323:necrotizing fasciitis
295:meningococcal disease
237:Risk factors include
128:necrotizing fasciitis
4072:Causes of amputation
4016:Chronic lymphangitis
3685:Hot tub folliculitis
3674:Pseudomonal pyoderma
3301:Miliary tuberculosis
3291:Lichen scrofulosorum
3091:Toxic shock syndrome
2956:Medical microbiology
2951:Transfusion medicine
2908:Immunohistochemistry
2858:Anatomical pathology
2749:Coagulative necrosis
2267:at Wikimedia Commons
2162:Trombold JM (2011).
1788:10.1148/rg.282075048
1456:. World Scientific.
1320:10.2147/DMSO.S164199
1074:"Gangrene Diagnosis"
1049:"Gangrene Treatment"
745:Regenerative medical
423:, but can be due to
402:coagulative necrosis
356:. In certain cases,
224:lack of blood supply
19:For other uses, see
3905:Acute lymphadenitis
3898:Perianal cellulitis
3893:Pyogenic paronychia
3803:Chlamydia infection
3719:Granuloma inguinale
3693:Green nail syndrome
3689:Ecthyma gangrenosum
3564:Cat-scratch disease
3370:Tuberculoid leprosy
3281:Lepromatous leprosy
3128:Streptococcus iniae
2913:Electron microscopy
2881:Molecular pathology
2759:Gangrenous necrosis
2691:Cellular adaptation
2225:Watson, Dr. Scott.
913:"Gangrene Symptoms"
799:Jean-Baptiste Lully
749:stem-cell therapies
620:mesenteric ischemia
499:Bacillus fusiformis
425:acute limb ischemia
40:Gangrenous necrosis
3949:Pitted keratolysis
3860:Periapical abscess
3271:Erythema induratum
3256:Borderline leprosy
3246:Aquarium granuloma
2941:Clinical chemistry
2933:Clinical pathology
2918:Immunofluorescence
2886:Forensic pathology
2866:Surgical pathology
2774:Fibrinoid necrosis
2387:External resources
770:As early as 1028,
768:
664:circulatory system
480:
374:
364:Signs and symptoms
303:Raynaud's syndrome
291:radiation injuries
172:Raynaud's syndrome
68:Infectious disease
4039:
4038:
3974:Fournier gangrene
3841:
3840:
3740:
3739:
3681:hot-foot syndrome
3654:Vibrio vulnificus
3421:
3420:
3417:
3416:
3365:Tuberculous gumma
3221:
3220:
3011:
3010:
2978:Mass spectrometry
2587:
2586:
2447:
2446:
2263:Media related to
1760:978-81-312-3800-4
1606:10.1093/jb/mvh161
1454:The diabetic foot
1231:. Hayle Medical.
1080:. 13 October 2015
1020:. 13 October 2015
987:. 13 October 2015
981:"Gangrene Causes"
919:. 13 October 2015
830:Leyden University
673:antiplatelet drug
602:Fournier gangrene
543:medical emergency
463:Diabetes mellitus
453:revascularization
404:that develops in
319:internal gangrene
213:
212:
179:Diagnostic method
26:Medical condition
4084:
4011:Bullous impetigo
3932:Sycosis vulgaris
3746:Campylobacterota
3695:
3441:
3440:
3432:
3431:
3232:
3231:
3067:
3066:
3058:
3057:
3038:
3031:
3024:
3015:
3014:
2898:Gross processing
2764:Caseous necrosis
2614:
2607:
2600:
2591:
2590:
2474:
2467:
2460:
2451:
2450:
2272:
2271:
2262:
2246:
2243:
2237:
2236:
2234:
2233:
2222:
2216:
2208:
2202:
2201:
2183:
2159:
2153:
2152:
2144:
2138:
2132:
2126:
2125:
2123:
2121:
2106:
2100:
2099:
2097:
2095:
2080:
2074:
2073:
2063:
2037:
2031:
2030:
2028:
2020:
2014:
2013:
1998:
1992:
1991:
1963:
1957:
1956:
1928:
1922:
1921:
1919:
1917:
1907:
1901:
1890:
1884:
1883:
1873:
1849:
1843:
1842:
1814:
1808:
1807:
1771:
1765:
1764:
1744:
1738:
1737:
1735:
1733:
1717:
1711:
1710:
1708:
1707:
1692:
1686:
1685:
1683:
1681:
1667:
1661:
1660:
1632:
1626:
1625:
1583:
1577:
1576:
1566:
1534:
1525:
1524:
1506:
1474:
1468:
1467:
1449:
1443:
1442:
1432:
1399:
1393:
1392:
1382:
1357:
1351:
1350:
1340:
1322:
1298:
1277:
1276:
1274:
1272:
1249:
1243:
1242:
1224:
1218:
1217:
1197:
1191:
1190:
1180:
1163:(12): CD010577.
