380:
771:
843:, from 1795 on Director of the Medical Bureau of the Batavian Republic, and inspector-general of the French Imperial Military Health-Service in 1811, became a leading expert in the fight against hospital-gangrene and its prevention. He wrote a treatise on gangrene in 1814 in which he meticulously analyzed and explained the causes of this dreadful disease, which he was convinced was contagious. He completed his entry with a thorough evaluation of all possible and well experienced sanitary regulations. His work was very well received and was instrumental in convincing most later authors that gangrene was a contagious disease.
486:
513:, for example), which cause tissue to swell and emit a foul odor. Wet gangrene usually develops rapidly due to blockage of venous (mainly) or arterial blood flow. The affected part is saturated with stagnant blood, which promotes the rapid growth of bacteria. The toxic products formed by bacteria are absorbed, causing systemic manifestation of sepsis and finally death. The affected part is edematous, soft, putrid, rotten, and dark.
58:
2271:
573:. These environmental bacteria may enter the muscle through a wound and subsequently proliferate in necrotic tissue and secrete powerful toxins that destroy nearby tissue, generating gas at the same time. A gas composition of 5.9% hydrogen, 3.4% carbon dioxide, 74.5% nitrogen, and 16.1% oxygen was reported in one clinical case.
677:
and antibiotics. Since gangrene is associated with periodic pain caused by too little blood flow, pain management is important so patients can continue doing exercises that promote circulation. Pain management medications can include opioids and opioid-like analgesics. Since gangrene is a result of
596:
is a rare infection that spreads deep into the body along tissue planes. It is categorized into four subtypes, with the first two being the most common. Type 1 requires an infection with an anaerobe and a species in the
Enterobacteriaceae family, while type 2 is characterized by infection with
1413:
Gerhard-Herman, MD; Gornik, HL; Barrett, C; Barshes, NR; Corriere, MA; Drachman, DE; Fleisher, LA; Fowkes, FG; Hamburg, NM; Kinlay, S; Lookstein, R; Misra, S; Mureebe, L; Olin, JW; Patel, RA; Regensteiner, JG; Schanzer, A; Shishehbor, MH; Stewart, KJ; Treat-Jacobson, D; Walsh, ME (2017).
719:
Dead tissue alone does not require debridement, and in some cases, such as dry gangrene, the affected part falls off (autoamputates), making surgical removal unnecessary. Waiting for autoamputation, however, may cause health complications as well as decreased quality of life.
793:
to prevent or arrest necrotic spread, as some species of maggots consume only dead flesh, leaving nearby living tissue unaffected. This practice largely died out after the introduction of antibiotics to the range of treatments for wounds. In recent times, however,
476:
is a risk factor for peripheral vascular disease, thus for dry gangrene, but also a risk factor for wet gangrene, particularly in patients with poorly controlled blood sugar levels, as elevated serum glucose creates a favorable environment for bacterial infection.
698:
are often a critical component of its treatment. The life-threatening nature of gangrene requires treatment with intravenous antibiotics in an inpatient setting. Antibiotics alone are not effective because they may not penetrate infected tissues sufficiently.
552:, or various nonclostridial species. Infection spreads rapidly as the gases produced by the bacteria expand and infiltrate healthy tissue in the vicinity. Because of its ability to quickly spread to surrounding tissues, gas gangrene should be treated as a
442:
and bacteria fail to survive. The affected part is dry, shrunken, and dark reddish-black. The line of separation usually brings about complete separation, with eventual falling off of the gangrenous tissue if it is not removed surgically, a process called
2160:"Verhandeling ter beantwoording der vrage: Kan de gesteldheid en zamenstelling van den dampkring, welke onmiddelijk tot de Hospitaal-versterving (Gangraena NosocomialisZ) aanleiding geeft, door Natuur- of Scheikundige middelen worden ontdekt?"
237:. Symptoms may include a change in skin color to red or black, numbness, swelling, pain, skin breakdown, and coolness. The feet and hands are most commonly affected. If the gangrene is caused by an infectious agent, it may present with a
1371:
Aiello A, Anichini R, Brocco E, Caravaggi C, Chiavetta A, Cioni R, Da Ros R, De Feo ME, Ferraresi R, Florio F, Gargiulo M, Galzerano G, Gandini R, Giurato L, Graziani L, Mancini L, Manzi M, Modugno P, Setacci C, Uccioli L (2014).
711:
to hinder the spread of the associated infection. The extent of surgical debridement needed depends on the extent of the gangrene and may be limited to the removal of a finger, toe, or ear, but in severe cases may involve a
1416:"2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines"
2341:
2314:
2299:
466:(via vascular bypass or angioplasty). However, once gangrene has developed, the affected tissues are not salvageable. Because dry gangrene is not accompanied by infection, it is not as
707:
Surgical removal of all dead tissue, however, is the mainstay of treatment for gangrene. Often, gangrene is associated with underlying infection, thus the gangrenous tissue must be
858:
solutions on infected wounds to reduce the incidence and virulence of "poisoned miasma". Copies of his book were issued to Union surgeons to encourage the use of his methods.
1374:"Treatment of peripheral arterial disease in diabetes: a consensus of the Italian Societies of Diabetes (SID, AMD), Radiology (SIRM) and Vascular Endovascular Surgery (SICVE)"
752:
treatment is used to treat gas gangrene. It increases pressure and oxygen content to allow blood to carry more oxygen to inhibit anaerobic organism growth and reproduction.
1942:
Liu R, Li L, Yang M, Boden G, Yang G (2013). "Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers".
470:
as gas gangrene or wet gangrene, both of which have a risk of sepsis. Over time, dry gangrene may develop into wet gangrene if an infection develops in the dead tissues.
383:
An illustration showing four different stages of gangrene, including one (Fig. 4 top right) caused by an obstacle to the return of the venous blood due to heart disease.
497:(compared to dry gangrene) due to sepsis resulting from the free communication between infected fluid and circulatory fluid. In wet gangrene, the tissue is infected by
730:
Ischemic disease of the legs is the most common reason for amputations. In about a quarter of these cases, the other side requires amputation in the next three years.
854:
was 45%. Goldsmith's method, which he applied to over 330 cases, yielded a mortality under 3%." Goldsmith advocated the use of debridement and topical and injected
3046:
850:
during the
American Civil War, meticulously studied hospital gangrene and developed a revolutionary treatment regimen. The cumulative Civil War hospital gangrene
516:
Because of the high mortality associated with infected gangrene (about 80% without treatment and 20% with treatment), an emergency salvage amputation, such as a
438:. As a result, people with atherosclerosis, high cholesterol, diabetes and smokers commonly have dry gangrene. The limited oxygen in the ischemic limb limits
3316:
387:
Symptoms may include a change in skin color to red or black, numbness, pain, skin breakdown, and coolness. The feet and hands are most commonly involved.
2482:
3039:
2057:
4031:
3618:
3126:
426:
is used only when referring to a limb or to the gut (in other locations, this same type of necrosis is called an infarction, such as
723:
After the gangrene is treated with debridement and antibiotics, the underlying cause can be treated. In the case of gangrene due to
520:, is often needed to limit systemic effects of the infection. Such an amputation can be converted to a formal amputation, such as a
422:, where the blood supply is inadequate to keep tissue viable. It is not a disease itself, but a symptom of other diseases. The term
3136:
3032:
3411:
2475:
78:
770:
4072:
3350:
1769:
379:
3529:
3091:
1211:
Korzon-Burakowska, A; Dziemidok, P (December 2011). "Diabetic foot-the need for comprehensive multidisciplinary approach".
