407:
60:
837:. There have been two SNPs in CTLA-4 that were found to be significantly associated with childhood allergic rhinitis. Both SNPs most likely affect the associated protein's shape and function, causing the body to exhibit an overactive immune response to the posed allergen. The polymorphisms in both genes are only beginning to be examined, therefore more research is needed to determine the severity of the impact of polymorphisms in the respective genes.
866:
6447:
1234:), thereby inducing specific long-term tolerance. Allergen immunotherapy is the only treatment that alters the disease mechanism. Immunotherapy can be administered orally (as sublingual tablets or sublingual drops), or by injections under the skin (subcutaneous). Subcutaneous immunotherapy is the most common form and has the largest body of evidence supporting its effectiveness.
857:
repress parts of the body's immune and inflammatory responses, thus contributing to the pathogenesis of allergic rhinitis and other autoimmune disorders. There are many miRNAs that have been deemed potential therapeutic targets for the treatment of allergic rhinitis by many different researchers, with the most widely studied being miR-133, miR-155, miR-205, miR-498, and let-7e.
1066:, relief from symptoms is experienced within 15 minutes allowing for a more immediate 'as-needed' approach to dosage. There is not enough evidence of antihistamine efficacy as an add-on therapy with nasal steroids in the management of intermittent or persistent allergic rhinitis in children, so its adverse effects and additional costs must be considered.
280:, red, itchy, and watery eyes, and swelling around the eyes. The fluid from the nose is usually clear. Symptom onset is often within minutes following allergen exposure, and can affect sleep and the ability to work or study. Some people may develop symptoms only during specific times of the year, often as a result of
3451:
1250:
is not supported by available evidence. While some evidence shows that acupuncture is effective for rhinitis, specifically targeting the sphenopalatine ganglion acupoint, these trials are still limited. Overall, the quality of evidence for complementary-alternative medicine is not strong enough to be
945:
Allergic rhinitis may also be classified as mild-intermittent, moderate-severe intermittent, mild-persistent, and moderate-severe persistent. Intermittent is when the symptoms occur <4 days per week or <4 consecutive weeks. Persistent is when symptoms occur >4 days/week and >4 consecutive
941:
Allergic rhinitis may be seasonal, perennial, or episodic. Seasonal allergic rhinitis occurs in particular during pollen seasons. It does not usually develop until after 6 years of age. Perennial allergic rhinitis occurs throughout the year. This type of allergic rhinitis is commonly seen in younger
891:
Allergy testing is not definitive. At times, these tests can reveal positive results for certain allergens that are not actually causing symptoms, and can also not pick up allergens that do cause an individual's symptoms. The intradermal allergy test is more sensitive than the skin prick test, but is
879:
to determine if a particular substance is causing the rhinitis, or an intradermal, scratch, or other test. Less commonly, the suspected allergen is dissolved and dropped onto the lower eyelid as a means of testing for allergies. This test should be done only by a physician, since it can be harmful if
464:
occurs. For example, people allergic to birch pollen may also find that they have an allergic reaction to the skin of apples or potatoes. A clear sign of this is the occurrence of an itchy throat after eating an apple or sneezing when peeling potatoes or apples. This occurs because of similarities in
1828:
With respect to what is termed the exciting cause of the disease, since the attention of the public has been turned to the subject an idea has very generally prevailed, that it is produced by the effluvium from new hay, and it has hence obtained the popular name of hay fever. the effluvium from hay
856:
have been found to play a role in the body's immune and inflammatory responses to allergens. miRNAs are housed and packaged inside of exosomes until they are ready to be released into the section of the cell that they are coded to reside and act. Repressing the translation of proteins can ultimately
1004:
Prevention often focuses on avoiding specific allergens that cause an individual's symptoms. These methods include not having pets, not having carpets or upholstered furniture in the home, and keeping the home dry. Specific anti-allergy zippered covers on household items like pillows and mattresses
977:
The symptoms of local allergic rhinitis are the same as the symptoms of allergic rhinitis, including symptoms in the eyes. Just as with allergic rhinitis, people can have either seasonal or perennial local allergic rhinitis. The symptoms of local allergic rhinitis can be mild, moderate, or severe.
820:
of the T cells. As mentioned earlier, T cells contribute to the body's inflammatory response in a variety of ways, so any changes to the cells' structure and function can have potentially deleterious effects on the body's inflammatory response to allergens. To date, one SNP in the PTPN22 gene has
1110:
is also indicated for vasomotor rhinitis. It is used only when nasal congestion is present and can be used with antihistamines. In the United States, oral decongestants containing pseudoephedrine must be purchased behind the pharmacy counter in an effort to prevent the manufacturing of
792:
of the IL-33 gene and their link to allergic rhinitis within the Han
Chinese population, researchers found that five SNPs specifically contributed to the pathogenesis of allergic rhinitis, with three of those five SNPs previously identified as genetic determinants for asthma.
946:
weeks. The symptoms are considered mild with normal sleep, no impairment of daily activities, no impairment of work or school, and if symptoms are not troublesome. Severe symptoms result in sleep disturbance, impairment of daily activities, and impairment of school or work.
821:
been found to be significantly associated with allergic rhinitis onset in children. On the other hand, CTLA-4 is an immune-checkpoint protein that helps mediate and control the body's immune response to prevent overactivation. It is expressed only in T cells as a
2432:
Baumann R, Rabaszowski M, Stenin I, Tilgner L, Gaertner-Akerboom M, Scheckenbach K, Wiltfang J, Chaker A, Schipper J, Wagenmann M (2013). "Nasal Levels of
Soluble IL-33R ST2 and IL-16 in Allergic Rhinitis: Inverse Correlation Trends with Disease Severity".
787:
and had a higher concentration of ST2 serum in nasal passageways following their exposure to pollen and other allergens, indicating that this gene and its associated receptor are expressed at a higher rate in allergic rhinitis patients. In a 2020 study on
377:
that affects the greatest number of people. In
Western countries, between 10 and 30% of people are affected in a given year. It is most common between the ages of twenty and forty. The first accurate description is from the 10th-century physician
754:(GWAS) have identified a number of different loci and genetic pathways that seem to mediate the body's response to allergens and promote the development of allergic rhinitis, with some of the most promising results coming from studies involving
1221:
Nasal saline irrigation (a practice where salt water is poured into the nostrils), may have benefits in both adults and children in relieving the symptoms of allergic rhinitis and it is unlikely to be associated with adverse effects.
2597:
Suojalehto H, Toskala E, Kilpeläinen M, Majuri ML, Mitts C, Lindström I, Puustinen A, Plosila T, Sipilä J, Wolff H, Alenius H (2013). "MicroRNA Profiles in Nasal Mucosa of
Patients with Allergic and Nonallergic Rhinitis and Asthma".
465:
the proteins of the pollen and the food. There are many cross-reacting substances. Hay fever is not a true fever, meaning it does not cause a core body temperature in the fever over 37.5–38.3 °C (99.5–100.9 °F).
598:). In northern latitudes, birch is considered to be the most common allergenic tree pollen, with an estimated 15–20% of people with hay fever sensitive to birch pollen grains. A major antigen in these is a protein called
496:
season. However, it is possible to have allergic rhinitis throughout the year. The pollen that causes hay fever varies between individuals and from region to region; in general, the tiny, hardly visible pollens of
6328:
6313:
1011:
Studies in young children have shown that there is higher risk of allergic rhinitis in those who have early exposure to foods or formula or heavy exposure to cigarette smoking within the first year of life.
1130:
are effective and safe, and may be effective without oral antihistamines. They take several days to act and so must be taken continually for several weeks, as their therapeutic effect builds up with time.
778:
pathogenesis, and because of the pathological linkage between asthma and rhinitis, the experimental focus of IL-33 has now turned to its role in the development of allergic rhinitis in humans and mouse
3522:
Passalacqua G, Bousquet PJ, Carlsen KH, Kemp J, Lockey RF, Niggemann B, et al. (May 2006). "ARIA update: I—Systematic review of complementary and alternative medicine for rhinitis and asthma".
370:, is often effective. The allergen can be given as an injection under the skin or as a tablet under the tongue. Treatment typically lasts three to five years, after which benefits may be prolonged.
3247:
Karaki M, Akiyama K, Mori N (June 2013). "Efficacy of intranasal steroid spray (mometasone furoate) on treatment of patients with seasonal allergic rhinitis: comparison with oral corticosteroids".
2321:
2292:
445:
There can also be behavioral signs; in order to relieve the irritation or flow of mucus, people may wipe or rub their nose with the palm of their hand in an upward motion: an action known as the "
1195:
may also be helpful in reducing symptoms such as nasal congestion, but should not be used for long periods, as stopping them after protracted use can lead to a rebound nasal congestion called
996:
As of 2014, local allergenic rhinitis had mostly been investigated in Europe; in the United States, the nasal provocation testing necessary to diagnose the condition was not widely available.
1267:
that affects the greatest number of people. In
Western countries, between 10 and 30 percent of people are affected in a given year. It is most common between the ages of twenty and forty.
442:, and middle ear effusion. Nasal endoscopy may show findings such as pale and boggy inferior turbinates from mucosal edema, stringy mucus throughout the nasal cavities, and cobblestoning.
2722:
1020:
The goal of rhinitis treatment is to prevent or reduce the symptoms caused by the inflammation of affected tissues. Measures that are effective include avoiding the allergen. Intranasal
3721:
3687:
1230:
Allergen immunotherapy, also called desensitization, treatment involves administering doses of allergens to accustom the body to substances that are generally harmless (pollen,
307:
and environmental exposures contribute to the development of allergies. Growing up on a farm and having multiple siblings decreases this risk. The underlying mechanism involves
3635:
Witt CM, Brinkhaus B (October 2010). "Efficacy, effectiveness and cost-effectiveness of acupuncture for allergic rhinitis – An overview about previous and ongoing studies".
2933:
RondĂłn C, Campo P, Galindo L, Blanca-LĂłpez N, Cassinello MS, Rodriguez-Bada JL, et al. (October 2012). "Prevalence and clinical relevance of local allergic rhinitis".
319:. It causes mucous membranes in the nose, eyes and throat to become inflamed and itchy as they work to eject the allergen. Diagnosis is typically based on a combination of
3758:
742:
The causes and pathogenesis of allergic rhinitis are hypothesized to be affected by both genetic and environmental factors, with many recent studies focusing on specific
5100:
4108:
1165:) injection are effective at reducing nasal inflammation, but their use is limited by their short duration of effect and the side-effects of prolonged steroid therapy.
3215:
366:. Oftentimes, medications do not completely control symptoms, and they may also have side effects. Exposing people to larger and larger amounts of allergen, known as
875:
Allergy testing may reveal the specific allergens to which an individual is sensitive. Skin testing is the most common method of allergy testing. This may include a
476:
Predisposing factors to allergic rhinitis include eczema (atopic dermatitis) and asthma. These three conditions can often occur together which is referred to as the
398:
with hay is accurate, as peak hay-harvesting season overlaps with peak pollen season, and hay-harvesting work puts people in close contact with seasonal allergens.
1295:
with hay checks out, as peak hay-harvesting season overlaps with peak pollen season, and hay-harvesting work puts people in close contact with seasonal allergens.
1242:
There are no forms of complementary or alternative medicine that are evidence-based for allergic rhinitis. Therapeutic efficacy of alternative treatments such as
2862:
2185:
1142:
oral tablets for the treatment of people with seasonal allergic rhinitis and found that the two have virtually equivalent effects on nasal symptoms in people.
993:
were found to actually have local allergic rhinitis. Steroid nasal sprays and oral antihistamines have been found to be effective for local allergic rhinitis.