1148:
1139:
1138:
1128:
1096:
1090:
1089:
1087:
1085:
1070:
1064:
1063:
1061:
1059:
1045:
1030:
1029:
1027:
1025:
1010:
997:
996:
994:
992:
977:
960:
959:
957:
955:
940:
929:
928:
926:
924:
909:
877:
868:
796:Baroque composer
631:ischemic colitis
533:, most commonly
490:microorganisms (
344:, or the use of
49:
29:
28:
4092:
4091:
4087:
4086:
4085:
4083:
4082:
4081:
4077:Causes of death
4042:
4041:
4040:
4035:
3847:
3837:
3761:
3736:
3672:
3631:
3617:Meningococcemia
3578:
3549:Verruga peruana
3456:Epidemic typhus
3413:
3374:
3276:Histoid leprosy
3237:
3217:
3189:
3164:
3155:Corynebacterium
3148:
3095:
3047:
3042:
3012:
3007:
2966:Immunopathology
2946:Hematopathology
2927:
2852:
2623:
2618:
2588:
2583:
2525:
2519:Small intestine
2514:Large intestine
2487:
2478:
2448:
2443:
2442:
2427:article/2051157
2424:article/2028899
2382:
2381:
2283:
2255:
2250:
2249:
2244:
2240:
2231:
2229:
2223:
2219:
2209:
2205:
2160:
2156:
2145:
2141:
2133:
2129:
2119:
2117:
2107:
2103:
2093:
2091:
2082:
2081:
2077:
2038:
2034:
2026:
2022:
2021:
2017:
2000:
1999:
1995:
1964:
1960:
1933:Mayo Clin. Proc
1929:
1925:
1915:
1913:
1909:
1908:
1904:
1891:
1887:
1864:(3–4): 267–76.
1850:
1846:
1815:
1811:
1772:
1768:
1761:
1745:
1741:
1731:
1729:
1718:
1714:
1705:
1703:
1694:
1693:
1689:
1679:
1677:
1669:
1668:
1664:
1633:
1629:
1584:
1580:
1549:(4): CD003749.
1535:
1528:
1475:
1471:
1464:
1450:
1446:
1415:(12): e726–79.
1400:
1396:
1358:
1354:
1299:
1280:
1270:
1268:
1266:
1250:
1246:
1239:
1225:
1221:
1198:
1194:
1149:
1142:
1097:
1093:
1083:
1081:
1072:
1071:
1067:
1057:
1055:
1047:
1046:
1033:
1023:
1021:
1012:
1011:
1000:
990:
988:
979:
978:
963:
953:
951:
950:. 12 March 2014
942:
941:
932:
922:
920:
911:
910:
893:
888:
853:
828:, Professor at
757:
747:treatments and
736:
728:peroneal artery
703:limb amputation
694:
660:
652:
644:
635:large intestine
624:small intestine
579:
525:
519:
472:
449:ischemic wounds
398:
382:
366:
327:medical imaging
27:
24:
17:
12:
11:
5:
4090:
4080:
4079:
4074:
4069:
4064:
4059:
4054:
4037:
4036:
4034:
4033:
4031:Tropical ulcer
4028:
4023:
4018:
4013:
4008:
4003:
3998:
3993:
3988:
3983:
3978:
3977:
3976:
3971:
3961:
3956:
3951:
3946:
3941:
3936:
3935:
3934:
3929:
3918:
3917:
3912:
3910:Pilonidal cyst
3907:
3902:
3901:
3900:
3895:
3881:
3876:
3875:
3874:
3864:
3863:
3862:
3851:
3849:
3843:
3842:
3839:
3838:
3836:
3835:
3830:
3825:
3820:
3815:
3813:Rat-bite fever
3810:
3805:
3800:
3795:
3790:
3785:
3780:
3775:
3769:
3767:
3763:
3762:
3760:
3759:
3750:
3748:
3742:
3741:
3738:
3737:
3735:
3734:
3726:
3721:
3716:
3711:
3706:
3701:
3696:
3670:
3662:
3657:
3650:
3645:
3643:Pasteurellosis
3639:
3637:
3633:
3632:
3630:
3629:
3624:
3619:
3614:
3605:
3600:
3586:
3584:
3580:
3579:
3577:
3576:
3571:
3566:
3561:
3556:
3551:
3546:
3541:
3536:
3531:
3526:
3521:
3516:
3511:
3509:Rickettsialpox
3506:
3498:
3493:
3488:
3483:
3478:
3473:
3468:
3463:
3458:
3453:
3451:Endemic typhus
3447:
3445:
3438:
3436:Pseudomonadota
3429:
3423:
3422:
3419:
3418:
3415:
3414:
3412:
3411:
3406:
3398:
3393:
3388:
3382:
3380:
3376:
3375:
3373:
3372:
3367:
3362:
3357:
3352:
3347:
3342:
3337:
3332:
3327:
3319:
3311:
3303:
3298:
3296:Lupus vulgaris
3293:
3288:
3283:
3278:
3273:
3268:
3263:
3258:
3253:
3248:
3242:
3240:
3236:Mycobacterium-
3229:
3227:Actinomycetota
3223:
3222:
3219:
3218:
3216:
3215:
3208:
3203:
3197:
3195:
3191:
3190:
3188:
3187:
3182:
3176:
3174:
3166:
3165:
3160:
3158:
3150:
3149:
3147:
3146:
3141:
3132:
3123:
3118:
3113:
3107:
3105:
3097:
3096:
3094:
3093:
3088:
3083:
3077:
3075:
3072:Staphylococcus
3064:
3055:
3049:
3048:
3041:
3040:
3033:
3026:
3018:
3009:
3008:
3006:
3005:
3000:
2995:
2990:
2988:Flow cytometry
2985:
2983:Chromatography
2980:
2975:
2969:
2968:
2963:
2958:
2953:
2948:
2943:
2937:
2935:
2929:
2928:
2926:
2925:
2920:
2915:
2910:
2905:
2903:Histopathology
2900:
2894:
2893:
2888:
2883:
2878:
2873:
2868:
2862:
2860:
2854:
2853:
2851:
2850:
2845:
2844:
2843:
2838:
2829:
2817:
2811:
2810:
2805:
2800:
2795:
2794:
2793:
2783:
2782:
2781:
2776:
2771:
2766:
2761:
2756:
2751:
2741:
2739:
2733:
2732:
2731:
2730:
2725:
2715:
2710:
2705:
2700:
2695:
2693:
2687:
2686:
2681:
2676:
2671:
2670:
2669:
2659:
2658:
2657:
2652:
2647:
2642:
2631:
2629:
2625:
2624:
2617:
2616:
2609:
2602:
2594:
2585:
2584:
2582:
2581:
2576:
2575:
2574:
2569:
2564:
2559:
2551:
2550:
2549:
2544:
2535:
2533:
2527:
2526:
2524:
2523:
2522:
2521:
2516:
2511:
2506:
2497:
2495:
2489:
2488:
2477:
2476:
2469:
2462:
2454:
2445:
2444:
2441:
2440:
2429:
2421:article/438994
2418:article/214992
2415:article/782709
2412:article/217943
2403:
2391:
2390:
2388:
2384:
2383:
2380:
2379:
2368:
2357:
2346:
2327:
2300:
2284:
2279:
2278:
2276:
2275:Classification
2269:
2268:
2254:
2253:External links
2251:
2248:
2247:
2238:
2217:
2203:
2174:(9): 1138–43.
2154:
2139:
2127:
2101:
2075:
2032:
2015:
1993:
1958:
1923:
1902:
1885:
1844:
1809:
1766:
1759:
1739:
1712:
1687:
1671:"Gas Gangrene"
1662:
1651:(12): 757–59.