3979:
3324:
2622:
545:
4067:
3511:
2933:
1472:
1247:
329:
134:
2012:
3937:
3675:
3534:
3437:
2468:
1274:
3345:
3332:
2901:
619:
3843:
3419:
2175:"Gangrene therapy and antisepsis before lister: the civil war contributions of Middleton Goldsmith of Louisville"
309:
3584:
3406:
3360:
3271:
3261:
4082:
3688:
3608:
3554:
2094:
3996:
3524:
3365:
3149:
2020:
1490:"Necrotising fasciitis in the central part of the body: diagnosis, management and review of the literature"
17:
1706:
4016:
3637:
3549:
2145:
Teun van
Heiningen, "Sebald Justinus Brugmans' strijd tegen de hospitaalversterving", Leiden University,
396:
253:
154:
4036:
3838:
2237:
3564:
3340:
2275:
2121:
727:, revascularization can be performed to treat the underlying peripheral underlateral artery disease.
431:
368:
66:
31:
4087:
3833:
3539:
3506:
3216:
3131:
3082:
2360:
836:
347:
to treat any infection, and efforts to address the underlying cause. Surgical efforts may include
3964:
3764:
3501:
3476:
3396:
3008:
2615:
2519:
1785:
Levenson, RB; Singh, AK; Novelline, RA (March–April 2008). "Fournier gangrene: role of imaging".
1603:
734:
503:
103:
3544:
3496:
3486:
3481:
3370:
3055:
724:
599:
2411:
2053:"A systematic review of maggot debridement therapy for chronically infected wounds and ulcers"
1921:
1759:
3991:
3969:
3882:
3195:
2796:
2764:
2567:
2308:
1828:
Warkentin, TE (August 2010). "Agents for the treatment of heparin-induced thrombocytopenia".
603:, a Gram-positive cocci bacteria, and thus is also known as hemolytic streptococcal gangrene.
593:
521:
517:
427:
333:
313:
305:
182:
138:
2159:
563:-producing clostridial species, which are mostly found in soil, and other anaerobes such as
538:
Gas gangrene is a bacterial infection that produces gas within tissues. It can be caused by
4026:
3695:
3684:
3311:
3301:
3101:
2966:
2961:
2918:
2868:
2759:
2738:
2034:
412:
2437:
2434:
1904:
8:
3908:
3903:
3813:
3739:
3729:
3703:
3699:
3574:
3380:
3291:
3063:
2923:
2891:
2733:
2701:
2572:
2557:
2529:
2431:
2428:
2425:
2422:
2345:
830:
809:
790:
759:
749:
630:
509:
498:
435:
2221:
1732:
3959:
3870:
3281:
3266:
3256:
2951:
2943:
2928:
2896:
2876:
2784:
2608:
2577:
2204:
1810:
1628:
1574:
1549:
1527:
1514:
1489:
1440:
1415:
1348:
1313:
1188:
1163:
1136:
1111:
851:
833:
died of gangrene in his leg on 1 September 1715, four days prior to his 77th birthday.
819:
674:
609:
is a gangrene of the face most often found in Africa, Southeast Asia and South
America.
301:
93:
2354:
2350:
1881:
1864:
4077:
4062:
3984:
3664:
3375:
2988:
2371:
2196:
2076:
1994:
1977:
Shi, Eric; Shofler, David (2014). "Maggot debridement therapy: A systematic review".
1959:
1886:
1845:
1802:
1765:
1663:
1620:
1579:
1519:
1505:
1468:
1445:
1395:
1353:
1335:
1270:
1243:
1220:
1193:
1141:
840:
683:
673:
Medications may include pain management, medications that promote circulation in the
612:
553:
473:
463:
189:
73:
2208:
1632:
1084:
1059:
4021:
3942:
3756:
3724:
2908:
2774:
2660:
2524:
2186:
2066:
1990:
1986:
1951:
1876:
1837:
1814:
1794:
1647:
1612:
1569:
1565:
1561:
1531:
1509:
1501:
1435:
1427:
1385:
1343:
1325:
1183:
1179:
1175:
1131:
1123:
923:
641:
419:
293:
170:
2146:
1681:
3915:
3803:
3627:
3559:
3466:
3286:
3165:
2976:
2956:
2582:
2365:
1955:
1431:
1390:
1373:
1264:
1127:
991:
738:
645:
634:
337:
2071:
2052:
812:
contracted gangrene in
January 1687 when, while conducting a performance of his
493:
Wet, or infected, gangrene is characterized by thriving bacteria and has a poor
336:. The diagnosis of gangrene is based on symptoms and supported by tests such as
4041:
3920:
3823:
3653:
3519:
3461:
3446:
3306:
3237:
2998:
2993:
2913:
2552:
2514:
2376:
2191:
2174:
881:
795:
615:
is a type of necrotizing fasciitis that usually affects the genitals and groin.
606:
459:
444:
360:
356:
2335:
2331:
2327:
1841:
98:
Change in skin color to red or black, numbness, pain, skin breakdown, coolness
4056:
4001:
3818:
3714:
3670:
3355:
3154:
3112:
2881:
2694:
1339:
806:
755:
691:
687:
570:
297:
194:
Based on symptom, With medical imaging used to identify the underlying cause.
2323:
682:, circulatory system management is important. These medications can include
576:
Gas gangrene can cause necrosis, gas production, and sepsis. Progression to
467:
4006:
3932:
3828:
3600:
3491:
3471:
3276:
3190:
2983:
2813:
2789:
2779:
2684:
2672:
2665:
2460:
2200:
2080:
1998:
1963:
1890:
1849:
1806:
1624:
1583:
1523:
1449:
1399:
1357:
1224:
1197:
1145:
890:
822:). The disease spread to his leg, but the composer refused to have his toe
581:
533:
485:
439:
325:
321:
317:
281:
261:
162:
130:
126:
122:
1667:
1162:
Yang, Z; Hu, J; Qu, Y; Sun, F; Leng, X; Li, H; Zhan, S (3 December 2015).
1024:
733:
Angioplasty should be considered if severe blockage in lower leg vessels (
4011:
3719:
3613:
3579:
3569:
3401:
3211:
3181:
3024:
2971:
2837:
2718:
2713:
2689:
2406:
1798:
1330:
708:
695:
565:
540:
364:
348:
344:
145:
1616:
3899:
3894:
3222:
3172:
3145:
3003:
2846:
2842:
2818:
2747:
2728:
2541:
2495:
2448:
2443:
954:
847:
823:
774:
713:
623:
577:
352:
289:
265:
166:
112:
2291:
3889:
3734:
3658:
3604:
3072:
2858:
2801:
2723:
2650:
2631:
2491:
2417:
2382:
1909:
1314:"Autoamputation of diabetic toe with dry gangrene: a myth or a fact?"
884:
867:
818:, he stabbed his own toe with his pointed staff (which was used as a
494:
455:
277:
273:
207:
178:
2256:
Liddell & Scott's
Lexicon, Oxford University Press, 1963 edition
777:
Private Milton E. Wallen lies in bed with a gangrenous amputated arm
395:
Gangrene is caused by a critically insufficient blood supply (e.g.,
3925:
3788:
3783:
3632:
3121:
3096:
3013:
2808:
2754:
2677:
2655:
2503:
799:
798:
has regained some credibility and is sometimes employed with great
679:
560:
451:
416:
400:
269:
249:
234:
230:
174:
150:
86:
2387:
1731:
Puvanendran, Rukshini; Chan Meng Huey, Jason; Pasupathy, Shanker.