1555:
1659:
1291:
came about due to an early (and incorrect) theory that the symptoms were brought about by the smell of new hay. Although the scent per se is irrelevant, the
453:". This may result in a crease running across the nose (or above each nostril if only one side of the nose is wiped at a time), commonly referred to as the "
394:
came about due to an early (and incorrect) theory that the symptoms were brought about by the smell of new hay. Although the scent per se is irrelevant, the
1516:
774:, on these cells bind to the ligand IL-33 protein. This IL-33/ST2 signaling pathway has been found to be one of the main genetic determinants in bronchial
2343:
Kamekura R, Kojima T, Takano K, Go M, Sawada N, Himi T (2012). "The Role of IL-33 and Its
Receptor ST2 in Human Nasal Epithelium with Allergic Rhinitis".
1483:
6472:
1327:
1252:
480:. Additionally, environmental exposures such as air pollution and maternal tobacco smoking can increase an individual's chances of developing allergies.
3586:"Effectiveness of Acupuncturing at the Sphenopalatine Ganglion Acupoint Alone for Treatment of Allergic Rhinitis: A Systematic Review and Meta-Analysis"
3415:
Van
Overtvelt L, Batard T, Fadel R, Moingeon P (December 2006). "Mécanismes immunologiques de l'immunothérapie sublinguale spécifique des allergènes".
3282:
Ohlander BO, Hansson RE, Karlsson KE (1980). "A comparison of three injectable corticosteroids for the treatment of patients with seasonal hay fever".
1448:
1062:
It is best to take oral antihistamine medication before exposure, especially for seasonal allergic rhinitis. In the case of nasal antihistamines like
2527:"Single-nucleotide polymorphisms and haplotypes in the interleukin-33 gene are associated with a risk of allergic rhinitis in the Chinese population"
2478:"Single-Nucleotide Polymorphisms and Haplotypes in the Interleukin-33 Gene Are Associated with a Risk of Allergic Rhinitis in the Chinese Population"
327:
or blood tests for allergen-specific IgE antibodies. These tests, however, can give false positives. The symptoms of allergies resemble those of the
2692:
Xiao L, Jiang L, Hu Q, Li Y. "MicroRNA-133b
Ameliorates Allergic Inflammation and Symptom in Murine Model of Allergic Rhinitis by Targeting NIrp3".
4587:
3751:
4719:
4101:
2718:
1008:
Studies have shown that growing up on a farm and having many older siblings can decrease an individual's risk for developing allergic rhinitis.
2582:
Song SH, Wang XQ, Shen Y, Hong SL, Ke, X. "Association between PTPN22/CTLA-4 Gene
Polymorphism and Allergic Rhinitis with Asthma in Children".
2239:
989:
In one study, about 25% of people with rhinitis had local allergic rhinitis. In several studies, over 40% of people having been diagnosed with
5564:
3804:
3443:
5814:
1705:
3744:
3113:
3023:
1943:
1815:
3683:
2836:
1747:
1024:
are the preferred medical treatment for persistent symptoms, with other options if this is not effective. Second line therapies include
4094:
804:) gene can be associated with childhood allergic rhinitis and allergic asthma. The encoded PTPN22 protein, which is found primarily in
5319:
4670:
4665:
4266:
3044:
Akhouri S, House SA. Allergic
Rhinitis. . In: StatPearls . Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from:
2100:
Czaja-Bulsa G, BachĂłrska J (December 1998). "" [Food allergy in children with pollinosis in the Western sea coast region].
1957:
Ziade, Georges K.; Karami, Reem A.; Fakhri, Ghina B.; Alam, Elie S.; Hamdan, Abdul latif; Mourad, Marc M.; Hadi, Usama M. (2016).
5343:
5115:
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844:
alterations and associations are of particular interest to the study and ultimate treatment of allergic rhinitis. Specifically,
4443:
6261:
5090:
2219:
1635:
2993:
2765:
RondĂłn C, Canto G, Blanca M (February 2010). "Local allergic rhinitis: a new entity, characterization and further studies".
1860:
1048:-proof covers, air filters, and withholding certain foods in childhood do not have evidence supporting their effectiveness.
796:
Another study focusing on Han Chinese children found that certain SNPs in the protein tyrosine phosphatase non-receptor 22 (
3048:
338:
Exposure to animals early in life might reduce the risk of developing these specific allergies. Several different types of
2748:
2191:
1908:
1126:
corticosteroids are used to control symptoms associated with sneezing, rhinorrhea, itching, and nasal congestion. Steroid
6343:
5776:
5559:
5314:
4712:
3137:"Antihistamines used in addition to topical nasal steroids for intermittent and persistent allergic rhinitis in children"
516:
plants are too large to remain airborne and pose no risk. Examples of plants commonly responsible for hay fever include:
6234:
5569:
5365:
3198:
2084:
1769:
5766:
5546:
5046:
4741:
4736:
4660:
4438:
2987:
2315:
2286:
2270:
1854:
1741:
1699:
1059:
drugs can be taken orally and nasally to control symptoms such as sneezing, rhinorrhea, itching, and conjunctivitis.
3727:
3189:
May JR, Smith PH (2008). "Allergic Rhinitis". In DiPiro JT, Talbert RL, Yee GC, Matzke G, Wells B, Posey LM (eds.).
2858:
1077:) are used for conjunctivitis, while intranasal forms are used mainly for sneezing, rhinorrhea, and nasal pruritus.
6477:
6278:
5807:
4297:
2076:
1563:
1037:
770:. Th2 cells contribute to the body's inflammatory response to allergens, and specific ST2 receptors, also known as
359:
233:
1651:
5510:
4479:
4341:
1182:
1093:
849:
755:
751:
4433:
3327:"Oxymetazoline adds to the effectiveness of fluticasone furoate in the treatment of perennial allergic rhinitis"
1524:
5781:
5247:
4705:
1491:
1085:
4336:
1335:
6226:
5355:
4559:
1112:
473:
Pollen is often considered as a cause of allergic rhinitis, hence called hay fever (See sub-section below).
331:; however, they often last for more than two weeks and, despite the common name, typically do not include a
6238:
6118:
5554:
5505:
5338:
5276:
4616:
3916:
3794:
1456:
954:
Local allergic rhinitis is an allergic reaction in the nose to an allergen, without systemic allergies. So
5800:
5515:
4518:
4321:
3857:
880:
done improperly. In some individuals not able to undergo skin testing (as determined by the doctor), the
783:. Recently, it was found that allergic rhinitis patients expressed higher levels of IL-33 in their nasal
3684:"Sublingual Immunotherapy (SLIT) Allergy Tablets - American Academy of Allergy, Asthma & Immunology"
6437:
6242:
6230:
6036:
5701:
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4227:
903:
for allergies, they may still have allergic rhinitis, from a local allergy in the nose. This is called
762:(IL-33) gene. The IL-33 protein that is encoded by the IL-33 gene is part of the interleukin family of
299:
Allergic rhinitis is typically triggered by environmental allergens such as pollen, pet hair, dust, or
31:
6222:
5574:
5199:
5173:
4898:
4799:
4579:
4402:
3819:
2976:
Flint PW, Haughey BH, Robbins KT, Thomas JR, Niparko JK, Lund VJ, Lesperance MM (November 28, 2014).
311:
that attach to an allergen, and subsequently result in the release of inflammatory chemicals such as
17:
2235:
852:
and repression of translation in their mRNA complement. Both miRNAs and their common carrier vessel
6354:
6246:
5792:
5350:
5178:
5163:
5156:
5061:
5022:
4969:
4947:
4905:
4833:
4493:
4262:
4248:
3921:
2884:
Bousquet J, Reid J, van Weel C, Baena Cagnani C, Canonica GW, Demoly P, et al. (August 2008).
1211:
5329:
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regulator by removing phosphate groups from targeted proteins. Importantly, PTPN22 can affect the
492:
of specific seasonal plants is commonly known as "hay fever", because it is most prevalent during
6266:
6097:
5478:
5120:
5036:
4911:
4366:
4129:
4065:
4026:
1154:
979:
454:
289:
163:
422:, sneezing fits, and nasal congestion and obstruction. Characteristic physical findings include
6179:
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5457:
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4044:
3903:
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431:
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241:
191:
117:
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3105:
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Zhang XH, Zhang YN, Liu Z (2014). "MicroRNA in Chronic Rhinosinusitis and Allergic Rhinitis".
1931:
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848:(miRNA) are hypothesized to be imperative to the pathogenesis of allergic rhinitis due to the
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4838:
2816:
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Yamamoto T, Asakura K, Shirasaki H, Himi T, Ogasawara H, Narita S, Kataura A (October 2005).
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4243:
4086:
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2212:"Urticaria, Angioedema, and Allergic Rhinitis." 'Harrison's Principles of Internal Medicine
2168:
Malandain H (September 2003). "" [Allergies associated with both food and pollen].
1192:
1044:. Antihistamines by mouth are suitable for occasional use with mild intermittent symptoms.
990:
5095:
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8:
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6213:
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5751:
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Head K, Snidvongs K, Glew S, Scadding G, Schilder AG, Philpott C, Hopkins C (June 2018).
1959:"Reliability assessment of the endoscopic examination in patients with allergic rhinitis"
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387:
339:
97:
85:
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3066:"Allergic rhinitis: definition, epidemiology, pathophysiology, detection, and diagnosis"
2015:
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1991:
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112:
73:
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2919:
2817:"Local allergic rhinitis: concept, clinical manifestations, and diagnostic approach"
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2031:
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Antihistamine drugs can have undesirable side-effects, the most notable one being
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Calderon MA, Alves B, Jacobson M, Hurwitz B, Sheikh A, Durham S (January 2007).
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also more often positive in people that do not have symptoms to that allergen.
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5983:
5874:
5827:
5823:
5663:
5616:
5001:
4953:
4822:
4523:
4313:
4195:
4184:
4060:
3981:
3971:
3941:
3931:
3926:
3656:
3621:
3602:
3570:
3543:
3508:
3444:"Subcutaneous immunotherapy for allergic disease: Indications and efficacy"
3401:
3352:
3268:
3227:
3170:
3091:
2954:
2911:
2832:
2786:
2678:
2619:
2568:
2511:
2454:
2410:
2364:
2181:
2154:
2113:
2057:
2000:
1974:
1904:
1609:
1419:
1174:
1097:
885:
822:
3303:
2542:
2493:
1796:"Dr. Marshall Hall on Diseases of the Respiratory System; III. Hay Asthma"
1401:
685:). An estimated 90% of people with hay fever are allergic to grass pollen.
6389:
6061:
6051:
6012:
5924:
5919:
5899:
5879:
5869:
5854:
5761:
5708:
5691:
5686:
5639:
5594:
5445:
5393:
5360:
5232:
4961:
4893:
4856:
4811:
4746:
4210:
4190:
4174:
3996:
3936:
3893:
2131:[Relationship between Pollen Allergy and Oral Allergy Syndrome].
2129:"[Relationship between pollen allergy and oral allergy syndrome]"
1292:
1243:
1127:
716:
513:
509:
423:
395:
386:
identified pollen as the cause. In 1906, the mechanism was determined by
363:
328:
237:
196:
154:
2525:
Ran, He; Xiao, Hua; Zhou, Xing; Guo, Lijun; Lu, Shuang (November 2020).
907:. Specialized testing is necessary to diagnose local allergic rhinitis.
884:
may be helpful in determining specific allergen sensitivity. Peripheral
59:
6418:
6158:
6138:
6133:
6128:
6087:
6046:
6017:
6007:
6002:
5978:
5934:
5894:
5681:
5281:
5267:
5242:
5217:
5212:
5146:
5017:
4993:
4942:
4816:
4781:
4756:
3867:
3837:
3325:
Baroody FM, Brown D, Gavanescu L, DeTineo M, Naclerio RM (April 2011).