1627:
1578:
1526:
1469:
1463:978-9814417006
1462:
1444:
1394:
1352:
1278:
1264:
1244:
1238:978-1632412232
1237:
1219:
1192:
1140:
1091:
1065:
1031:
998:
961:
930:
890:
889:
887:
884:
852:
849:
785:maggot therapy
756:
753:
735:
732:
693:
690:
659:
656:
651:
648:
643:
640:
639:
638:
627:
616:
605:
599:
593:
578:
575:
558:and anaerobic
539:C. perfringens
521:Main article:
518:
515:
471:
468:
434:autoamputation
397:
394:
381:
378:
365:
362:
350:bypass surgery
346:maggot therapy
211:
210:
207:
203:
202:
199:
193:
192:
189:
185:
184:
181:
175:
174:
137:
131:
130:
109:
105:
104:
95:
89:
88:
85:
79:
78:
65:
59:
58:
51:
50:
42:
41:
38:
34:
33:
25:
15:
9:
6:
4:
3:
2:
4089:
4078:
4075:
4073:
4070:
4068:
4065:
4063:
4060:
4058:
4055:
4053:
4050:
4049:
4047:
4032:
4029:
4027:
4024:
4022:
4019:
4017:
4014:
4012:
4009:
4007:
4004:
4002:
3999:
3997:
3994:
3992:
3991:Botryomycosis
3989:
3987:
3984:
3982:
3979:
3975:
3972:
3970:
3967:
3966:
3965:
3962:
3960:
3957:
3955:
3952:
3950:
3947:
3945:
3942:
3940:
3937:
3933:
3930:
3928:
3925:
3924:
3923:
3920:
3919:
3916:
3913:
3911:
3908:
3906:
3903:
3899:
3896:
3894:
3890:
3887:
3886:
3885:
3882:
3880:
3877:
3873:
3870:
3869:
3868:
3867:Boil/furuncle
3865:
3861:
3858:
3857:
3856:
3853:
3852:
3850:
3844:
3834:
3831:
3829:
3826:
3824:
3821:
3819:
3816:
3814:
3811:
3809:
3808:Leptospirosis
3806:
3804:
3801:
3799:
3796:
3794:
3791:
3789:
3786:
3784:
3781:
3779:
3776:
3774:
3771:
3770:
3768:
3764:
3758:
3756:
3752:
3751:
3749:
3747:
3743:
3733:
3731:
3727:
3725:
3722:
3720:
3717:
3715:
3712:
3710:
3707:
3705:
3704:Salmonellosis
3702:
3700:
3697:
3694:
3690:
3686:
3682:
3680:
3675:
3671:
3669:
3667:
3663:
3661:
3660:Rhinoscleroma
3658:
3656:
3655:
3651:
3649:
3646:
3644:
3641:
3640:
3638:
3634:
3628:
3625:
3623:
3620:
3618:
3615:
3613:
3611:
3606:
3604:
3601:
3599:
3595:
3591:
3588:
3587:
3585:
3581:
3575:
3572:
3570:
3567:
3565:
3562:
3560:
3557:
3555:
3552:
3550:
3547:
3545:
3542:
3540:
3537:
3535:
3532:
3530:
3527:
3525:
3522:
3520:
3517:
3515:
3512:
3510:
3507:
3505:
3503:
3499:
3497:
3494:
3492:
3489:
3487:
3484:
3482:
3479:
3477:
3474:
3472:
3469:
3467:
3464:
3462:
3459:
3457:
3454:
3452:
3449:
3448:
3446:
3442:
3439:
3437:
3433:
3430:
3428:
3424:
3410:
3407:
3405:
3403:
3399:
3397:
3394:
3392:
3389:
3387:
3384:
3383:
3381:
3377:
3371:
3368:
3366:
3363:
3361:
3358:
3356:
3353:
3351:
3348:
3346:
3345:Scrofuloderma
3343:
3341:
3338:
3336:
3333:
3331:
3328:
3326:
3324:
3320:
3318:
3316:
3312:
3310:
3308:
3304:
3302:
3299:
3297:
3294:
3292:
3289:
3287:
3284:
3282:
3279:
3277:
3274:
3272:
3269:
3267:
3264:
3262:
3259:
3257:
3254:
3252:
3249:
3247:
3244:
3243:
3241:
3239:
3233:
3230:
3228:
3224:
3214:
3213:
3209:
3207:
3204:
3202:
3199:
3198:
3196:
3192:
3186:
3183:
3181:
3178:
3177:
3175:
3173:
3172:
3167:
3163:
3159:
3157:
3156:
3151:
3145:
3144:Scarlet fever
3142:
3140:
3136:
3133:
3131:
3129:
3124:
3122:
3119:
3117:
3114:
3112:
3109:
3108:
3106:
3104:
3103:
3102:Streptococcus
3098:
3092:
3089:
3087:
3084:
3082:
3079:
3078:
3076:
3074:
3073:
3068:
3065:
3063:
3059:
3056:
3054:
3050:
3046:
3039:
3034:
3032:
3027:
3025:
3020:
3019:
3016:
3004:
3001:
2999:
2996:
2994:
2991:
2989:
2986:
2984:
2981:
2979:
2976:
2974:
2971:
2970:
2967:
2964:
2962:
2959:
2957:
2954:
2952:
2949:
2947:
2944:
2942:
2939:
2938:
2936:
2934:
2930:
2924:
2921:
2919:
2916:
2914:
2911:
2909:
2906:
2904:
2901:
2899:
2896:
2895:
2892:
2889:
2887:
2884:
2882:
2879:
2877:
2874:
2872:
2871:Cytopathology
2869:
2867:
2864:
2863:
2861:
2859:
2855:
2849:
2846:
2842:
2839:
2837:
2833:
2830:
2828:
2825:
2824:
2823:
2822:
2818:
2816:
2815:Accumulations
2813:
2812:
2809:
2806:
2804:
2801:
2799:
2796:
2792:
2789:
2788:
2787:
2784:
2780:
2777:
2775:
2772:
2770:
2767:
2765:
2762:
2760:
2757:
2755:
2752:
2750:
2747:
2746:
2745:
2742:
2740:
2738:
2735:
2734:
2729:
2726:
2724:
2721:
2720:
2719:
2716:
2714:
2711:
2709:
2706:
2704:
2701:
2699:
2696:
2694:
2692:
2689:
2688:
2685:
2684:Wound healing
2682:
2680:
2677:
2675:
2672:
2668:
2665:
2664:
2663:
2660:
2656:
2653:
2651:
2648:
2646:
2643:
2641:
2638:
2637:
2636:
2633:
2632:
2630:
2626:
2622:
2615:
2610:
2608:
2603:
2601:
2596:
2595:
2592:
2580:
2577:
2573:
2570:
2568:
2565:
2563:
2560:
2558:
2555:
2554:
2552:
2548:
2545:
2543:
2540:
2539:
2537:
2536:
2534:
2532:
2528:
2520:
2517:
2515:
2512:
2510:
2507:
2505:
2502:
2501:
2499:
2498:
2496:
2494:
2490:
2486:
2482:
2475:
2470:
2468:
2463:
2461:
2456:
2455:
2452:
2439:
2435:
2434:
2430:
2428:
2425:
2422:
2419:
2416:
2413:
2409:
2408:
2404:
2402:
2398:
2397:
2393:
2392:
2389:
2385:
2378:
2374:
2373:
2369:
2367:
2363:
2362:
2358:
2356:
2352:
2351:
2347:
2345:
2341:
2337:
2336:
2332:
2328:
2326:
2322:
2318:
2314:
2310:
2309:
2305:
2301:
2299:
2295:
2294:
2290:
2286:
2285:
2282:
2277:
2273:
2266:
2261:
2257:
2256:
2242:
2228:
2221:
2214:
2213:
2207:
2199:
2195:
2191:
2187:
2182:
2177:
2173:
2169:
2165:
2158:
2150:
2143:
2137:
2131:
2116:
2115:The Spectator
2112:
2105:
2089:
2085:
2079:
2071:
2067:
2062:
2057:
2053:
2049:
2048:
2043:
2036:
2025:
2019:
2011:
2007:
2003:
1997:
1989:
1985:
1981:
1977:
1973:
1969:
1962:
1954:
1950:
1946:
1942:
1939:(2): 166–75.
1938:
1934:
1927:
1912:
1906:
1900:
1896:
1895:
1889:
1881:
1877:
1872:
1867:
1863:
1859:
1855:
1848:
1840:
1836:
1832:
1828:
1825:(4): 755–75.
1824:
1820:
1813:
1805:
1801:
1797:
1793:
1789:
1785:
1782:(2): 519–28.
1781:
1777:
1776:Radiographics
1770:
1762:
1756:
1752:
1751:
1743:
1727:
1723:
1716:
1701:
1697:
1691:
1676:
1672:
1666:
1658:
1654:
1650:
1646:
1642:
1638:
1631:
1623:
1619:
1615:
1611:
1607:
1603:
1600:(5): 569–74.
1599:
1595:
1594:
1589:
1582:
1574:
1570:
1565:
1560:
1556:
1552:
1548:
1544:
1540:
1533:
1531:
1522:
1518:
1514:
1510:
1505:
1500:
1496:
1492:
1489:(4): 466–72.