1412:
3954:
3865:
3793:
3709:
3296:
2886:
2851:
2831:
2708:
2645:
1488:
Vayvada, H; Demirdover, C; Menderes, A; Karaca, C (August 2013).
855:
814:
285:
257:
158:
82:
462:
rather than gangrene are present, the process can be treated by
3949:
2318:
2303:
2270:
2051:
Sun, Xinjuan; Jiang, Kechun; Chen, Jingan; et al. (2014).
1865:"Evidence-based antibiotic therapy of diabetic foot infections"
1487:
846:
John M. Trombold wrote: "Middleton
Goldsmith, a surgeon in the
786:
242:
108:
57:
1730:
3808:
2238:"Hospital Gangrene During The Civil War – Civil War Medicine"
1370:
1318:
Diabetes, Metabolic
Syndrome and Obesity: Targets and Therapy
871:
657:
Treatment varies based on the severity and type of gangrene.
371:
may be useful. How commonly the condition occurs is unknown.
238:
2600:
665:
Exercises such as walking and massage therapy may be tried.
3877:
3798:
1757:
1112:"Management of lower extremity peripheral arterial disease"
826:, which eventually led to his death in March of that year.
1210:
782:
343:
Treatment may involve surgery to remove the dead tissue,
27:
Type of tissue death by infection or lack of blood supply
1758:
Sivapathasundharam, B.; Rajendran, Arya (30 June 2012).
1116:
762:
have successfully altered gangrene and ulcer prognosis.
1922:"Angioplasty and stent placement – peripheral arteries"
1269:(7th ed.). Elsevier Health Sciences. p. 124.
1784:
2223:
A report on hospital gangrene, erysipelas and pyaemia
1597:
Sakurai, J.; Nagahama, M.; Oda, M. (November 2004). "
2281:
359:. Efforts to treat the underlying cause may include
1601:alpha-toxin: characterization and mode of action".
1645:
1596:
694:. As infection is often associated with gangrene,
1213:Annals of Agricultural and Environmental Medicine
4054:
1707:"For Clinicians: Type II Necrotizing Fasciitis"
1110:Gardner, AW; Afaq, A (November–December 2008).
65:Dry gangrene affecting the toes as a result of
2050:
1941:
789:were commonly used to treat chronic wounds or
3040:
2616:
2476:
1650:, Wu MH (December 1995). "Gas composition in
1019:
1017:
1015:
1013:
2490:
2058:International Journal of Infectious Diseases
1830:Hematology/Oncology Clinics of North America
1550:"Type of incision for below knee amputation"
986:
984:
982:
980:
978:
976:
918:
916:
914:
912:
910:
908:
906:
2172:
2162:. J. van der Heij – via Google Books.
1656:Journal of the Formosan Medical Association
1554:The Cochrane Database of Systematic Reviews
1168:The Cochrane Database of Systematic Reviews
1161:
1109:
1054:
1052:
1050:
1048:
1046:
875:
4032:Recurrent toxin-mediated perineal erythema
3318:Mycobacterium avium–intracellulare complex
3054:
3047:
3033:
2623:
2609:
2483:
2469:
2158:Brugmans, Sebald Justinus (May 24, 1814).
2013:"Product Classification: Maggots, Medical"
1976:
1543:
1541:
1266:Underwood's Pathology: A Clinical Approach
1157:
1155:
1010:
56:
3127:Cutaneous group B streptococcal infection
2190:
2119:
2070:
1880:
1862:
1827:
1764:. Elsevier Health Sciences. p. 333.
1573:
1513:
1439:
1389:
1347:
1329:
1187:
1164:"Interventions for treating gas gangrene"
1135:
973:
903:
2157:
1547:
1311:
1043:
949:
947:
945:
769:
484:
378:
1590:
1538:
1240:Gangrene Management: Today and Tomorrow
1152:
14:
4055:
2101:. Utah Symphony Orchestra. August 2010
1462:
618:Venous limb gangrene may be caused by
458:. If ischemia is detected early, when
450:Dry gangrene is the result of chronic
399:) or infection. It is associated with
3351:Rapid growing mycobacterium infection
3028:
2604:
2464:
1307:
1305:
1303:
1301:
1299:
1297:
1295:
1293:
1262:
1237:
942:
802:in cases of chronic tissue necrosis.
374:
3530:Human granulocytotropic anaplasmosis
3092:Staphylococcal scalded skin syndrome
2120:Laurenson, John (21 November 2015).
1979:British Journal of Community Nursing
1686:The Lecturio Medical Concept Library
559:Gas gangrene is caused by bacterial
3980:Chronic undermining burrowing ulcer
2095:"Music Trivia – The Death of Lully"
1970:
1761:Shafer's Textbook of Oral Pathology
1548:Tisi, PV; Than, MM (8 April 2014).
24:
2934:Fluorescence in situ hybridization
2235:
1905:Amputations of the Lower Extremity
1290:
25:
4099:
3938:Superficial pustular folliculitis
3535:Human monocytotropic ehrlichiosis
2263:
1312:Al Wahbi, Abdullah (2018-06-01).
3346:Primary inoculation tuberculosis
2902:Oral and maxillofacial pathology
2269:
2122:"The strange death of Louis XIV"
1506:10.1111/j.1742-481x.2012.01006.x
620:Heparin-induced thrombocytopenia
430:). Dry gangrene is often due to
3844:Gram-negative toe web infection
3420:Group JK corynebacterium sepsis
2250:
2229:
2215:
2166:
2151:
2139:
2113:
2087:
2044:
2027:
2005:
1935:
1914:
1897:
1856:
1821:
1778:
1751:
1724:
1699:
1674:
1639:
1481:
1456:
1406:
1364:
1256:
1231:
527:
522:below- or above-knee amputation
480:
406:
403:and long-term tobacco smoking.
310:Group B streptococcal infection
3585:Ehrlichiosis ewingii infection
3407:Cutaneous diphtheria infection
3361:Tuberculosis cutis orificialis
3272:Borderline tuberculoid leprosy
3262:Borderline lepromatous leprosy
1991:10.12968/bjcn.2014.19.Sup12.S6
1566:10.1002/14651858.CD003749.pub3
1204:
1180:10.1002/14651858.CD010577.pub2
1103:
1077:
644:may result in gangrene of the
633:may result in gangrene of the
587:
13:
1:
3609:Primary gonococcal dermatitis
3555:Flinders Island spotted fever
2630:
1882:10.1016/s0928-8244(99)00143-1
896:
870:of gangrene derives from the
668:
4073:Symptoms and signs: Vascular
3997:Blistering distal dactylitis
3525:Rocky Mountain spotted fever
3413:Arcanobacterium haemolyticum
3366:Tuberculosis verrucosa cutis
3150:Chronic recurrent erysipelas
2021:Food and Drug Administration
1956:10.1016/j.mayocp.2012.10.021
1869:FEMS Immunol. Med. Microbiol
1737:national library of medicine
1432:10.1161/CIR.0000000000000471
1391:10.1016/j.numecd.2013.12.007
1128:10.1097/HCR.0b013e31818c3b96
885:
861:
660:
652:
7:
4017:Blastomycosis-like pyoderma
3638:Chromobacteriosis infection
3550:Mediterranean spotted fever
2072:10.1016/j.ijid.2014.03.1397
1863:Lipsky BA (December 1999).