1304:
1247:
1215:
1150:
1135:
1123:
1101:
1081:
1063:
876:
869:
841:
834:
784:
703:
505:
498:
415:
316:
211:
184:
6305:
3736:
2946:
2611:
2446:
6400:
6203:
6148:
6113:
5864:
5756:
5388:
5257:
5252:
5222:
4773:
3842:
3584:
Fu Q, Zhang L, Liu Y, Li X, Yang Y, Dai M, Zhang Q (March 12, 2019).
3557:
Terr AI (2004). "Unproven and controversial forms of immunotherapy".
1074:
959:
900:
845:
763:
410:
Illustration depicting inflammation associated with allergic rhinitis
312:
5822:
1652:"Allergic Rhinitis (Hay Fever): Symptoms, Diagnosis & Treatment"
1005:
have also proven to be effective in preventing dust mite allergies.
457:", and can lead to permanent physical deformity if repeated enough.
5949:
5771:
5656:
5056:
4789:
1588:
Dykewicz MS, Hamilos DL (February 2010). "Rhinitis and sinusitis".
1178:
1146:
1033:
967:
805:
698:
642:
582:
564:
558:
427:
419:
304:
277:
273:
265:
133:, red, itchy, and watery eyes, swelling around the eyes, itchy ears
130:
2596:
2314:
George Clinton Andrews; Anthony Nicholas Domonkos (July 1, 1998).
1275:
The first accurate description is from the 10th century physician
937:): Caused by allergens present throughout the year (e.g., dander).
865:
6153:
5009:
4885:
4133:
3767:
3475:"Allergen injection immunotherapy for seasonal allergic rhinitis"
3134:
2883:
1694:(4th ed.). Philadelphia, Pa.: W. B. Saunders. p. 1065.
1264:
707:
689:
670:
638:
576:
552:
374:
6348:
3414:
2821:
Journal of Investigational Allergology & Clinical Immunology
2643:"Novel Modulators of Asthma and Allergy: Exosomes and MicroRNAs"
2640:
504:
are the predominant cause. The study of the dispersion of these
6317:
5106:
4919:
4848:
4502:
3789:
3731:
2431:
1276:
983:
801:
797:
775:
771:
767:
675:
657:
649:
615:
546:
534:
489:
285:
281:
276:
in the air. Signs and symptoms include a runny or stuffy nose,
159:
68:
3521:
2932:
1849:. Karger Medical and Scientific Publishers. 2014. p. 62.
766:
that interact with T-helper 2 (Th2) cells, a specific type of
4927:
4469:
4137:
3135:
Nasser M, Fedorowicz Z, Aljufairi H, McKerrow W (July 2010).
722:
630:
602:. Olive pollen is most predominant in Mediterranean regions.
588:
570:
540:
522:
501:
477:
434:, lower eyelid venous stasis (rings under the eyes known as "
332:
4116:
3472:
3324:
2126:
923:): Caused by seasonal peaks in the airborne load of pollens.
4876:
2288:
Denver Medical Times: Utah Medical Journal. Nevada Medicine
1045:
661:
607:
594:
300:
2814:
3365:
3193:(7th ed.). New York: McGraw-Hill. pp. 1565–75.
2975:
2641:
Sastre B, Cañas JA, Rodrigo-Muñoz JM, del Pozo V (2017).
1288:
966:
antibodies produced in the nose that react to a specific
653:
493:
391:
3417:
Revue Française d'Allergologie et d'Immunologie Clinique
2214:(20th ed.). NY: McGraw-Hill. pp. Chapter 345.
800:) gene and cytotoxic T-lymphocyte-associated antigen 4 (
3281:
3214:
Craun, Kari L.; Patel, Preeti; Schury, Mark P. (2024),
284:
exposure. Many people with allergic rhinitis also have
4727:
2342:
2014:
La Mantia, Ignazio; Andaloro, Claudio (October 2017).
414:
The characteristic symptoms of allergic rhinitis are:
6435:
3590:
Evidence-Based Complementary and Alternative Medicine
2016:"Cobblestone Appearance of the Nasopharyngeal Mucosa"
1956:
1173:
Other measures that may be used second line include:
734:, which is in various fragrances and other products.
6295:
2979:
Cummings Otolaryngology–Head and Neck Surgery E-Book
2886:"Allergic rhinitis management pocket reference 2008"
2590:
2317:
Diseases of the Skin: For Practitioners and Students
2099:
1733:
Advice to the young physician on the art of medicine
5993:
mast cell stabilizer (some are also antihistamines)
2719:"American Academy of Allergy Asthma and Immunology"
730:Allergic rhinitis may also be caused by allergy to
71:
grains from a variety of common plants: sunflower (
2767:Current Opinion in Allergy and Clinical Immunology
2336:
2170:European Annals of Allergy and Clinical Immunology
1766:"John Bostock: The man who 'discovered' hay fever"
1253:American Academy of Allergy, Asthma and Immunology
3246:
2815:RondĂłn C, Fernandez J, Canto G, Blanca M (2010).
2764:
2584:Iranian Journal of Allergy, Asthma and Immunology
2575:
2425:
2013:
6459:
4588:Transfusion-associated graft-versus-host disease
3213:
2634:
2384:
2382:
2263:The Daily Telegraph: Complete Guide to Allergies
1763:
1279:. Pollen was identified as the cause in 1859 by
30:"Hay fever" redirects here. For other uses, see
3222:, Treasure Island (FL): StatPearls Publishing,
1929:
1587:
3524:The Journal of Allergy and Clinical Immunology
3331:The Journal of Allergy and Clinical Immunology
3070:The Journal of Allergy and Clinical Immunology
2685:
2524:
2475:
1590:The Journal of Allergy and Clinical Immunology
1443:
1441:
1439:
1437:
1435:
1433:
1431:
1429:
1383:
27:Nasal inflammation due to allergens in the air
5808:
4713:
4102:
3805:Eosinophilic granulomatosis with polyangiitis
3752:
3634:
3284:The Journal of International Medical Research
3046:https://www.ncbi.nlm.nih.gov/books/NBK538186/
2469:
2388:
2379:
2260:
1789:
1787:
1628:Current Diagnosis & Treatment: Pediatrics
1478:
1476:
1474:
888:can be seen in differential leukocyte count.
816:of T cell responses, and thus the subsequent
3583:
3318:
3191:Pharmacotherapy: A Pathophysiologic Approach
2600:International Forum of Allergy and Rhinology
2581:
1550:
1548:
1546:
1544:
1542:
1322:
1320:
904:
3479:The Cochrane Database of Systematic Reviews
3372:The Cochrane Database of Systematic Reviews
3184:
3182:
3180:
3141:The Cochrane Database of Systematic Reviews
2476:Ran H, Xiao H, Zhou X, Guo L, Lu S (2020).
1683:
1681:
1679:
1677:
1556:"Immunotherapy for Environmental Allergies"
1511:
1509:
1426:
1379:
1377:
1375:
1373:
1094:second- and third-generation antihistamines
1084:in the case of oral antihistamine tablets.
978:Local allergic rhinitis is associated with
6473:Steroid-responsive inflammatory conditions
5815:
5801:
4720:
4706:
4109:
4095:
3759:
3745:
1839:
1837:
1784:
1759:
1757:
1725:
1723:
1471:
1371:
1369:
1367:
1365:
1363:
1361:
1359:
1357:
1355:
1353:
1283:. In 1906 the mechanism was determined by
1134:In 2013, a study compared the efficacy of
949:
342:reduce allergic symptoms, including nasal
58:
5320:Combined pulmonary fibrosis and emphysema
3611:
3601:
3498:
3391:
3368:"Saline irrigation for allergic rhinitis"
3342:
3160:
3081:
2901:
2691:
2668:
2658:
2558:
2501:
2167:
2144:
2047:
1990:
1621:
1619:
1539:
1409:
1317:
1225:
1185:, and nonpharmacologic therapies such as
3188:
3177:
1932:"Allergic rhinitis: update on diagnosis"
1886:
1882:
1880:
1878:
1876:
1874:
1872:
1870:
1674:
1583:
1581:
1506:
1218:without risk of rhinitis medicamentosa.
962:for allergy are negative, but there are
864:
483:
405:
5344:Allergic bronchopulmonary aspergillosis
4622:Allergic bronchopulmonary aspergillosis
3810:Allergic bronchopulmonary aspergillosis
3766:
2760:
2758:
2307:
2279:
2254:
2064:
1834:
1754:
1750:from the original on September 8, 2017.
1720:
1687:
1350:
1237:
260:, of which the seasonal type is called
14:
6460:
3063:
3026:from the original on February 18, 2019
2865:from the original on February 19, 2015
2810:
2808:
2806:
2804:
2751:from the original on January 14, 2012.
2324:from the original on September 8, 2017
2295:from the original on September 8, 2017
2209:
1946:from the original on January 14, 2010.
1729:
1626:Covar R (2018). "Allergic Disorders".
1616:
1386:"Clinical practice. Allergic rhinitis"
1384:Wheatley LM, Togias A (January 2015).
5796:
4701:
4444:Post-streptococcal glomerulonephritis
4090:
3740:
2839:from the original on February 2, 2022
2827:(5): 364–71, quiz 2 p following 371.
2713:
2711:
2709:
2707:
2531:Experimental and Therapeutic Medicine
2238:. Forestry.about.com. March 5, 2014.
2205:
2203:
2201:
1867:
1625:
1578:
1517:"Environmental Allergies: Treatments"
401:
3556:
3441:
2755:
2073:Nonprescription Product Therapeutics
2070:
1793:
1484:"Environmental Allergies: Diagnosis"
1115:can also be used for this condition
1086:First-generation antihistamine drugs
1064:azelastine antihistamine nasal spray
5777:Idiopathic pulmonary haemosiderosis
3116:from the original on March 19, 2023
2801:
2242:from the original on April 14, 2014
1911:from the original on April 22, 2018
1863:from the original on June 10, 2016.
1829:has no connection with the disease.
1662:from the original on March 23, 2022
1390:The New England Journal of Medicine
1328:"Environmental Allergies: Symptoms"
1202:For nocturnal symptoms, intranasal
1069:Ophthalmic antihistamines (such as
488:Allergic rhinitis triggered by the
24:
5366:Vaping-associated pulmonary injury
4729:Diseases of the respiratory system
3690:from the original on March 3, 2022
3675:
3454:from the original on July 25, 2020
2996:from the original on July 25, 2020
2725:from the original on July 25, 2020
2704:
2198:
1887:Sur DK, Plesa ML (December 2015).
1818:from the original on July 25, 2020
1772:from the original on July 31, 2015
1736:. New York: Springer. p. 31.
1708:from the original on July 25, 2020
1630:(24th ed.). NY: McGraw-Hill.
1449:"Cause of Environmental Allergies"
737:
625:"Allergy friendly" trees include:
25:
6489:
4661:Autoimmune polyendocrine syndrome
3704:
2077:Lippincott Williams & Wilkins
1764:Justin Parkinson (July 1, 2014).
1263:Allergic rhinitis is the type of
1051:
910:
373:Allergic rhinitis is the type of
206:Exposure to animals early in life
149:Genetic and environmental factors
6445:
4298:Hemolytic disease of the newborn
2903:10.1111/j.1398-9995.2008.01642.x
2859:"Rush University Medical Center"
2357:10.1111/j.1365-2222.2011.03867.x
2020:The Eurasian Journal of Medicine
1930:Valet RS, Fahrenholz JM (2009).