1488:
1484:
1480:
1473:
1465:
1459:
1455:
1448:
1440:
1436:
1431:
1426:
1422:
1418:
1414:
1410:
1406:
1398:
1390:
1386:
1381:
1376:
1373:(4): 355–69.
1372:
1368:
1364:
1356:
1348:
1344:
1339:
1334:
1330:
1326:
1321:
1316:
1312:
1308:
1304:
1297:
1295:
1293:
1291:
1289:
1287:
1285:
1283:
1267:
1265:9780702072109
1261:
1257:
1256:
1248:
1240:
1234:
1230:
1223:
1215:
1211:
1208:(2): 314–17.
1207:
1203:
1196:
1188:
1184:
1179:
1174:
1170:
1166:
1162:
1158:
1154:
1147:
1145:
1136:
1132:
1127:
1122:
1118:
1114:
1111:(6): 349–57.
1110:
1106:
1102:
1095:
1079:
1075:
1069:
1054:
1050:
1044:
1042:
1040:
1038:
1036:
1019:
1015:
1009:
1007:
1005:
1003:
986:
982:
976:
974:
972:
970:
968:
966:
949:
945:
939:
937:
935:
918:
914:
908:
906:
904:
902:
900:
898:
896:
891:
883:
882:of tissues".
881:
876:
872:
869:and from the
867:
862:
858:
848:
846:
842:
838:
833:
831:
827:
823:
821:
816:
814:
810:
806:
805:
800:
797:
792:
790:
786:
781:
777:
773:
765:
761:
752:
750:
746:
742:
740:
731:
729:
725:
720:
717:
715:
710:
706:
704:
699:
689:
686:
682:
681:fibrinolytics
678:
677:anticoagulant
674:
670:
665:
655:
647:
636:
632:
628:
625:
621:
617:
614:
610:
606:
603:
600:
597:
594:
591:
590:
584:
581:
580:
574:
572:
568:
563:
561:
557:
556:
551:
546:
544:
540:
536:
532:
531:
524:
514:
512:
508:
503:
501:
500:
495:
494:
489:
485:
476:
467:
464:
460:
458:
454:
450:
446:
442:
437:
435:
430:
426:
422:
418:
414:
410:
407:
403:
393:
391:
387:
377:
370:
361:
359:
355:
351:
347:
343:
339:
335:
330:
328:
324:
320:
316:
312:
308:
304:
300:
296:
292:
288:
287:hypernatremia
284:
280:
276:
272:
268:
264:
260:
256:
252:
248:
244:
240:
235:
233:
229:
225:
221:
218:is a type of
217:
208:
204:
200:
198:
194:
190:
186:
182:
180:
176:
173:
169:
165:
161:
157:
153:
149:
145:
141:
138:
136:
132:
129:
125:
121:
117:
113:
110:
106:
103:
99:
96:
94:
93:Complications
90:
86:
84:
80:
77:
73:
69:
66:
64:
60:
57:
52:
48:
43:
39:
35:
30:
22:
3996:Malakoplakia
3963:
3922:Folliculitis
3846:Unspecified
3818:Lyme disease
3755:Helicobacter
3754:
3729:
3678:
3665:
3652:
3609:
3590:Gonococcemia
3501:
3481:Trench fever
3461:Scrub typhus
3401:
3322:
3314:
3306:
3266:Buruli ulcer
3235:
3210:
3180:Gas gangrene
3169:
3153:
3127:
3100:
3070:
2973:Enzyme assay
2819:
2814:
2803:Karyorrhexis
2779:Myocytolysis
2769:Fat necrosis
2758:
2674:Inflammation
2662:Hemodynamics
2655:Pathogenesis
2578:
2431:
2405:
2394:
2370:
2359:
2348:
2329:
2302:
2287:
2241:
2230:. Retrieved
2220:
2211:
2206:
2171:
2167:
2157:
2142:
2130:
2118:. Retrieved
2114:
2104:
2092:. Retrieved
2087:
2078:
2051:
2045:
2035:
2018:
2005:
1996:
1971:
1967:
1961:
1936:
1932:
1926:
1914:. Retrieved
1905:
1892:
1888:
1861:
1857:
1847:
1822:
1818:
1812:
1779:
1775:
1769:
1749:
1742:
1730:. Retrieved
1725:
1715:
1704:. Retrieved
1702:. 2019-02-21
1699:
1690:
1678:. Retrieved
1674:
1665:
1648:
1644:
1640:
1630:
1597:
1591:
1587:
1581:
1546:
1542:
1486:
1482:
1472:
1453:
1447:
1412:
1408:
1397:
1370:
1366:
1355:
1310:
1306:
1269:. Retrieved
1254:
1247:
1228:
1222:
1205:
1201:
1195:
1160:
1156:
1108:
1104:
1094:
1082:. Retrieved
1077:
1068:
1056:. Retrieved
1052:
1022:. Retrieved
1017:
989:. Retrieved
984:
952:. Retrieved
948:patient.info
947:
921:. Retrieved
916:
880:putrefaction
854:
834:
824:
818:French King
817:
802:
793:
769:
743:
737:
721:
718:
711:
707:
695:
661:
653:
645:
587:
564:
560:streptococci
553:
547:
538:
528:
526:
523:Gas gangrene
517:Gas gangrene
504:
497:
491:
481:
470:Wet gangrene
461:
438:
429:putrefaction
412:
399:
396:Dry gangrene
383:
375:
331:
315:gas gangrene
311:wet gangrene
307:dry gangrene
271:dengue fever
251:major trauma
236:
222:caused by a
220:tissue death
215:
214:
152:major trauma
135:Risk factors
4001:Pyomyositis
3709:Shigellosis
3679:Pseudomonas
3603:Melioidosis
3569:Oroya fever
3559:Brucellosis
3391:Nocardiosis
3201:Listeriosis
3171:Clostridium
2827:Hemosiderin
2708:Hyperplasia
2703:Hypertrophy
2679:Cell damage
2547:Hemorrhagic
2396:MedlinePlus
1700:www.cdc.gov
1641:Clostridium
1409:Circulation
1313:: 255–264.
1084:12 December
1058:12 December
1024:12 December
991:12 December
954:12 December
923:12 December
794:The French
685:antibiotics
577:Other types
555:Bacteroides
537:-producing
535:alpha toxin
530:Clostridium
354:angioplasty
338:debridement
334:antibiotics
37:Other names
4046:Categories
3889:Paronychia
3884:Cellulitis
3757:cellulitis
3668:cellulitis
3608:Cutaneous
3212:Mycoplasma
3162:Erythrasma
3135:Erysipelas
3126:Cutaneous
2993:Blood bank
2836:Lipofuscin
2832:Lipochrome
2808:Karyolysis
2737:Cell death
2718:Metaplasia
2531:Infarction
2485:infarction
2433:Patient UK
2361:DiseasesDB
2232:2014-04-15
1974:: S6–S13.
1706:2019-08-05
1014:"Gangrene"
944:"Gangrene"
886:References
837:Union Army
764:Union Army
658:Medication
613:thrombosis
488:saprogenic
342:amputation
279:chickenpox
255:alcoholism
156:alcoholism
102:amputation
3879:Carbuncle
3732:infection
3730:Aeromonas
3724:Chancroid
3648:Tularemia
3612:infection
3594:Gonorrhea
3504:infection
3404:infection
3325:infection
3317:infection
3309:infection
3130:infection
3062:Bacillota
2848:Steatosis
2791:Apoptosis
2728:Glandular
2713:Dysplasia
2645:Neoplasia
2640:Infection
2621:Pathology
2553:Location
2500:Location
2481:Ischaemia
2407:eMedicine
2377:372070002
2372:SNOMED CT
1899:eMedicine
1637:Chuang YC
1329:1178-7007
875:gangraina
866:gangraena
857:etymology
851:Etymology
841:mortality
820:Louis XIV
813:amputated
650:Lifestyle
642:Treatment
484:prognosis
445:infection
267:influenza
263:frostbite
206:Frequency
197:Prognosis
188:Treatment
168:frostbite
63:Specialty
4067:Necrosis
4052:Gangrene
3964:Gangrene
3915:Pyoderma
3848:pathogen
3778:Syphilis
3773:Syphilid
3622:Glanders
3427:Gram -ve
3111:Impetigo
3086:Impetigo
3053:Gram +ve
3003:Serology
2798:Pyknosis
2744:Necrosis
2723:Squamous
2667:Ischemia
2579:Gangrene
2493:Ischemia
2438:Gangrene
2265:Gangrene
2198:26732207
2190:21944621
2120:12 March
2094:March 7,
2070:24841930
2054:: 32–7.