1646:Chi CH, Chen KW, Huang JJ,
1494:International Wound Journal
397:peripheral vascular disease
254:peripheral arterial disease
202:Depends on underlying cause
155:peripheral arterial disease
10:
4104:
4037:Tick-borne lymphadenopathy
3839:Gram-negative folliculitis
2192:10.1177/000313481107700924
889:(γάγγραινα), which means "
765:
702:
531:
411:Dry gangrene is a form of
316:. It can be classified as
29:
4068:Health effects of tobacco
3856:
3776:
3755:
3646:
3593:
3454:
3445:
3436:
3389:
3341:Papulonecrotic tuberculid
3326:Mycobacterium haemophilum
3245:
3236:
3204:
3179:
3163:
3110:
3080:
3071:
3062:
2942:
2867:
2638:
2540:
2502:
2397:
2285:
2147:URN:NBN:NL:UI:10-1-112565
2035:"FDA CDRH 510(k) summary"
1842:10.1016/j.hoc.2010.05.009
1378:Nutr Metab Cardiovasc Dis
750:Hyperbaric oxygen therapy
489:Wet gangrene of the foot.
432:peripheral artery disease
390:
369:hyperbaric oxygen therapy
216:
206:
198:
188:
144:
118:
102:
92:
72:
67:peripheral artery disease
64:
55:
47:
42:
32:Gangrene (disambiguation)
3834:Lymphogranuloma venereum
3540:Flea-borne spotted fever
3513:Rickettsia aeschlimannii
3507:American tick bite fever
3217:Erysipeloid of Rosenbach
3132:Streptococcal intertrigo
1654:septicum gas gangrene".
837:Sebald Justinus Brugmans
744:
3965:Trichomycosis axillaris
3502:African tick bite fever
3477:North Asian tick typhus
3397:Cutaneous actinomycosis
3009:Microbiological culture
2639:Principles of pathology
1733:"Necrotizing fasciitis"
1604:Journal of Biochemistry
1599:Clostridium perfringens
504:Clostridium perfringens
3677:Haemophilus influenzae
3621:Pasteurella hemolytica
3545:Japanese spotted fever
3497:Bacillary angiomatosis
3487:Flying squirrel typhus
3482:Queensland tick typhus
3371:Tuberculous cellulitis
3334:Mycobacterium kansasii
3056:Bacterial skin disease
876:
778:
725:critical limb ischemia
600:Streptococcus pyogenes
490:
384:
3992:Elephantiasis nostras
3970:Necrotizing fasciitis
3883:Hospital furunculosis
3565:Brill–Zinsser disease
3196:Dermatitis gangrenosa
2972:Diagnostic immunology
2797:Programmed cell death
2765:Liquefactive necrosis
2099:The Musician's Lounge
1463:Nather, Aziz (2013).
1263:Cross, Simon (2018).
1238:Smith, Tyler (2015).
773:
741:) leads to gangrene.
594:Necrotizing fasciitis
584:is often very rapid.
518:guillotine amputation
488:
428:myocardial infarction
382:
334:necrotizing fasciitis
306:meningococcal disease
248:Risk factors include
139:necrotizing fasciitis
4083:Causes of amputation
4027:Chronic lymphangitis
3696:Hot tub folliculitis
3685:Pseudomonal pyoderma
3312:Miliary tuberculosis
3302:Lichen scrofulosorum
3102:Toxic shock syndrome
2967:Medical microbiology
2962:Transfusion medicine
2919:Immunohistochemistry
2869:Anatomical pathology
2760:Coagulative necrosis
2278:at Wikimedia Commons
2173:Trombold JM (2011).
1799:10.1148/rg.282075048
1467:. World Scientific.
1331:10.2147/DMSO.S164199
1085:"Gangrene Diagnosis"
1060:"Gangrene Treatment"
756:Regenerative medical
434:, but can be due to
413:coagulative necrosis
367:. In certain cases,
235:lack of blood supply
30:For other uses, see
3916:Acute lymphadenitis
3909:Perianal cellulitis
3904:Pyogenic paronychia
3814:Chlamydia infection
3730:Granuloma inguinale
3704:Green nail syndrome
3700:Ecthyma gangrenosum
3575:Cat-scratch disease
3381:Tuberculoid leprosy
3292:Lepromatous leprosy
3139:Streptococcus iniae
2924:Electron microscopy
2892:Molecular pathology
2770:Gangrenous necrosis
2702:Cellular adaptation
2236:Watson, Dr. Scott.
924:"Gangrene Symptoms"
810:Jean-Baptiste Lully
760:stem-cell therapies
631:mesenteric ischemia
510:Bacillus fusiformis
436:acute limb ischemia
51:Gangrenous necrosis
3960:Pitted keratolysis
3871:Periapical abscess
3282:Erythema induratum
3267:Borderline leprosy
3257:Aquarium granuloma
2952:Clinical chemistry
2944:Clinical pathology
2929:Immunofluorescence
2897:Forensic pathology
2877:Surgical pathology
2785:Fibrinoid necrosis
2398:External resources
781:As early as 1028,
779:
675:circulatory system
491:
385:
375:Signs and symptoms
314:Raynaud's syndrome
302:radiation injuries
183:Raynaud's syndrome
79:Infectious disease
4050:
4049:
3985:Fournier gangrene
3852:
3851:
3751:
3750:
3692:hot-foot syndrome
3665:Vibrio vulnificus
3432:
3431:
3428:
3427:
3376:Tuberculous gumma
3232:
3231:
3022:
3021:
2989:Mass spectrometry
2598:
2597:
2458:
2457:
2274:Media related to
1771:978-81-312-3800-4
1617:10.1093/jb/mvh161
1465:The diabetic foot
1242:. Hayle Medical.
1091:. 13 October 2015
1031:. 13 October 2015
998:. 13 October 2015
992:"Gangrene Causes"
930:. 13 October 2015
841:Leyden University
684:antiplatelet drug
613:Fournier gangrene
554:medical emergency
474:Diabetes mellitus
464:revascularization
415:that develops in
330:internal gangrene
224:
223:
190:Diagnostic method
37:Medical condition
16:(Redirected from
4095:
4022:Bullous impetigo
3943:Sycosis vulgaris
3757:Campylobacterota
3706:
3452:
3451:
3443:
3442:
3243:
3242:
3078:
3077:
3069:
3068:
3049:
3042:
3035:
3026:
3025:
2909:Gross processing
2775:Caseous necrosis
2625:
2618:
2611:
2602:
2601:
2485:
2478:
2471:
2462:
2461:
2283:
2282:
2273:
2257:
2254:
2248:
2247:
2245:
2244:
2233:
2227:
2219:
2213:
2212:
2194:
2170:
2164:
2163:
2155:
2149:
2143:
2137:
2136:
2134:
2132:
2117:
2111:
2110:
2108:
2106:
2091:
2085:
2084:
2074:
2048:
2042:
2041:
2039:
2031:
2025:
2024:
2009:
2003:
2002:
1974:
1968:
1967:
1939:
1933:
1932:
1930:
1928:
1918:
1912:
1901:
1895:
1894:
1884:
1860:
1854:
1853:
1825:
1819:
1818:
1782:
1776:
1775:
1755:
1749:
1748:
1746:
1744:
1728:
1722:
1721:
1719:
1718:
1703:
1697:
1696:
1694:
1692:
1678:
1672:
1671:
1643:
1637:
1636:
1594:
1588:
1587:
1577:
1545:
1536:
1535:
1517:
1485:
1479:
1478:
1460:
1454:
1453:
1443:
1410:
1404:
1403:
1393:
1368:
1362:
1361:
1351:
1333:
1309:
1288:
1287:
1285:
1283:
1260:
1254:
1253:
1235:
1229:
1228:
1208:
1202:
1201:
1191:
1174:(12): CD010577.