1889:"Treatment of Allergic Rhinitis"
1523:. April 22, 2015. Archived from
1455:. April 22, 2015. Archived from
1334:. April 22, 2015. Archived from
1183:leukotriene receptor antagonists
1038:leukotriene receptor antagonists
360:leukotriene receptor antagonists
234:leukotriene receptor antagonists
4480:Subacute bacterial endocarditis
4342:Immune thrombocytopenic purpura
3628:
3577:
3559:Clinical Allergy and Immunology
3550:
3515:
3466:
3435:
3408:
3359:
3275:
3240:
3207:
3128:
3098:
3057:
3038:
3008:
2969:
2926:
2877:
2851:
2737:
2518:
2228:
2161:
2120:
2093:
2032:10.5152/eurasianjmed.2017.17257
2007:
1950:
1923:
1258:
1216:or an antihistamine nasal spray
850:post-transcriptional regulation
756:single-nucleotide polymorphisms
752:Genome-wide association studies
5826:and other nasal preparations (
5782:Pulmonary alveolar proteinosis
3491:10.1002/14651858.CD001936.pub2
3384:10.1002/14651858.CD012597.pub2
3153:10.1002/14651858.CD006989.pub2
3106:"Antihistamines for Allergies"
1691:Pediatric otolaryngology vol 2
1644:
1562:. May 12, 2015. Archived from
1490:. May 12, 2015. Archived from
895:Even if a person has negative
13:
1:
5356:Idiopathic pulmonary fibrosis
4560:Postorgasmic illness syndrome
2133:Nihon Jibiinkoka Gakkai Kaiho
1812:10.1016/S0140-6736(02)95895-2
1310:
1206:can be combined with nightly
1113:Desloratadine/pseudoephedrine
999:
931:nonseasonal allergic rhinitis
6119:Calcium hexamine thiocyanate
5339:Respiratory hypersensitivity
5277:Hypersensitivity pneumonitis
4617:Hypersensitivity pneumonitis
4045:Acute interstitial nephritis
3917:Eosinophilic gastroenteritis
3795:Hypersensitivity pneumonitis
3649:10.1016/j.autneu.2010.06.006
3429:10.1016/j.allerg.2006.10.006
2982:. Elsevier Health Sciences.
2779:10.1097/ACI.0b013e328334f5fb
1015:
860:
460:People might also find that
7:
5248:Coalworker's pneumoconiosis
4683:Systemic autoimmune disease
4519:Allergic contact dermatitis
4439:Hypersensitivity vasculitis
4322:Autoimmune hemolytic anemia
3858:Hypersensitivity vasculitis
3853:Allergic contact dermatitis
3536:10.1016/j.jaci.2005.12.1308
1298:
1118:
1071:azelastine in eye drop form
927:Perennial allergic rhinitis
183:, blood tests for specific
10:
6494:
6037:Beclometasone dipropionate
5101:Acute exacerbation of COPD
4189:common allergies include:
3344:10.1016/j.jaci.2011.01.037
3296:10.1177/030006058000800111
2146:10.3950/jibiinkoka.108.971
2102:Polski Merkuriusz Lekarski
1602:10.1016/j.jaci.2009.12.989
1270:
1153:tablets and intramuscular
917:Seasonal allergic rhinitis
418:(excess nasal secretion),
32:Hay fever (disambiguation)
29:
6380:
6299:
6256:
6192:
6172:
6106:
6027:
5954:excluding corticosteroids
5948:
5844:
5835:
5744:
5717:
5647:
5633:
5587:
5545:
5524:
5498:
5401:
5387:
5378:
5307:
5192:
5172:
5055:
5035:
4875:
4755:
4735:
4643:
4609:
4600:
4578:
4532:
4511:
4492:
4462:
4416:
4401:
4360:
4312:
4305:
4291:
4261:
4236:
4151:
4128:
4053:
4035:
4017:
3902:
3884:
3866:
3828:
3820:Laboratory animal allergy
3774:
3261:10.1016/j.anl.2012.09.004
2403:10.1007/s11882-013-0415-3
1893:American Family Physician
247:
210:
202:
190:
173:
153:
145:
137:
123:
111:
66:
57:
49:
44:
6107:Other nasal preparations
5164:Diffuse panbronchiolitis
5157:Bronchiolitis obliterans
5023:Laryngotracheal stenosis
4970:Laryngopharyngeal reflux
4948:Laryngopharyngeal reflux
4906:Laryngopharyngeal reflux
4834:Nasal septum perforation
4434:Henoch–Schönlein purpura
4249:Eosinophilic esophagitis
3922:Eosinophilic esophagitis
2660:10.3389/fimmu.2017.00826
2236:"Allergy Friendly Trees"
1212:adrenergic alpha-agonist
1168:
1092:cause drowsiness, while
972:Intradermal skin testing
746:that could be potential
673:): especially ryegrass (
468:
266:inflammation in the nose
251:~20% (Western countries)
67:SEM Microscope image of
6478:Type I hypersensitivity
6098:Triamcinolone acetonide
4912:Retropharyngeal abscess
4550:Hashimoto's thyroiditis
4337:Guillain–Barré syndrome
4066:Allergic conjunctivitis
4027:Eosinophilic meningitis
3868:Blood and immune system
3722:considered for deletion
3083:10.1067/mai.2001.115569
3064:Skoner DP (July 2001).
3051:March 18, 2022, at the
2391:Curr Allergy Asthma Rep
1963:Allergy & Rhinology
1794:Hall M (May 19, 1838).
1155:triamcinolone acetonide
950:Local allergic rhinitis
905:local allergic rhinitis
897:skin-prick, intradermal
606:is caused primarily by
455:transverse nasal crease
430:, eyelid swelling with
290:allergic conjunctivitis
164:allergic conjunctivitis
6180:Olopatadine/mometasone
6072:Fluticasone propionate
5605:Pulmonary hypertension
5334:Eosinophilic pneumonia
4986:Vocal cord dysfunction
4829:Nasal septum deviation
4651:Autoimmune adrenalitis
3800:Eosinophilic pneumonia
3637:Autonomic Neuroscience
2265:. Little, Brown Book.
2261:Pamela Brooks (2012).
1975:10.2500/ar.2016.7.0176
1596:(2 Suppl 2): S103-15.
1226:Allergen immunotherapy
1197:rhinitis medicamentosa
974:may also be negative.
872:
702:), nettle/parietaria (
411:
368:allergen immunotherapy
242:allergen immunotherapy
192:Differential diagnosis
118:Allergy and immunology
83:), prairie hollyhock (
5969:histamine antagonists
5732:Mediastinal emphysema
5511:Healthcare-associated
5441:Legionnaires' disease
4867:Peritonsillar abscess
4839:Nasal septal hematoma
2543:10.3892/etm.2020.9232
2494:10.3892/etm.2020.9232
1768:. BBC News Magazine.
1402:10.1056/NEJMcp1412282
1193:Topical decongestants
868:
520:Trees: such as pine (
484:Pollen-related causes
409:
268:that occurs when the
95:), evening primrose (
53:Hay fever, pollenosis
6173:Combination products
5479:Mendelson's syndrome
5351:Hamman–Rich syndrome
4656:Autoimmune hepatitis
4635:Transplant rejection
4545:Giant cell arteritis
4475:Rheumatoid arthritis
4332:Goodpasture syndrome
4244:Autoimmune urticaria
4037:Genitourinary system
3603:10.1155/2019/6478102
3249:Auris, Nasus, Larynx
1238:Alternative medicine
1104:are less likely to.
991:nonallergic rhinitis
720:), and sorrel/dock (
620:Chamaecyparis obtusa
612:Cryptomeria japonica
101:), and castor bean (
6235:+dexbrompheniramine
6214:Phenylpropanolamine
6144:Ipratropium bromide
6068:Fluticasone furoate
5752:Respiratory failure
5719:Mediastinal disease
5287:Bird fancier's lung
4862:Adenoid hypertrophy
4122:autoimmune diseases
3768:Allergic conditions
3022:. October 3, 2018.
2291:. January 1, 2010.
1285:Clemens von Pirquet
1251:recommended by the
748:therapeutic targets
562:), horse chestnut (
432:Dennie–Morgan folds
388:Clemens von Pirquet
179:Based on symptoms,
129:Stuffy itchy nose,
98:Oenothera fruticosa
86:Sidalcea malviflora
6381:External resources
6283:Never to phase III
6078:Mometasone furoate
5657:Pleuritis/pleurisy
5610:Pulmonary embolism
5506:Community-acquired
5431:Atypical bacterial
5330:Löffler's syndrome
5111:Status asthmaticus
5096:Chronic bronchitis
4981:Vocal fold paresis
4795:Vasomotor rhinitis
4565:Reactive arthritis
4555:Multiple sclerosis
4449:Reactive arthritis
4347:Pemphigus vulgaris
4327:Bullous pemphigoid
4228:Penicillin allergy
4164:Allergic urticaria
3886:Circulatory system
3776:Respiratory system
1846:History of Allergy
1688:Fireman P (2002).
1136:mometasone furoate
873:
810:post-translational
808:tissue, acts as a
712:Artemisia Vulgaris
679:sp.) and timothy (
604:Hay fever in Japan
412:
402:Signs and symptoms
141:20 to 40 years old
89:), oriental lily (
77:), morning glory (
6433:
6432:
6424:Allergic rhinitis
6293:
6292:
6188:
6187:
5790:
5789:
5740:
5739:
5697:Empyema/pyothorax
5629:
5628:
5625:
5624:
5583:
5582:
5516:Hospital-acquired
5374:
5373:
5238:Caplan's syndrome
5031:
5030:
4976:Vocal fold nodule
4800:Atrophic rhinitis
4695:
4694:
4691:
4690:
4596:
4595:
4488:
4487:
4397:
4396:
4393:
4392:
4385:Pernicious anemia
4380:Myasthenia gravis
4257:
4256:
4180:Atopic dermatitis
4169:Allergic rhinitis
4084:
4083:
4076:Dust mite allergy
3848:Atopic dermatitis
3784:Allergic rhinitis
3728:Allergic rhinitis
3076:(1 Suppl): S2-8.
2947:10.1111/all.12002
2612:10.1002/alr.21179
2447:10.1111/cea.12148
2441:(10): 1134–1143.
2221:978-1-259-64403-0
2210:Cahill K (2018).
1730:Colgan R (2009).
1637:978-1-259-86290-8
1111:methamphetamine.
750:for the disease.