1988:25478859
1953:23374620
1916:July 24,
1880:10575138
1839:20659659
1796:18349455
1732:5 August
1728:. cfpmfc
1622:12940936
1614:15632295
1573:24715679
1513:22694053
1439:27840333
1389:24486336
1347:29910628
1214:22216805
1187:26631369
1135:19008688
789:efficacy
698:debrided
669:ischemia
550:exotoxin
457:emergent
443:without
441:ischemia
406:ischemic
390:diabetes
259:HIV/AIDS
239:diabetes
216:Gangrene
201:Variable
164:HIV/AIDS
140:Diabetes
124:internal
83:Symptoms
76:podiatry
32:Gangrene
3944:Ecthyma
3855:Abscess
3783:Chancre
3699:Q fever
3286:Leprosy
3238:related
2876:Autopsy
2841:Melanin
2821:pigment
2698:Atrophy
2635:Disease
2355:D005734
2168:Am Surg
2006:fda.gov
1804:2930176
1680:22 July
1657:8541740
1564:7154343
1521:5693425
1504:7950796
1430:5477786
1338:5987754
1271:8 April
1178:8652263
1126:2743684
845:bromide
804:Te Deum
776:maggots
755:History
692:Surgery
629:Severe
618:Severe
567:toxemia
275:malaria
247:smoking
209:Unknown
148:smoking
72:surgery
3939:Pimple
3714:Plague
3379:Others
3194:Others
2567:Spleen
2542:Anemic
2538:Types
2401:007218
2215:. 1863
2196:
2188:
2068:
2008:. US:
1986:
1951:
1878:
1837:
1802:
1794:
1757:
1655:
1620:
1612:
1571:
1561:
1519:
1511:
1501:
1460:
1437:
1427:
1387:
1345:
1335:
1327:
1262:
1235:
1212:
1185:
1175:
1133:
1123:
780:ulcers
724:tibial
679:, and
409:tissue
380:Causes
321:, and
283:plague
232:sepsis
160:plague
98:Sepsis
3798:Bejel
3793:Pinta
3766:Other
3636:Gamma
3444:Alpha
2650:Cause
2562:Brain
2557:Heart
2509:Heart
2504:Brain
2366:19273
2344:785.4
2340:040.0
2325:I73.9
2321:E10.2
2317:I70.2
2194:S2CID
2027:(PDF)
1800:S2CID
1618:S2CID
1517:S2CID
871:Greek
863:word
861:Latin
809:baton
772:flies
734:Other
571:shock
228:fever
108:Types
3788:Yaws
3583:Beta
2572:Limb
2483:and
2350:MeSH
2335:9-CM
2298:MC85
2186:PMID
2122:2017
2096:2017
2066:PMID
1984:PMID
1949:PMID
1918:2013
1876:PMID
1835:PMID
1792:PMID
1755:ISBN
1734:2024
1682:2021
1653:PMID
1610:PMID
1569:PMID
1509:PMID
1458:ISBN
1435:PMID
1385:PMID
1343:PMID
1325:ISSN
1273:2020
1260:ISBN
1233:ISBN
1210:PMID
1183:PMID
1161:2015
1131:PMID
1086:2017
1060:2017
1026:2017
993:2017
956:2017
925:2017
855:The
774:and
726:and
611:and
596:Noma
569:and
301:and
2331:ICD
2323:,
2319:,
2315:,
2313:R02
2304:ICD
2289:ICD
2176:doi
2056:doi
1976:doi
1941:doi
1897:at
1866:doi
1827:doi
1784:doi
1602:doi
1598:136
1559:PMC
1551:doi
1499:PMC
1491:doi
1425:PMC
1417:doi
1413:135
1375:doi
1333:PMC
1315:doi
1173:PMC
1165:doi
1121:PMC
1113:doi
1078:NHS
1053:NHS
1018:NHS
985:NHS
917:NHS
496:or
413:dry
352:or
230:or
120:gas
116:wet
112:Dry
4048::
3891:/
3691:/
3687:/
3683:/
3676:/
3137:/
2436::
2410::
2399::
2375::
2364::
2353::
2342:,
2338::
2311::
2308:10
2296::
2293:11
2192:.
2184:.
2172:77
2170:.
2166:.
2113:.
2086:.
2064:.
2052:25
2050:.
2044:.
2004:.
1982:.
1972:19
1970:.
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