1159:
1150:
1149:
1139:
1107:
1101:
1100:
1098:
1096:
1081:
1075:
1074:
1072:
1070:
1056:
1041:
1040:
1038:
1036:
1021:
1008:
1007:
1005:
1003:
988:
971:
970:
968:
966:
951:
940:
939:
937:
935:
920:
888:
879:
807:Baroque composer
642:ischemic colitis
544:, most commonly
501:microorganisms (
355:, or the use of
60:
40:
39:
21:
4103:
4102:
4098:
4097:
4096:
4094:
4093:
4092:
4088:Causes of death
4053:
4052:
4051:
4046:
3858:
3848:
3772:
3747:
3683:
3642:
3628:Meningococcemia
3589:
3560:Verruga peruana
3467:Epidemic typhus
3424:
3385:
3287:Histoid leprosy
3248:
3228:
3200:
3175:
3166:Corynebacterium
3159:
3106:
3058:
3053:
3023:
3018:
2977:Immunopathology
2957:Hematopathology
2938:
2863:
2634:
2629:
2599:
2594:
2536:
2530:Small intestine
2525:Large intestine
2498:
2489:
2459:
2454:
2453:
2438:article/2051157
2435:article/2028899
2393:
2392:
2294:
2266:
2261:
2260:
2255:
2251:
2242:
2240:
2234:
2230:
2220:
2216:
2171:
2167:
2156:
2152:
2144:
2140:
2130:
2128:
2118:
2114:
2104:
2102:
2093:
2092:
2088:
2049:
2045:
2037:
2033:
2032:
2028:
2011:
2010:
2006:
1975:
1971:
1944:Mayo Clin. Proc
1940:
1936:
1926:
1924:
1920:
1919:
1915:
1902:
1898:
1875:(3–4): 267–76.
1861:
1857:
1826:
1822:
1783:
1779:
1772:
1756:
1752:
1742:
1740:
1729:
1725:
1716:
1714:
1705:
1704:
1700:
1690:
1688:
1680:
1679:
1675:
1644:
1640:
1595:
1591:
1560:(4): CD003749.
1546:
1539:
1486:
1482:
1475:
1461:
1457:
1426:(12): e726–79.
1411:
1407:
1369:
1365:
1310:
1291:
1281:
1279:
1277:
1261:
1257:
1250:
1236:
1232:
1209:
1205:
1160:
1153:
1108:
1104:
1094:
1092:
1083:
1082:
1078:
1068:
1066:
1058:
1057:
1044:
1034:
1032:
1023:
1022:
1011:
1001:
999:
990:
989:
974:
964:
962:
961:. 12 March 2014
953:
952:
943:
933:
931:
922:
921:
904:
899:
864:
839:, Professor at
768:
758:treatments and
747:
739:peroneal artery
714:limb amputation
705:
671:
663:
655:
646:large intestine
635:small intestine
590:
536:
530:
483:
460:ischemic wounds
409:
393:
377:
338:medical imaging
38:
35:
28:
23:
22:
15:
12:
11:
5:
4101:
4091:
4090:
4085:
4080:
4075:
4070:
4065:
4048:
4047:
4045:
4044:
4042:Tropical ulcer
4039:
4034:
4029:
4024:
4019:
4014:
4009:
4004:
3999:
3994:
3989:
3988:
3987:
3982:
3972:
3967:
3962:
3957:
3952:
3947:
3946:
3945:
3940:
3929:
3928:
3923:
3921:Pilonidal cyst
3918:
3913:
3912:
3911:
3906:
3892:
3887:
3886:
3885:
3875:
3874:
3873:
3862:
3860:
3854:
3853:
3850:
3849:
3847:
3846:
3841:
3836:
3831:
3826:
3824:Rat-bite fever
3821:
3816:
3811:
3806:
3801:
3796:
3791:
3786:
3780:
3778:
3774:
3773:
3771:
3770:
3761:
3759:
3753:
3752:
3749:
3748:
3746:
3745:
3737:
3732:
3727:
3722:
3717:
3712:
3707:
3681:
3673:
3668:
3661:
3656:
3654:Pasteurellosis
3650:
3648:
3644:
3643:
3641:
3640:
3635:
3630:
3625:
3616:
3611:
3597:
3595:
3591:
3590:
3588:
3587:
3582:
3577:
3572:
3567:
3562:
3557:
3552:
3547:
3542:
3537:
3532:
3527:
3522:
3520:Rickettsialpox
3517:
3509:
3504:
3499:
3494:
3489:
3484:
3479:
3474:
3469:
3464:
3462:Endemic typhus
3458:
3456:
3449:
3447:Pseudomonadota
3440:
3434:
3433:
3430:
3429:
3426:
3425:
3423:
3422:
3417:
3409:
3404:
3399:
3393:
3391:
3387:
3386:
3384:
3383:
3378:
3373:
3368:
3363:
3358:
3353:
3348:
3343:
3338:
3330:
3322:
3314:
3309:
3307:Lupus vulgaris
3304:
3299:
3294:
3289:
3284:
3279:
3274:
3269:
3264:
3259:
3253:
3251:
3247:Mycobacterium-
3240:
3238:Actinomycetota
3234:
3233:
3230:
3229:
3227:
3226:
3219:
3214:
3208:
3206:
3202:
3201:
3199:
3198:
3193:
3187:
3185:
3177:
3176:
3171:
3169:
3161:
3160:
3158:
3157:
3152:
3143:
3134:
3129:
3124:
3118:
3116:
3108:
3107:
3105:
3104:
3099:
3094:
3088:
3086:
3083:Staphylococcus
3075:
3066:
3060:
3059:
3052:
3051:
3044:
3037:
3029:
3020:
3019:
3017:
3016:
3011:
3006:
3001:
2999:Flow cytometry
2996:
2994:Chromatography
2991:
2986:
2980:
2979:
2974:
2969:
2964:
2959:
2954:
2948:
2946:
2940:
2939:
2937:
2936:
2931:
2926:
2921:
2916:
2914:Histopathology
2911:
2905:
2904:
2899:
2894:
2889:
2884:
2879:
2873:
2871:
2865:
2864:
2862:
2861:
2856:
2855:
2854:
2849:
2840:
2828:
2822:
2821:
2816:
2811:
2806:
2805:
2804:
2794:
2793:
2792:
2787:
2782:
2777:
2772:
2767:
2762:
2752:
2750:
2744:
2743:
2742:
2741:
2736:
2726:
2721:
2716:
2711:
2706:
2704:
2698:
2697:
2692:
2687:
2682:
2681:
2680:
2670:
2669:
2668:
2663:
2658:
2653:
2642:
2640:
2636:
2635:
2628:
2627:
2620:
2613:
2605:
2596:
2595:
2593:
2592:
2587:
2586:
2585:
2580:
2575:
2570:
2562:
2561:
2560:
2555:
2546:
2544:
2538:
2537:
2535:
2534:
2533:
2532:
2527:
2522:
2517:
2508:
2506:
2500:
2499:
2488:
2487:
2480:
2473:
2465:
2456:
2455:
2452:
2451:
2440:
2432:article/438994
2429:article/214992
2426:article/782709
2423:article/217943
2414:
2402:
2401:
2399:
2395:
2394:
2391:
2390:
2379:
2368:
2357:
2338:
2311:
2295:
2290:
2289:
2287:
2286:Classification
2280:
2279:
2265:
2264:External links
2262:
2259:
2258:
2249:
2228:
2214:
2185:(9): 1138–43.