514:insect-pollinated
294:atopic dermatitis
258:Allergic rhinitis
255:
254:
175:Diagnostic method
168:atopic dermatitis
74:Helianthus annuus
45:Allergic rhinitis
39:Medical condition
16:(Redirected from
6485:
6450:
6449:
6448:
6441:
6297:
6296:
6196:Sympathomimetics
5998:Cromoglicic acid
5885:Levmetamfetamine
5846:Sympathomimetics
5842:
5841:
5817:
5810:
5803:
5794:
5793:
5675:Pleural effusion
5668:Hemopneumothorax
5645:
5644:
5399:
5398:
5385:
5384:
5228:Bauxite fibrosis
5193:External agents/
5190:
5189:
5121:Exercise-induced
5077:Acute bronchitis
5053:
5052:
4753:
4752:
4722:
4715:
4708:
4699:
4698:
4678:Sjögren syndrome
4607:
4606:
4509:
4508:
4414:
4413:
4310:
4309:
4289:
4288:
4149:
4148:
4118:Hypersensitivity
4111:
4104:
4097:
4088:
4087:
4054:Other conditions
3904:Digestive system
3761:
3754:
3747:
3738:
3737:
3725:
3699:
3697:
3695:
3669:
3668:
3632:
3626:
3625:
3615:
3605:
3581:
3575:
3574:
3554:
3548:
3547:
3519:
3513:
3512:
3502:
3470:
3464:
3463:
3461:
3459:
3439:
3433:
3432:
3412:
3406:
3405:
3395:
3363:
3357:
3356:
3346:
3322:
3316:
3315:
3279:
3273:
3272:
3244:
3238:
3237:
3236:
3234:
3211:
3205:
3204:
3186:
3175:
3174:
3164:
3132:
3126:
3125:
3123:
3121:
3102:
3096:
3095:
3085:
3061:
3055:
3042:
3036:
3035:
3033:
3031:
3012:
3006:
3005:
3003:
3001:
2973:
2967:
2966:
2930:
2924:
2923:
2905:
2881:
2875:
2874:
2872:
2870:
2855:
2849:
2848:
2846:
2844:
2812:
2799:
2798:
2762:
2753:
2752:
2741:
2735:
2734:
2732:
2730:
2715:
2702:
2701:
2689:
2683:
2682:
2672:
2662:
2638:
2632:
2631:
2594:
2588:
2587:
2579:
2573:
2572:
2562:
2522:
2516:
2515:
2505:
2473:
2467:
2466:
2435:Clin Exp Allergy
2429:
2423:
2422:
2386:
2377:
2376:
2345:Clin Exp Allergy
2340:
2334:
2333:
2331:
2329:
2311:
2305:
2304:
2302:
2300:
2283:
2277:
2276:
2258:
2252:
2251:
2249:
2247:
2232:
2226:
2225:
2207:
2196:
2195:
2190:
2165:
2159:
2158:
2148:
2124:
2118:
2117:
2097:
2091:
2090:
2071:Pray WS (2005).
2068:
2062:
2061:
2051:
2011:
2005:
2004:
1994:
1969:(3): e135–e138.
1954:
1948:
1947:
1927:
1921:
1920:
1918:
1916:
1884:
1865:
1864:
1841:
1832:
1831:
1825:
1823:
1791:
1782:
1781:
1779:
1777:
1761:
1752:
1751:
1727:
1718:
1717:
1715:
1713:
1685:
1672:
1671:
1669:
1667:
1656:Cleveland Clinic
1648:
1642:
1641:
1623:
1614:
1613:
1585:
1576:
1575:
1573:
1571:
1566:on June 17, 2015
1552:
1537:
1536:
1534:
1532:
1527:on June 17, 2015
1513:
1504:
1503:
1501:
1499:
1494:on June 17, 2015
1480:
1469:
1468:
1466:
1464:
1459:on June 17, 2015
1445:
1424:
1423:
1413:
1381:
1348:
1347:
1345:
1343:
1338:on June 18, 2015
1324:
1287:. The link with
1281:Charles Blackley
1232:house dust mites
1187:nasal irrigation
1042:nasal irrigation
833:, also known as
669:Grasses (Family
660:, and flowering
586:), linden/lime (
462:cross-reactivity
440:nasal turbinates
436:allergic shiners
390:. The link with
384:Charles Blackley
380:Abu Bakr al-Razi
104:Ricinus communis
80:Ipomoea purpurea
62:
42:
41:
21:
6493:
6492:
6488:
6487:
6486:
6484:
6483:
6482:
6458:
6457:
6456:
6446:
6444:
6436:
6434:
6429:
6428:
6376:
6375:
6308:
6294:
6289:
6288:
6273:Clinical trials
6252:
6219:Pseudoephedrine
6194:
6184:
6168:
6102:
6029:Corticosteroids
6023:
5953:
5944:
5915:Propylhexedrine
5890:Methylephedrine
5831:
5821:
5791:
5786:
5736:
5713:
5649:Pleural disease
5638:
5621:
5579:
5541:
5525:By distribution
5520:
5499:By vector/route
5494:
5392:
5380:
5370:
5325:Pulmonary edema
5303:
5198:
5194:
5181:
5177:
5168:
5133:Cystic fibrosis
5060:
5044:
5040:
5027:
4871:
4745:
4739:
4731:
4726:
4696:
4687:
4639:
4602:
4592:
4574:
4570:Type 1 diabetes
4540:Coeliac disease
4528:
4500:
4484:
4458:
4424:Arthus reaction
4405:
4389:
4375:Graves' disease
4356:
4352:Rheumatic fever
4301:
4269:
4253:
4232:
4159:Allergic asthma
4140:
4124:
4115:
4085:
4080:
4049:
4031:
4013:
3912:Coeliac disease
3898:
3880:
3862:
3824:
3770:
3765:
3710:
3707:
3702:
3693:
3691:
3682:
3678:
3676:Further reading
3673:
3672:
3633:
3629:
3582:
3578:
3555:
3551:
3520:
3516:
3485:(1): CD001936.
3471:
3467:
3457:
3455:
3440:
3436:
3413:
3409:
3378:(6): CD012597.
3364:
3360:
3323:
3319:
3280:
3276:
3245:
3241:
3232:
3230:
3212:
3208:
3201:
3187:
3178:
3147:(7): CD006989.
3133:
3129:
3119:
3117:
3110:MedlinePlus.gov
3104:
3103:
3099:
3062:
3058:
3053:Wayback Machine
3043:
3039:
3029:
3027:
3014:
3013:
3009:
2999:
2997:
2990:
2974:
2970:
2931:
2927:
2882:
2878:
2868:
2866:
2857:
2856:
2852:
2842:
2840:
2813:
2802:
2763:
2756:
2745:"Allergy Tests"
2743:
2742:
2738:
2728:
2726:
2717:
2716:
2705:
2690:
2686:
2639:
2635:
2595:
2591:
2580:
2576:
2523:
2519:
2474:
2470:
2430:
2426:
2387:
2380:
2341:
2337:
2327:
2325:
2312:
2308:
2298:
2296:
2285:
2284:
2280:
2273:
2259:
2255:
2245:
2243:
2234:
2233:
2229:
2222:
2208:
2199:
2188:
2166:
2162:
2135:(in Japanese).
2125:
2121:
2098:
2094:
2087:
2079:. p. 221.
2069:
2065:
2012:
2008:
1955:
1951:
1928:
1924:
1914:
1912:
1885:
1868:
1857:
1843:
1842:
1835:
1821:
1819:
1792:
1785:
1775:
1773:
1762:
1755:
1744:
1728:
1721:
1711:
1709:
1702:
1686:
1675:
1665:
1663:
1650:
1649:
1645:
1638:
1624:
1617:
1586:
1579:
1569:
1567:
1554:
1553:
1540:
1530:
1528:
1515:
1514:
1507:
1497:
1495:
1482:
1481:
1472:
1462:
1460:
1447:
1446:
1427:
1382:
1351:
1341:
1339:
1326:
1325:
1318:
1313:
1301:
1273:
1261:
1240:
1228:
1204:corticosteroids
1171:
1138:nasal spray to
1121:
1108:Pseudoephedrine
1090:diphenhydramine
1054:
1022:corticosteroids
1018:
1002:
952:
935:atopic rhinitis
913:
882:RAST blood test
863:
814:phosphorylation
740:
738:Genetic factors
682:Phleum pratense
647:double-flowered
622:) tree pollen.
499:wind-pollinated
486:
471:
451:allergic salute
404:
356:cromolyn sodium
352:diphenhydramine
325:skin prick test
264:, is a type of
230:cromolyn sodium
226:diphenhydramine
181:skin prick test
40:
35:
28:
23:
22:
15:
12:
11:
5:
6491:
6481:
6480:
6475:
6470:
6455:
6454:
6431:
6430:
6427:
6426:
6415:
6397:
6385:
6384:
6382:
6378:
6377:
6374:
6373:
6362:
6351:
6340:
6325:
6309:
6304:
6303:
6301:
6300:Classification
6291:
6290:
6287:
6286:
6285:
6284:
6281:
6270:
6264:
6258:
6257:
6254:
6253:
6251:
6250:
6227:+carbinoxamine
6216:
6211:
6206:
6200:
6198:
6190:
6189:
6186:
6185:
6183:
6182:
6176:
6174:
6170:
6169:
6167:
6166:
6161:
6156:
6151:
6146:
6141:
6136:
6131:
6126:
6124:Eucalyptus oil
6121:
6116:
6110:
6108:
6104:
6103:
6101:
6100:
6095:
6090:
6085:
6080:
6075:
6064:
6059:
6054:
6049:
6044:
6039:
6033:
6031:
6025:
6024:
6022:
6021:
6015:
6010:
6005:
6000:
5988:
5987:
5981:
5976:
5964:
5963:
5961:Spaglumic acid
5957:
5955:
5946:
5945:
5943:
5942:
5940:Xylometazoline
5937:
5932:
5930:Tuaminoheptane
5927:
5922:
5917:
5912:
5907:
5902:
5897:
5892:
5887:
5882:
5877:
5872:
5867:
5862:
5860:Cyclopentamine
5857:
5851:
5849:
5839:
5833:
5832:
5820:
5819:
5812:
5805:
5797:
5788:
5787:
5785:
5784:
5779:
5774:
5769:
5764:
5759:
5754:
5748:
5746:
5742:
5741:
5738:
5737:
5735:
5734:
5729:
5723:
5721:
5715:
5714:
5712:
5711:
5705:
5704:
5699:
5694:
5689:
5684:
5679:
5677:
5671:
5670:
5660:
5659:
5653:
5651:
5642:
5635:Pleural cavity
5631:
5630:
5627:
5626:
5623:
5622:
5620:
5619:
5614:
5613:
5612:
5607:
5597:
5591:
5589:
5585:
5584:
5581:
5580:
5578:
5577:
5572:
5567:
5562:
5557:
5551:
5549:
5543:
5542:
5540:
5539:
5534:
5528:
5526:
5522:
5521:
5519:
5518:
5513:
5508:
5502:
5500:
5496:
5495:
5493:
5492:
5491:
5490:
5481:
5467:
5462:
5461:
5460:
5450:
5449:
5448:
5443:
5438:
5428:
5427:
5426:
5421:
5411:
5405:
5403:
5396:
5382:
5376:
5375:
5372:
5371:
5369:
5368:
5363:
5358:
5353:
5348:
5347:
5346:
5336:
5327:
5322:
5317:
5311:
5309:
5305:
5304:
5302:
5301:
5300:
5299:
5297:Lycoperdonosis
5294:
5289:
5284:
5273:
5272:
5271:
5270:
5265:
5260:
5255:
5250:
5245:
5240:
5235:
5230:
5225:
5220:
5215:
5208:Pneumoconiosis
5204:
5202:
5187:
5170:
5169:
5167:
5166:
5161:
5160:
5159:
5149:
5144:
5142:
5136:
5135:
5130:
5128:Bronchiectasis
5125:
5124:
5123:
5118:
5113:
5104:
5098:
5088:
5086:
5080:
5079:
5074:
5072:
5066:
5064:
5050:
5033:
5032:
5029:
5028:
5026:
5025:
5020:
5015:
5013:
5005:
5004:
4999:
4997:
4989:
4988:
4983:
4978:
4973:
4967:
4965:
4957:
4956:
4951:
4945:
4940:
4938:Laryngeal cyst
4935:
4933:Laryngomalacia
4930:
4925:
4923:
4915:
4914:
4909:
4903:
4902:
4901:
4891:
4889:
4881:
4879:
4873:
4872:
4870:
4869:
4864:
4859:
4854:
4852:
4844:
4843:
4842:
4841:
4836:
4831:
4819:
4814:
4809:
4808:
4807:
4802:
4797:
4787:
4785:
4777:
4776:
4771:
4769:
4761:
4759:
4750:
4733:
4732:
4725:
4724:
4717:
4710:
4702:
4693:
4692:
4689:
4688:
4686:
4685:
4680:
4675:
4674:
4673:
4668:
4658:
4653:
4647:
4645:
4641:
4640:
4638:
4637:
4632:
4626:
4625:
4624:
4613:
4611:
4604:
4598:
4597:
4594:
4593:
4591:
4590:
4584:
4582:
4576:
4575:
4573:
4572:
4567:
4562:
4557:
4552:
4547:
4542:
4536:
4534:
4530:
4529:
4527:
4526:
4521:
4515:
4513:
4506:
4490:
4489:
4486:
4485:
4483:
4482:
4477:
4472:
4466:
4464:
4460:
4459:
4457:
4456:
4454:Serum sickness
4451:
4446:
4441:
4436:
4431:
4426:
4420:
4418:
4411:
4408:Immune complex
4399:
4398:
4395:
4394:
4391:
4390:
4388:
4387:
4382:
4377:
4371:
4369:
4358:
4357:
4355:
4354:
4349:
4344:
4339:
4334:
4329:
4324:
4318:
4316:
4307:
4303:
4302:
4300:
4295:
4293:
4286:
4285:
4284:
4283:
4282:
4277:
4259:
4258:
4255:
4254:
4252:
4251:
4246:
4240:
4238:
4234:
4233:
4231:
4230:
4225:
4224:
4223:
4218:
4213:
4208:
4203:
4198:
4193:
4182:
4177:
4172:
4166:
4161:
4155:
4153:
4146:
4126:
4125:
4114:
4113:
4106:
4099:
4091:
4082:
4081:
4079:
4078:
4073:
4068:
4063:
4057:
4055:
4051:
4050:
4048:
4047:
4041:
4039:
4033:
4032:
4030:
4029:
4023:
4021:
4019:Nervous system
4015:
4014:
4012:
4011:
4010:
4009:
4004:
3999:
3994:
3989:
3984:
3979:
3974:
3969:
3968:
3967:
3962:
3954:
3949:
3944:
3939:
3934:
3924:
3919:
3914:
3908:
3906:
3900:
3899:
3897:
3896:
3890:
3888:
3882:
3881:
3879:
3878:
3876:Serum sickness
3872:
3870:
3864:
3863:
3861:
3860:
3855:
3850:
3845:
3840:
3834:
3832:
3826:
3825:
3823:
3822:
3817:
3812:
3807:
3802:
3797:
3792:
3787:
3780:
3778:
3772:
3771:
3764:
3763:
3756:
3749:
3741:
3735:
3734:
3706:
3705:External links
3703:
3701:
3700:
3679:
3677:
3674:
3671:
3670:
3627:
3576:
3549:
3530:(5): 1054–62.