2165:
2150:
2138:
2112:
2086:
2043:
2026:
2004:
1969:
1934:
1913:
1896:
1855:
1820:
1777:
1770:
1750:
1723:
1698:
1682:"Gas Gangrene"
1673:
1662:(12): 757–59.
1638:
1589:
1537:
1480:
1474:978-9814417006
1473:
1455:
1405:
1363:
1289:
1275:
1255:
1249:978-1632412232
1248:
1230:
1203:
1151:
1102:
1076:
1042:
1009:
972:
941:
901:
900:
898:
895:
863:
860:
796:maggot therapy
767:
764:
746:
743:
704:
701:
670:
667:
662:
659:
654:
651:
650:
649:
638:
627:
616:
610:
604:
589:
586:
569:and anaerobic
550:C. perfringens
532:Main article:
529:
526:
482:
479:
445:autoamputation
408:
405:
392:
389:
376:
373:
361:bypass surgery
357:maggot therapy
222:
221:
218:
214:
213:
210:
204:
203:
200:
196:
195:
192:
186:
185:
148:
142:
141:
120:
116:
115:
106:
100:
99:
96:
90:
89:
76:
70:
69:
62:
61:
53:
52:
49:
45:
44:
36:
26:
9:
6:
4:
3:
2:
4100:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4069:
4066:
4064:
4061:
4060:
4058:
4043:
4040:
4038:
4035:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4013:
4010:
4008:
4005:
4003:
4002:Botryomycosis
4000:
3998:
3995:
3993:
3990:
3986:
3983:
3981:
3978:
3977:
3976:
3973:
3971:
3968:
3966:
3963:
3961:
3958:
3956:
3953:
3951:
3948:
3944:
3941:
3939:
3936:
3935:
3934:
3931:
3930:
3927:
3924:
3922:
3919:
3917:
3914:
3910:
3907:
3905:
3901:
3898:
3897:
3896:
3893:
3891:
3888:
3884:
3881:
3880:
3879:
3878:Boil/furuncle
3876:
3872:
3869:
3868:
3867:
3864:
3863:
3861:
3855:
3845:
3842:
3840:
3837:
3835:
3832:
3830:
3827:
3825:
3822:
3820:
3819:Leptospirosis
3817:
3815:
3812:
3810:
3807:
3805:
3802:
3800:
3797:
3795:
3792:
3790:
3787:
3785:
3782:
3781:
3779:
3775:
3769:
3767:
3763:
3762:
3760:
3758:
3754:
3744:
3742:
3738:
3736:
3733:
3731:
3728:
3726:
3723:
3721:
3718:
3716:
3715:Salmonellosis
3713:
3711:
3708:
3705:
3701:
3697:
3693:
3691:
3686:
3682:
3680:
3678:
3674:
3672:
3671:Rhinoscleroma
3669:
3667:
3666:
3662:
3660:
3657:
3655:
3652:
3651:
3649:
3645:
3639:
3636:
3634:
3631:
3629:
3626:
3624:
3622:
3617:
3615:
3612:
3610:
3606:
3602:
3599:
3598:
3596:
3592:
3586:
3583:
3581:
3578:
3576:
3573:
3571:
3568:
3566:
3563:
3561:
3558:
3556:
3553:
3551:
3548:
3546:
3543:
3541:
3538:
3536:
3533:
3531:
3528:
3526:
3523:
3521:
3518:
3516:
3514:
3510:
3508:
3505:
3503:
3500:
3498:
3495:
3493:
3490:
3488:
3485:
3483:
3480:
3478:
3475:
3473:
3470:
3468:
3465:
3463:
3460:
3459:
3457:
3453:
3450:
3448:
3444:
3441:
3439:
3435:
3421:
3418:
3416:
3414:
3410:
3408:
3405:
3403:
3400:
3398:
3395:
3394:
3392:
3388:
3382:
3379:
3377:
3374:
3372:
3369:
3367:
3364:
3362:
3359:
3357:
3356:Scrofuloderma
3354:
3352:
3349:
3347:
3344:
3342:
3339:
3337:
3335:
3331:
3329:
3327:
3323:
3321:
3319:
3315:
3313:
3310:
3308:
3305:
3303:
3300:
3298:
3295:
3293:
3290:
3288:
3285:
3283:
3280:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3254:
3252:
3250:
3244:
3241:
3239:
3235:
3225:
3224:
3220:
3218:
3215:
3213:
3210:
3209:
3207:
3203:
3197:
3194:
3192:
3189:
3188:
3186:
3184:
3183:
3178:
3174:
3170:
3168:
3167:
3162:
3156:
3155:Scarlet fever
3153:
3151:
3147:
3144:
3142:
3140:
3135:
3133:
3130:
3128:
3125:
3123:
3120:
3119:
3117:
3115:
3114:
3113:Streptococcus
3109:
3103:
3100:
3098:
3095:
3093:
3090:
3089:
3087:
3085:
3084:
3079:
3076:
3074:
3070:
3067:
3065:
3061:
3057:
3050:
3045:
3043:
3038:
3036:
3031:
3030:
3027:
3015:
3012:
3010:
3007:
3005:
3002:
3000:
2997:
2995:
2992:
2990:
2987:
2985:
2982:
2981:
2978:
2975:
2973:
2970:
2968:
2965:
2963:
2960:
2958:
2955:
2953:
2950:
2949:
2947:
2945:
2941:
2935:
2932:
2930:
2927:
2925:
2922:
2920:
2917:
2915:
2912:
2910:
2907:
2906:
2903:
2900:
2898:
2895:
2893:
2890:
2888:
2885:
2883:
2882:Cytopathology
2880:
2878:
2875:
2874:
2872:
2870:
2866:
2860:
2857:
2853:
2850:
2848:
2844:
2841:
2839:
2836:
2835:
2834:
2833:
2829:
2827:
2826:Accumulations
2824:
2823:
2820:
2817:
2815:
2812:
2810:
2807:
2803:
2800:
2799:
2798:
2795:
2791:
2788:
2786:
2783:
2781:
2778:
2776:
2773:
2771:
2768:
2766:
2763:
2761:
2758:
2757:
2756:
2753:
2751:
2749:
2746:
2745:
2740:
2737:
2735:
2732:
2731:
2730:
2727:
2725:
2722:
2720:
2717:
2715:
2712:
2710:
2707:
2705:
2703:
2700:
2699:
2696:
2695:Wound healing
2693:
2691:
2688:
2686:
2683:
2679:
2676:
2675:
2674:
2671:
2667:
2664:
2662:
2659:
2657:
2654:
2652:
2649:
2648:
2647:
2644:
2643:
2641:
2637:
2633:
2626:
2621:
2619:
2614:
2612:
2607:
2606:
2603:
2591:
2588:
2584:
2581:
2579:
2576:
2574:
2571:
2569:
2566:
2565:
2563:
2559:
2556:
2554:
2551:
2550:
2548:
2547:
2545:
2543:
2539:
2531:
2528:
2526:
2523:
2521:
2518:
2516:
2513:
2512:
2510:
2509:
2507:
2505:
2501:
2497:
2493:
2486:
2481:
2479:
2474:
2472:
2467:
2466:
2463:
2450:
2446:
2445:
2441:
2439:
2436:
2433:
2430:
2427:
2424:
2420:
2419:
2415:
2413:
2409:
2408:
2404:
2403:
2400:
2396:
2389:
2385:
2384:
2380:
2378:
2374:
2373:
2369:
2367:
2363:
2362:
2358:
2356:
2352:
2348:
2347:
2343:
2339:
2337:
2333:
2329:
2325:
2321:
2320:
2316:
2312:
2310:
2306:
2305:
2301:
2297:
2296:
2293:
2288:
2284:
2277:
2272:
2268:
2267:
2253:
2239:
2232:
2225:
2224:
2218:
2210:
2206:
2202:
2198:
2193:
2188:
2184:
2180:
2176:
2169:
2161:
2154:
2148:
2142:
2127:
2126:The Spectator
2123:
2116:
2100:
2096:
2090:
2082:
2078:
2073:
2068:
2064:
2060:
2059:
2054:
2047:
2036:
2030:
2022:
2018:
2014:
2008:
2000:
1996:
1992:
1988:
1984:
1980:
1973:
1965:
1961:
1957:
1953:
1950:(2): 166–75.
1949:
1945:
1938:
1923:
1917:
1911:
1907:
1906:
1900:
1892:
1888:
1883:
1878:
1874:
1870:
1866:
1859:
1851:
1847:
1843:
1839:
1836:(4): 755–75.
1835:
1831:
1824:
1816:
1812:
1808:
1804:
1800:
1796:
1793:(2): 519–28.
1792:
1788:
1787:Radiographics
1781:
1773:
1767:
1763:
1762:
1754:
1738:
1734:
1727:
1712:
1708:
1702:
1687:
1683:
1677:
1669:
1665:
1661:
1657:
1653:
1649:
1642:
1634:
1630:
1626:
1622:
1618:
1614:
1611:(5): 569–74.
1610:
1606:
1605:
1600:
1593:
1585:
1581:
1576:
1571:
1567:
1563:
1559:
1555:
1551:
1544:
1542:
1533:
1529:
1525:
1521:
1516:
1511:
1507:
1503:
1500:(4): 466–72.
1499:
1495:
1491:
1484:
1476:
1470:
1466:
1459:
1451:
1447:
1442:
1437:
1433:
1429:
1425:
1421:
1417:
1409:
1401:
1397:
1392:
1387:
1384:(4): 355–69.
1383:
1379:
1375:
1367:
1359:
1355:
1350:
1345:
1341:
1337:
1332:
1327:
1323:
1319:
1315:
1308:
1306:
1304:
1302:
1300:
1298:
1296:
1294:
1278:
1276:9780702072109
1272:
1268:
1267:
1259:
1251:
1245:
1241:
1234:
1226:
1222:
1219:(2): 314–17.
1218:
1214:
1207:
1199:
1195:
1190:
1185:
1181:
1177:
1173:
1169:
1165:
1158:
1156:
1147:
1143:
1138:
1133:
1129:
1125:
1122:(6): 349–57.
1121:
1117:
1113:
1106:
1090:
1086:
1080:
1065:
1061:
1055:
1053:
1051:
1049:
1047:
1030:
1026:
1020:
1018:
1016:
1014:
997:
993:
987:
985:
983:
981:
979:
977:
960:
956:
950:
948:
946:
929:
925:
919:
917:
915:
913:
911:
909:
907:
902:
894:
893:of tissues".
892:
887:
883:
880:and from the
878:
873:
869:
859:
857:
853:
849:
844:
842:
838:
834:
832:
827:
825:
821:
817:
816:
811:
808:
803:
801:
797:
792:
788:
784:
776:
772:
763:
761:
757:
753:
751:
742:
740:
736:
731:
728:
726:
721:
717:
715:
710:
700:
697:
693:
692:fibrinolytics
689:
688:anticoagulant
685:
681:
676:
666:
658:
647:
643:
639:
636:
632:
628:
625:
621:
617:
614:
611:
608:
605:
602:
601:
595:
592:
591:
585:
583:
579:
574:
572:
568:
567:
562:
557:
555:
551:
547:
543:
542:
535:
525:
523:
519:
514:
512:
511:
506:
505:
500:
496:
487:
478:
475:
471:
469:
465:
461:
457:
453:
448:
446:
441:
437:
433:
429:
425:
421:
418:
414:
404:
402:
398:
388:
381:
372:
370:
366:
362:
358:
354:
350:
346:
341:
339:
335:
331:
327:
323:
319:
315:
311:
307:
303:
299:
298:hypernatremia
295:
291:
287:
283:
279:
275:
271:
267:
263:
259:
255:
251:
246:
244:
240:
236:
232:
229:is a type of
228:
219:
215:
211:
209:
205:
201:
197:
193:
191:
187:
184:
180:
176:
172:
168:
164:
160:
156:
152:
149:
147:
143:
140:
136:
132:
128:
124:
121:
117:
114:
110:
107:
105:
104:Complications
101:
97:
95:
91:
88:
84:
80:
77:
75:
71:
68:
63:
59:
54:
50:
46:
41:
33:
19:
4007:Malakoplakia
3974:
3933:Folliculitis
3857:Unspecified
3829:Lyme disease
3766:Helicobacter
3765:
3740:
3689:
3676:
3663:
3620:
3601:Gonococcemia
3512:
3492:Trench fever
3472:Scrub typhus
3412:
3333:
3325:
3317:
3277:Buruli ulcer
3246:
3221:
3191:Gas gangrene
3180:
3164:
3138:
3111:
3081:
2984:Enzyme assay
2830:
2825:
2814:Karyorrhexis
2790:Myocytolysis
2780:Fat necrosis
2769:
2685:Inflammation
2673:Hemodynamics
2666:Pathogenesis
2589:
2442:
2416:
2405:
2381:
2370:
2359:
2340:
2313:
2298:
2252:
2241:. Retrieved
2231:
2222:
2217:
2182:
2178:
2168:
2153:
2141:
2129:. Retrieved
2125:
2115:
2103:. Retrieved
2098:
2089:
2062:
2056:
2046:
2029:
2016:
2007:
1982:
1978:
1972:
1947:
1943:
1937:
1925:. Retrieved
1916:
1903:
1899:
1872:
1868:
1858:
1833:
1829:
1823:
1790:
1786:
1780:
1760:
1753:
1741:. Retrieved
1736:
1726:
1715:. Retrieved
1713:. 2019-02-21
1710:
1701:
1689:. Retrieved
1685:
1676:
1659:
1655:
1651:
1641:
1608:
1602:
1598:
1592:
1557:
1553:
1497:
1493:
1483:
1464:
1458:
1423:
1419:
1408:
1381:
1377:
1366:
1321:
1317:
1280:. Retrieved
1265:
1258:
1239:
1233:
1216:
1212:
1206:
1171:
1167:
1119:
1115:
1105:
1093:. Retrieved
1088:
1079:
1067:. Retrieved
1063:
1033:. Retrieved
1028:
1000:. Retrieved
995:
963:. Retrieved
959:patient.info
958:
932:. Retrieved
927:
891:putrefaction
865:
845:
835:
829:French King
828:
813:
804:
780:
754:
748:
732:
729:
722:
718:
706:
672:
664:
656:
598:
575:
571:streptococci
564:
558:
549:
539:
537:
534:Gas gangrene
528:Gas gangrene
515:
508:
502:
492:
481:Wet gangrene
472:
449:
440:putrefaction
423:
410:
407:Dry gangrene
394:
386:
342:
326:gas gangrene
322:wet gangrene
318:dry gangrene
282:dengue fever
262:major trauma
247:
233:caused by a
231:tissue death
226:
225:
163:major trauma
146:Risk factors
18:Wet gangrene
4012:Pyomyositis
3720:Shigellosis
3690:Pseudomonas
3614:Melioidosis
3580:Oroya fever
3570:Brucellosis
3402:Nocardiosis
3212:Listeriosis
3182:Clostridium
2838:Hemosiderin
2719:Hyperplasia
2714:Hypertrophy
2690:Cell damage
2558:Hemorrhagic
2407:MedlinePlus
1711:www.cdc.gov
1652:Clostridium
1420:Circulation
1324:: 255–264.