3514:
3465:
3434:
3423:(8): 713–720.
3407:
3358:
3317:
3274:
3239:
3216:"Fexofenadine"
3206:
3200:978-0071478991
3199:
3176:
3127:
3097:
3056:
3037:
3007:
2988:
2968:
2941:(10): 1282–8.
2925:
2876:
2850:
2800:
2754:
2736:
2703:
2684:
2633:
2606:(8): 612–620.
2589:
2574:
2517:
2468:
2424:
2378:
2351:(2): 218–228.
2335:
2306:
2278:
2271:
2253:
2227:
2220:
2197:
2160:
2119:
2108:(30): 338–40.
2092:
2086:978-0781734981
2085:
2063:
2026:(3): 220–221.
2006:
1949:
1922:
1899:(11): 985–92.
1866:
1855:
1833:
1783:
1753:
1742:
1719:
1700:
1673:
1643:
1636:
1615:
1577:
1538:
1505:
1470:
1425:
1349:
1315:
1314:
1312:
1309:
1308:
1307:
1300:
1297:
1272:
1269:
1260:
1257:
1239:
1236:
1227:
1224:
1170:
1167:
1159:glucocorticoid
1120:
1117:
1053:
1052:Antihistamines
1050:
1026:antihistamines
1017:
1014:
1001:
998:
980:conjunctivitis
951:
948:
939:
938:
924:
912:
911:Classification
909:
862:
859:
831:protein family
827:Immunoglobulin
760:interleukin-33
758:(SNPs) in the
739:
736:
732:Balsam of Peru
728:
727:
686:
667:
666:
665:
592:), and olive (
485:
482:
470:
467:
403:
400:
348:antihistamines
309:IgE antibodies
272:overreacts to
253:
252:
249:
245:
244:
222:antihistamines
214:
208:
207:
204:
200:
199:
194:
188:
187:
177:
171:
170:
157:
151:
150:
147:
143:
142:
139:
135:
134:
127:
121:
120:
115:
109:
108:
92:Lilium auratum
64:
63:
55:
54:
51:
47:
46:
38:
26:
9:
6:
4:
3:
2:
6490:
6479:
6476:
6474:
6471:
6469:
6466:
6465:
6463:
6453:
6443:
6442:
6439:
6425:
6421:
6420:
6416:
6414:
6410:
6407:
6403:
6402:
6398:
6396:
6392:
6391:
6387:
6386:
6383:
6379:
6372:
6368:
6367:
6363:
6361:
6357:
6356:
6352:
6350:
6346:
6345:
6341:
6339:
6335:
6334:
6330:
6326:
6324:
6320:
6319:
6315:
6311:
6310:
6307:
6302:
6298:
6282:
6280:
6277:
6276:
6274:
6271:
6268:
6265:
6263:
6260:
6259:
6255:
6248:
6244:
6240:
6239:+fexofenadine
6236:
6232:
6228:
6224:
6220:
6217:
6215:
6212:
6210:
6209:Phenylephrine
6207:
6205:
6202:
6201:
6199:
6197:
6193:Systemic use:
6191:
6181:
6178:
6177:
6175:
6171:
6165:
6162:
6160:
6157:
6155:
6152:
6150:
6147:
6145:
6142:
6140:
6137:
6135:
6132:
6130:
6127:
6125:
6122:
6120:
6117:
6115:
6112:
6111:
6109:
6105:
6099:
6096:
6094:
6093:Triamcinolone
6091:
6089:
6086:
6084:
6081:
6079:
6076:
6073:
6069:
6066:Fluticasone (
6065:
6063:
6060:
6058:
6057:Dexamethasone
6055:
6053:
6050:
6048:
6045:
6043:
6042:Betamethasone
6040:
6038:
6035:
6034:
6032:
6030:
6026:
6019:
6016:
6014:
6011:
6009:
6006:
6004:
6001:
5999:
5995:
5994:
5990:
5989:
5985:
5982:
5980:
5977:
5975:
5974:Levocabastine
5971:
5970:
5966:
5965:
5962:
5959:
5958:
5956:
5951:
5947:
5941:
5938:
5936:
5933:
5931:
5928:
5926:
5923:
5921:
5918:
5916:
5913:
5911:
5910:Phenylephrine
5908:
5906:
5905:Oxymetazoline
5903:
5901:
5898:
5896:
5893:
5891:
5888:
5886:
5883:
5881:
5878:
5876:
5873:
5871:
5868:
5866:
5863:
5861:
5858:
5856:
5853:
5852:
5850:
5847:
5843:
5840:
5838:
5834:
5829:
5825:
5824:Decongestants
5818:
5813:
5811:
5806:
5804:
5799:
5798:
5795:
5783:
5780:
5778:
5775:
5773:
5770:
5768:
5765:
5763:
5760:
5758:
5755:
5753:
5750:
5749:
5747:
5745:Other/general
5743:
5733:
5730:
5728:
5727:Mediastinitis
5725:
5724:
5722:
5720:
5716:
5710:
5707:
5706:
5703:
5700:
5698:
5695:
5693:
5690:
5688:
5685:
5683:
5680:
5678:
5676:
5673:
5672:
5669:
5665:
5662:
5661:
5658:
5655:
5654:
5652:
5650:
5646:
5643:
5641:
5636:
5632:
5618:
5615:
5611:
5608:
5606:
5603:
5602:
5601:
5598:
5596:
5593:
5592:
5590:
5586:
5576:
5573:
5571:
5568:
5566:
5563:
5561:
5558:
5556:
5553:
5552:
5550:
5548:
5544:
5538:
5535:
5533:
5530:
5529:
5527:
5523:
5517:
5514:
5512:
5509:
5507:
5504:
5503:
5501:
5497:
5489:
5485:
5482:
5480:
5476:
5473:
5472:
5471:
5470:noninfectious
5468:
5466:
5463:
5459:
5456:
5455:
5454:
5451:
5447:
5444:
5442:
5439:
5437:
5434:
5433:
5432:
5429:
5425:
5422:
5420:
5417:
5416:
5415:
5412:
5410:
5407:
5406:
5404:
5400:
5397:
5395:
5390:
5386:
5383:
5379:Obstructive /
5377:
5367:
5364:
5362:
5359:
5357:
5354:
5352:
5349:
5345:
5342:
5341:
5340:
5337:
5335:
5331:
5328:
5326:
5323:
5321:
5318:
5316:
5313:
5312:
5310:
5306:
5298:
5295:
5293:
5292:Farmer's lung
5290:
5288:
5285:
5283:
5280:
5279:
5278:
5275:
5274:
5269:
5266:
5264:
5261:
5259:
5256:
5254:
5251:
5249:
5246:
5244:
5241:
5239:
5236:
5234:
5231:
5229:
5226:
5224:
5221:
5219:
5216:
5214:
5211:
5210:
5209:
5206:
5205:
5203:
5201:
5197:
5191:
5188:
5185:
5180:
5175:
5171:
5165:
5162:
5158:
5155:
5154:
5153:
5152:Bronchiolitis
5150:
5148:
5145:
5143:
5141:
5138:
5137:
5134:
5131:
5129:
5126:
5122:
5119:
5117:
5114:
5112:
5108:
5105:
5102:
5099:
5097:
5094:
5093:
5092:
5089:
5087:
5085:
5082:
5081:
5078:
5075:
5073:
5071:
5068:
5067:
5065:
5063:
5058:
5054:
5051:
5048:
5043:
5038:
5034:
5024:
5021:
5019:
5016:
5014:
5012:
5011:
5007:
5006:
5003:
5000:
4998:
4996:
4995:
4991:
4990:
4987:
4984:
4982:
4979:
4977:
4974:
4971:
4968:
4966:
4964:
4963:
4959:
4958:
4955:
4952:
4949:
4946:
4944:
4941:
4939:
4936:
4934:
4931:
4929:
4926:
4924:
4922:
4921:
4917:
4916:
4913:
4910:
4907:
4904:
4900:
4897:
4896:
4895:
4892:
4890:
4888:
4887:
4883:
4882:
4880:
4878:
4874:
4868:
4865:
4863:
4860:
4858:
4855:
4853:
4851:
4850:
4846:
4845:
4840:
4837:
4835:
4832:
4830:
4827:
4826:
4825:
4824:
4820:
4818:
4815:
4813:
4810:
4806:
4803:
4801:
4798:
4796:
4793:
4792:
4791:
4788:
4786:
4784:
4783:
4779:
4778:
4775:
4772:
4770:
4768:
4767:
4763:
4762:
4760:
4758:
4754:
4751:
4748:
4743:
4738:
4734:
4730:
4723:
4718:
4716:
4711:
4709:
4704:
4703:
4700:
4684:
4681:
4679:
4676:
4672:
4669:
4667:
4664:
4663:
4662:
4659:
4657:
4654:
4652:
4649:
4648:
4646:
4642:
4636:
4633:
4630:
4629:Latex allergy
4627:
4623:
4620:
4619:
4618:
4615:
4614:
4612:
4608:
4605:
4599:
4589:
4586:
4585:
4583:
4581:
4577:
4571:
4568:
4566:
4563:
4561:
4558:
4556:
4553:
4551:
4548:
4546:
4543:
4541:
4538:
4537:
4535:
4531:
4525:
4522:
4520:
4517:
4516:
4514:
4510:
4507:
4504:
4499:
4498:cell-mediated
4495:
4491:
4481:
4478:
4476:
4473:
4471:
4468:
4467:
4465:
4461:
4455:
4452:
4450:
4447:
4445:
4442:
4440:
4437:
4435:
4432:
4430:
4429:Farmer's lung
4427:
4425:
4422:
4421:
4419:
4415:
4412:
4409:
4404:
4400:
4386:
4383:
4381:
4378:
4376:
4373:
4372:
4370:
4368:
4364:
4359:
4353:
4350:
4348:
4345:
4343:
4340:
4338:
4335:
4333:
4330:
4328:
4325:
4323:
4320:
4319:
4317:
4315:
4311:
4308:
4304:
4299:
4296:
4294:
4290:
4287:
4281:
4278:
4276:
4273:
4272:
4271:
4270:
4268:
4264:
4260:
4250:
4247:
4245:
4242:
4241:
4239:
4235:
4229:
4226:
4222:
4219:
4217:
4214:
4212:
4209:
4207:
4204:
4202:
4199:
4197:
4194:
4192:
4188:
4187:
4186:
4183:
4181:
4178:
4176:
4173:
4170:
4167:
4165:
4162:
4160:
4157:
4156:
4154:
4150:
4147:
4144:
4139:
4135:
4131:
4127:
4123:
4119:
4112:
4107:
4105:
4100:
4098:
4093:
4092:
4089:
4077:
4074:
4072:
4071:Latex allergy
4069:
4067:
4064:
4062:
4059:
4058:
4056:
4052:
4046:
4043:
4042:
4040:
4038:
4034:
4028:
4025:
4024:
4022:
4020:
4016:
4008:
4005:
4003:
4000:
3998:
3995:
3993:
3990:
3988:
3985:
3983:
3980:
3978:
3975:
3973:
3970:
3966:
3963:
3961:
3958:
3957:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3929:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3909:
3907:
3905:
3901:
3895:
3892:
3891:
3889:
3887:
3883:
3877:
3874:
3873:
3871:
3869:
3865:
3859:
3856:
3854:
3851:
3849:
3846:
3844:
3841:
3839:
3836:
3835:
3833:
3831:
3827:
3821:
3818:
3816:
3815:Farmer's lung
3813:
3811:
3808:
3806:
3803:
3801:
3798:
3796:
3793:
3791:
3788:
3785:
3782:
3781:
3779:
3777:
3773:
3769:
3762:
3757:
3755:
3750:
3748:
3743:
3742:
3739:
3733:
3729:
3723:
3719:
3718:
3714:
3709:
3708:
3689:
3685:
3681:
3680:
3666:
3662:
3658:
3654:
3650:
3646:
3643:(1–2): 42–5.