1095:12 December
1069:12 December
1035:12 December
1002:12 December
965:12 December
934:12 December
805:The French
696:antibiotics
588:Other types
566:Bacteroides
548:-producing
546:alpha toxin
541:Clostridium
365:angioplasty
349:debridement
345:antibiotics
48:Other names
4057:Categories
3900:Paronychia
3895:Cellulitis
3768:cellulitis
3679:cellulitis
3619:Cutaneous
3223:Mycoplasma
3173:Erythrasma
3146:Erysipelas
3137:Cutaneous
3004:Blood bank
2847:Lipofuscin
2843:Lipochrome
2819:Karyolysis
2748:Cell death
2729:Metaplasia
2542:Infarction
2496:infarction
2444:Patient UK
2372:DiseasesDB
2243:2014-04-15
1985:: S6–S13.
1717:2019-08-05
1025:"Gangrene"
955:"Gangrene"
897:References
848:Union Army
775:Union Army
669:Medication
624:thrombosis
499:saprogenic
353:amputation
290:chickenpox
266:alcoholism
167:alcoholism
113:amputation
3890:Carbuncle
3743:infection
3741:Aeromonas
3735:Chancroid
3659:Tularemia
3623:infection
3605:Gonorrhea
3515:infection
3415:infection
3336:infection
3328:infection
3320:infection
3141:infection
3073:Bacillota
2859:Steatosis
2802:Apoptosis
2739:Glandular
2724:Dysplasia
2656:Neoplasia
2651:Infection
2632:Pathology
2564:Location
2511:Location
2492:Ischaemia
2418:eMedicine
2388:372070002
2383:SNOMED CT
1910:eMedicine
1648:Chuang YC
1340:1178-7007
886:gangraina
877:gangraena
868:etymology
862:Etymology
852:mortality
831:Louis XIV
824:amputated
661:Lifestyle
653:Treatment
495:prognosis
456:infection
278:influenza
274:frostbite
217:Frequency
208:Prognosis
199:Treatment
179:frostbite
74:Specialty
4078:Necrosis
4063:Gangrene
3975:Gangrene
3926:Pyoderma
3859:pathogen
3789:Syphilis
3784:Syphilid
3633:Glanders
3438:Gram -ve
3122:Impetigo
3097:Impetigo
3064:Gram +ve
3014:Serology
2809:Pyknosis
2755:Necrosis
2734:Squamous
2678:Ischemia
2590:Gangrene
2504:Ischemia
2449:Gangrene
2276:Gangrene
2209:26732207
2201:21944621
2131:12 March
2105:March 7,
2081:24841930
2065:: 32–7.
1999:25478859
1964:23374620
1927:July 24,
1891:10575138
1850:20659659
1807:18349455
1743:5 August
1739:. cfpmfc
1633:12940936
1625:15632295
1584:24715679
1524:22694053
1450:27840333
1400:24486336
1358:29910628
1225:22216805
1198:26631369
1146:19008688
800:efficacy
709:debrided
680:ischemia
561:exotoxin
468:emergent
454:without
452:ischemia
417:ischemic
401:diabetes
270:HIV/AIDS
250:diabetes
227:Gangrene
212:Variable
175:HIV/AIDS
151:Diabetes
135:internal
94:Symptoms
87:podiatry
43:Gangrene
3955:Ecthyma
3866:Abscess
3794:Chancre
3710:Q fever
3297:Leprosy
3249:related
2887:Autopsy
2852:Melanin
2832:pigment
2709:Atrophy
2646:Disease
2366:D005734
2179:Am Surg
2017:fda.gov
1815:2930176
1691:22 July
1668:8541740
1575:7154343
1532:5693425
1515:7950796
1441:5477786
1349:5987754
1282:8 April
1189:8652263
1137:2743684
856:bromide
815:Te Deum
787:maggots
766:History
703:Surgery
640:Severe
629:Severe
578:toxemia
286:malaria
258:smoking
220:Unknown
159:smoking
83:surgery
3950:Pimple
3725:Plague
3390:Others
3205:Others
2578:Spleen
2553:Anemic
2549:Types
2412:007218
2226:. 1863
2207:
2199:
2079:
2019:. US:
1997:
1962:
1889:
1848:
1813:
1805:
1768:
1666:
1631:
1623:
1582:
1572:
1530:
1522:
1512:
1471:
1448:
1438:
1398:
1356:
1346:
1338:
1273:
1246:
1223:
1196:
1186:
1144:
1134:
791:ulcers
735:tibial
690:, and
420:tissue
391:Causes
332:, and
294:plague
243:sepsis
171:plague
109:Sepsis
3809:Bejel
3804:Pinta
3777:Other
3647:Gamma
3455:Alpha
2661:Cause
2573:Brain
2568:Heart
2520:Heart
2515:Brain
2377:19273
2355:785.4
2351:040.0
2336:I73.9
2332:E10.2
2328:I70.2
2205:S2CID
2038:(PDF)
1811:S2CID
1629:S2CID
1528:S2CID
882:Greek
874:word
872:Latin
820:baton
783:flies
745:Other
582:shock
239:fever
119:Types
3799:Yaws
3594:Beta
2583:Limb
2494:and
2361:MeSH
2346:9-CM
2309:MC85
2197:PMID
2133:2017
2107:2017
2077:PMID
1995:PMID
1960:PMID
1929:2013
1887:PMID
1846:PMID
1803:PMID
1766:ISBN
1745:2024
1693:2021
1664:PMID
1621:PMID
1580:PMID
1520:PMID
1469:ISBN
1446:PMID
1396:PMID
1354:PMID
1336:ISSN
1284:2020
1271:ISBN
1244:ISBN
1221:PMID
1194:PMID
1172:2015
1142:PMID
1097:2017
1071:2017
1037:2017
1004:2017
967:2017
936:2017
866:The
785:and
737:and
622:and
607:Noma
580:and
312:and
2342:ICD
2334:,
2330:,
2326:,
2324:R02
2315:ICD
2300:ICD
2187:doi
2067:doi
1987:doi
1952:doi
1908:at
1877:doi
1838:doi
1795:doi
1613:doi
1609:136
1570:PMC
1562:doi
1510:PMC
1502:doi
1436:PMC
1428:doi
1424:135
1386:doi
1344:PMC
1326:doi
1184:PMC
1176:doi
1132:PMC
1124:doi
1089:NHS
1064:NHS
1029:NHS
996:NHS
928:NHS
507:or
424:dry
363:or
241:or
131:gas
127:wet
123:Dry
4059::
3902:/
3702:/
3698:/
3694:/
3687:/
3148:/
2447::
2421::
2410::
2386::
2375::
2364::
2353:,
2349::
2322::
2319:10
2307::
2304:11
2203:.
2195:.
2183:77
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