3642:
3638:
3631:
3623:
3619:
3614:
3609:
3604:
3599:
3595:
3591:
3587:
3580:
3572:
3568:
3564:
3560:
3553:
3545:
3541:
3537:
3533:
3529:
3525:
3518:
3510:
3506:
3501:
3496:
3492:
3488:
3484:
3480:
3476:
3469:
3453:
3449:
3445:
3438:
3430:
3426:
3422:
3418:
3411:
3403:
3399:
3394:
3389:
3385:
3381:
3377:
3373:
3369:
3362:
3354:
3350:
3345:
3340:
3337:(4): 927–34.
3336:
3332:
3328:
3321:
3313:
3309:
3305:
3301:
3297:
3293:
3289:
3285:
3278:
3270:
3266:
3262:
3258:
3255:(3): 277–81.
3254:
3250:
3243:
3229:
3225:
3221:
3217:
3210:
3202:
3196:
3192:
3185:
3183:
3181:
3172:
3168:
3163:
3158:
3154:
3150:
3146:
3142:
3138:
3131:
3115:
3111:
3107:
3101:
3093:
3089:
3084:
3079:
3075:
3071:
3067:
3060:
3054:
3050:
3047:
3041:
3025:
3021:
3017:
3011:
2995:
2991:
2989:9780323278201
2985:
2981:
2980:
2972:
2964:
2960:
2956:
2952:
2948:
2944:
2940:
2936:
2929:
2921:
2917:
2913:
2909:
2904:
2899:
2895:
2891:
2887:
2880:
2864:
2860:
2854:
2838:
2834:
2830:
2826:
2822:
2818:
2811:
2809:
2807:
2805:
2796:
2792:
2788:
2784:
2780:
2776:
2772:
2768:
2761:
2759:
2750:
2746:
2740:
2724:
2720:
2714:
2712:
2710:
2708:
2700:(3): 901–912.
2699:
2695:
2688:
2680:
2676:
2671:
2666:
2661:
2656:
2652:
2648:
2647:Front Immunol
2644:
2637:
2629:
2625:
2621:
2617:
2613:
2609:
2605:
2601:
2593:
2585:
2578:
2570:
2566:
2561:
2556:
2552:
2548:
2544:
2540:
2536:
2532:
2528:
2521:
2513:
2509:
2504:
2499:
2495:
2491:
2487:
2483:
2479:
2472:
2464:
2460:
2456:
2452:
2448:
2444:
2440:
2436:
2428:
2420:
2416:
2412:
2408:
2404:
2400:
2396:
2392:
2385:
2383:
2374:
2370:
2366:
2362:
2358:
2354:
2350:
2346:
2339:
2323:
2319:
2318:
2310:
2294:
2290:
2289:
2282:
2274:
2272:9781472103949
2268:
2264:
2257:
2241:
2237:
2231:
2223:
2217:
2213:
2206:
2204:
2202:
2193:
2187:
2183:
2179:
2175:
2172:(in French).
2171:
2164:
2156:
2152:
2147:
2142:
2139:(10): 971–9.
2138:
2134:
2130:
2123:
2115:
2111:
2107:
2104:(in Polish).
2103:
2096:
2088:
2082:
2078:
2074:
2067:
2059:
2055:
2050:
2045:
2041:
2037:
2033:
2029:
2025:
2021:
2017:
2010:
2002:
1998:
1993:
1988:
1984:
1980:
1976:
1972:
1968:
1964:
1960:
1953:
1945:
1941:
1937:
1933:
1926:
1910:
1906:
1902:
1898:
1894:
1890:
1883:
1881:
1879:
1877:
1875:
1873:
1871:
1862:
1858:
1856:9783318021950
1852:
1848:
1847:
1840:
1838:
1830:
1822:September 23,
1817:
1813:
1809:
1805:
1801:
1797:
1790:
1788:
1771:
1767:
1760:
1758:
1749:
1745:
1743:9781441910349
1739:
1735:
1734:
1726:
1724:
1712:September 23,
1707:
1703:
1701:9789997619846
1697:
1693:
1692:
1684:
1682:
1680:
1678:
1661:
1657:
1653:
1647:
1639:
1633:
1629:
1622:
1620:
1611:
1607:
1603:
1599:
1595:
1591:
1584:
1582:
1565:
1561:
1557:
1551:
1549:
1547:
1545:
1543:
1526:
1522:
1518:
1512:
1510:
1493:
1489:
1485:
1479:
1477:
1475:
1458:
1454:
1450:
1444:
1442:
1440:
1438:
1436:
1434:
1432:
1430:
1421:
1417:
1412:
1407:
1403:
1399:
1396:(5): 456–63.
1395:
1391:
1387:
1380:
1378:
1376:
1374:
1372:
1370:
1368:
1366:
1364:
1362:
1360:
1358:
1356:
1354:
1337:
1333:
1329:
1323:
1321:
1316:
1306:
1303:
1302:
1296:
1294:
1290:
1286:
1282:
1278:
1268:
1266:
1256:
1254:
1249:
1245:
1235:
1233:
1223:
1219:
1217:
1213:
1209:
1208:oxymetazoline
1205:
1200:
1198:
1194:
1190:
1188:
1184:
1180:
1176:
1175:decongestants
1166:
1164:
1163:betamethasone
1160:
1156:
1152:
1148:
1143:
1141:
1140:betamethasone
1137:
1132:
1129:
1125:
1116:
1114:
1109:
1105:
1103:
1099:
1095:
1091:
1087:
1083:
1078:
1076:
1072:
1067:
1065:
1060:
1058:
1057:Antihistamine
1049:
1047:
1043:
1039:
1035:
1031:
1030:decongestants
1027:
1023:
1013:
1009:
1006:
997:
994:
992:
987:
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867:
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819:
818:proliferation
815:
811:
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799:
794:
791:
790:polymorphisms
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782:
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753:
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724:
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713:
709:
705:
701:
700:
696:), plantain (
695:
691:
687:
684:
683:
678:
677:
672:
668:
663:
659:
655:
651:
648:
644:
640:
636:
635:yellow poplar
632:
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617:
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579:
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567:
566:
561:
560:
556:), hornbeam (
555:
554:
549:
548:
543:
542:
537:
536:
531:
530:
526:), mulberry (
525:
524:
519:
518:
517:
515:
512:. Pollens of
511:
507:
503:
500:
495:
491:
481:
479:
474:
466:
463:
458:
456:
452:
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443:
441:
437:
433:
429:
426:swelling and
425:
421:
417:
408:
399:
397:
393:
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385:
381:
376:
371:
369:
365:
361:
357:
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349:
345:
341:
336:
334:
330:
326:
322:
318:
314:
310:
306:
302:
297:
295:
291:
287:
283:
279:
275:
271:
270:immune system
267:
263:
259:
250:
246:
243:
239:
235:
231:
227:
223:
219:
215:
213:
209:
205:
201:
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182:
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172:
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148:
144:
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136:
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126:
122:
119:
116:
114:
110:
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100:
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6417:
6399:
6388:
6364:
6353:
6342:
6327:
6312:
6164:Saline water
6083:Prednisolone
5991:
5984:Thonzylamine
5967:
5950:Antiallergic
5875:Fenoxazoline
5664:Pneumothorax
5617:Lung abscess
5599:
5469:
5458:Pneumocystis
5419:Pneumococcal
5200:lung disease
5196:occupational
5174:Interstitial
5139:
5083:
5069:
5042:lung disease
5008:
5002:Epiglottitis
4992:
4960:
4954:Laryngospasm
4918:
4899:Strep throat
4884:
4847:
4823:nasal septum
4821:
4804:
4780:
4764:
4524:Mantoux test
4185:Food allergy
4168:
4061:Drug allergy
3927:Food allergy
3783:
3715:
3692:. Retrieved
3640:
3636:
3630:
3593:
3589:
3579:
3562:
3558:
3552:
3527:
3523:
3517:
3482:
3478:
3468:
3456:. Retrieved
3447:
3442:Creticos P.
3437:
3420:
3416:
3410:
3375:
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3361:
3334:
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3287:
3283:
3277:
3252:
3248:
3242:
3231:, retrieved
3219:
3209:
3190:
3144:
3140:
3130:
3118:. Retrieved
3109:
3100:
3073:
3069:
3059:
3040:
3030:February 17,
3028:. Retrieved
3019:
3016:"Prevention"
3010:
2998:. Retrieved
2978:
2971:
2938:
2934:
2928:
2896:(8): 990–6.
2893:
2889:
2879:
2867:. Retrieved
2853:
2843:December 27,
2841:. Retrieved
2824:
2820:
2770:
2766:
2739:
2729:November 25,
2727:. Retrieved
2697:
2693:
2687:
2650:
2646:
2636:
2603:
2599:
2592:
2583:
2577:
2534:
2530:
2520:
2485:
2482:Exp Ther Med
2481:
2471:
2438:
2434:
2427:
2394:
2390:
2348:
2344:
2338:
2326:. Retrieved
2316:
2309:
2297:. Retrieved
2287:
2281:
2262:
2256:
2244:. Retrieved
2230:
2211:
2176:(7): 253–6.
2173:
2169:
2163:
2136:
2132:
2122:
2105:
2101:
2095:
2072:
2066:
2023:
2019:
2009:
1966:
1962:
1952:
1939:
1935:
1925:
1913:. Retrieved
1896:
1892:
1845:
1827:
1820:. Retrieved
1806:(768): 245.
1803:
1799:
1774:. Retrieved
1732:
1710:. Retrieved
1690:
1664:. Retrieved
1655:
1646:
1627:
1593:
1589:
1568:. Retrieved
1564:the original
1559:
1529:. Retrieved
1525:the original
1520:
1496:. Retrieved
1492:the original
1487:
1461:. Retrieved
1457:the original
1452:
1393:
1389:
1340:. Retrieved
1336:the original
1331:
1274:
1262:
1259:Epidemiology
1241:
1229:
1220:
1201:
1191:
1172:
1144:
1133:
1128:nasal sprays
1122:
1106:
1098:fexofenadine
1079:
1068:
1061:
1055:
1019:
1010:
1007:
1003:
995:
988:
976:
953:
944:
940:
934:
930:
926:
920:
916:
894:
890:
886:eosinophilia
874:
839:
823:glycoprotein
795:
741:
729:
721:
715:
714:), Fat hen (
711:
697:
693:
680:
674:
619:
611:
593:
587:
581:
575:
569:
563:
557:
551:
545:
539:
533:
527:
521:
487:
478:atopic triad
475:
472:
459:
447:nasal salute
446:
444:
438:"), swollen
424:conjunctival
413:
372:
337:
303:. Inherited
298:
261:
257:
256:
155:Risk factors
102:
96:
90:
84:
78:
72:
36:
6468:Allergology
6390:MedlinePlus
6269:from market
6243:+loratadine
6231:+cetirizine
6062:Flunisolide
6052:Ciclesonide
6013:Olopatadine
5925:Tramazoline
5920:Tetryzoline
5900:Naphazoline
5880:Iproheptine
5870:Epinephrine
5855:Amidephrine
5762:Common cold
5709:Fibrothorax
5692:Chylothorax
5687:Hydrothorax
5640:mediastinum
5600:circulatory
5595:Atelectasis
5402:By pathogen
5394:pneumonitis
5381:Restrictive
5361:Sarcoidosis
5233:Berylliosis
5179:restrictive
5140:unspecified
5062:obstructive
5045:(including
4962:vocal cords
4894:Pharyngitis
4857:Tonsillitis
4812:Nasal polyp
4747:common cold
4740:(including
4175:Anaphylaxis
4171:(Hay fever)
3894:Anaphylaxis
3786:(hay fever)
3596:: 6478102.
3458:December 2,
3290:(1): 63–9.
1293:correlation
1244:acupuncture
960:blood tests
901:blood tests
717:Chenopodium
574:), poplar (
568:), willow (
510:Aerobiology
506:bioaerosols
396:correlation
382:. In 1859,
364:montelukast
340:medications
329:common cold
238:montelukast
197:Common cold
138:Usual onset
50:Other names
6462:Categories
6419:Patient UK
6366:DiseasesDB
6223:+azatadine
6159:Ritiometan
6139:Hyaluronan
6134:Hexamidine
6129:Framycetin
6088:Tixocortol
6047:Budesonide
6018:Lodoxamide
6008:Azelastine
6003:Nedocromil
5979:Antazoline
5935:Tymazoline
5895:Metizoline
5682:Hemothorax
5484:Aspiration
5446:Chlamydiae
5436:Mycoplasma
5424:Klebsiella
5282:Bagassosis
5268:Byssinosis
5243:Chalicosis
5218:Asbestosis
5213:Aluminosis
5147:Bronchitis
5018:Tracheitis
4994:epiglottis
4943:Laryngitis
4817:Rhinorrhea
4644:Autoimmune
4533:Autoimmune
4463:Autoimmune
4306:Autoimmune
4237:Autoimmune
3838:Angioedema
3565:: 703–10.
3233:August 16,
3220:StatPearls
2773:(1): 1–7.
2586:: 413–419.
2537:(5): 102.
2488:(5): 102.
2397:(2): 415.
1936:Consultant
1800:The Lancet
1311:References
1305:Hemp fever
1248:homeopathy
1151:prednisone
1124:Intranasal
1102:loratadine
1082:drowsiness
1000:Prevention
956:skin-prick
942:children.
877:patch test
870:Patch test
842:epigenetic
835:antibodies
785:epithelium
704:Urticaceae
627:female ash
580:), plane (
550:), hazel (
544:), cedar (
538:), alder (
532:), birch (
508:is called
449:" or the "
416:rhinorrhea
350:, such as
317:mast cells
212:Medication
203:Prevention
185:antibodies
6401:eMedicine
6279:Phase III
6267:Withdrawn
6247:+naproxen
6204:Ephedrine
6149:Mupirocin
6114:Cafaminol
5865:Ephedrine
5757:Influenza
5702:Malignant
5465:Parasitic
5414:Bacterial
5389:Pneumonia
5258:Silicosis
5253:Siderosis
5223:Baritosis
5057:Bronchial
4805:Hay fever
4774:Sinusitis
4314:Cytotoxic
4002:tree nuts
3992:shellfish
3843:Urticaria
3720:is being
3694:April 28,
3120:March 18,
3000:April 20,
2551:1792-0981
2328:April 27,
2299:April 27,
2246:April 25,
2040:1308-8734
1983:2152-6575
1942:: 610–3.
1915:April 21,
1666:March 23,
1161:(such as
1145:Systemic
1075:ketotifen
1016:Treatment
921:hay fever
861:Diagnosis
846:microRNAs
840:Finally,
764:cytokines
313:histamine
274:allergens
262:hay fever
248:Frequency
113:Specialty
18:Hay fever
6452:Medicine
6413:ped/2560
5772:COVID-19
5565:BOOP-COP
5532:Broncho-
5475:Chemical
5263:Talcosis
5184:fibrosis
5037:Lower RT
4790:Rhinitis
4737:Upper RT
4603:multiple
4601:Unknown/
4403:Type III
4367:receptor
4216:Tree nut
3965:red meat
3713:template
3688:Archived
3665:31349218
3657:20609633
3622:30992709
3571:15042943
3544:16675332
3509:17253469
3452:Archived
3448:UpToDate
3402:29932206
3353:21377716
3312:24169670
3269:23127728
3228:32310564
3171:20614452
3114:Archived
3092:11449200
3049:Archived
3024:Archived
2994:Archived
2963:22470654
2955:22913574
2920:11933433
2912:18691301
2869:March 5,
2863:Archived
2837:Archived
2833:20945601
2787:20010094
2749:Archived
2723:Archived
2679:28785260
2628:29759402
2620:23704072
2569:32973951
2512:32973951
2463:32689683
2455:24074331
2419:39239208
2411:24408538
2373:21799632
2365:22233535
2322:Archived
2293:Archived
2240:Archived
2192:15195402
2182:14626714
2155:16285612
2114:10101519
2058:29123450
2001:28107144
1944:Archived
1909:Archived
1905:26760413
1861:Archived
1816:Archived
1776:June 19,
1770:Archived
1748:Archived
1706:Archived
1660:Archived
1610:20176255
1570:June 19,
1531:June 17,
1498:June 19,
1463:June 17,
1420:25629743
1342:June 19,
1299:See also
1179:cromolyn
1149:such as
1147:steroids
1119:Steroids
1096:such as
1088:such as
1034:cromolyn
968:allergen
854:exosomes
825:for the
806:lymphoid
699:Plantago
694:Ambrosia
643:magnolia
583:Platanus
565:Aesculus
559:Carpinus
428:erythema
362:such as
344:steroids
321:symptoms
305:genetics
278:sneezing
236:such as
224:such as
218:steroids
131:sneezing
125:Symptoms
6409:med/104
6406:ent/194
6360:D012221
6154:Retinol
5952:agents,
5848:, plain
5837:Topical
5084:chronic
5010:trachea
4886:pharynx
4766:sinuses
4610:Foreign
4512:Foreign
4503:T cells
4494:Type IV
4417:Foreign
4292:Foreign
4263:Type II
4206:Seafood
4152:Foreign
4134:allergy
3977:peanuts
3960:poultry
3613:6434301
3500:7017974
3393:6513421
3304:7358206
3162:7388927
2935:Allergy
2890:Allergy
2795:3472235
2670:5519536
2653:: 826.
2560:7506885
2503:7506885
2049:5665636
1992:5244268
1411:4324099
1271:History
1265:allergy
708:mugwort
690:ragweed
688:Weeds:
671:Poaceae
639:dogwood
600:Bet V I
577:Populus
553:Corylus
490:pollens
420:itching
375:allergy
6438:Portal
6395:000813
6349:607154
6262:WHO-EM
5453:Fungal
5107:Asthma
4920:larynx
4849:tonsil
4631:(I+IV)
4363:Type V
4201:Peanut
4130:Type I
3987:sesame
3952:garlic
3947:fruits
3790:Asthma
3732:Curlie
3726:
3717:Curlie
3663:
3655:
3620:
3610:
3569:
3542:
3507:
3497:
3400:
3390:
3351:
3310:
3302:
3267:
3226:
3197:
3169:
3159:
3090:
3020:nhs.uk
2986:
2961:
2953:
2918:
2910:
2831:
2793:
2785:
2677:
2667:
2626:
2618:
2567:
2557:
2549:
2510:
2500:
2461:
2453:
2417:
2409:
2371:
2363:
2269:
2218:
2189:
2180:
2153:
2112:
2083:
2056:
2046:
2038:
1999:
1989:
1981:
1903:
1853:
1740:
1698:
1634:
1608:
1418:
1408:
1277:Rhazes
1040:, and
984:asthma
802:CTLA-4
798:PTPN22
781:models
776:asthma
772:IL1RL1
768:T cell
676:Lolium
658:spruce
650:cherry
629:, red
616:hinoki
614:) and
547:Cedrus
535:Betula
502:plants
494:haying
358:, and
323:and a
286:asthma
282:pollen
216:Nasal
160:Asthma
146:Causes
69:Pollen
6371:31140
5588:Other
5537:Lobar
5488:Lipid
5409:Viral
5308:Other
5070:acute
5047:LRTIs
4972:(LPR)
4950:(LPR)
4928:Croup
4908:(LPR)
4742:URTIs
4470:Lupus
4221:Wheat
4138:atopy
4007:wheat
3956:meat
3711:‹The
3661:S2CID
3308:S2CID
2959:S2CID
2916:S2CID
2791:S2CID
2624:S2CID
2459:S2CID
2415:S2CID
2369:S2CID
2186:INIST
1560:NIAID
1521:NIAID
1488:NIAID
1453:NIAID
1332:NIAID
1210:, an
1169:Other
829:(Ig)
723:Rumex
631:maple
589:Tilia
571:Salix
541:Alnus
529:Morus
523:Pinus
469:Cause
333:fever
315:from
292:, or
6355:MeSH
6344:OMIM
6333:9-CM
5767:SARS
5570:NSIP
5315:ARDS
5116:AERD
5091:COPD
4877:Neck
4782:nose
4757:Head
4671:APS2
4666:APS1
4580:GVHD
4267:ADCC
4196:Milk
4120:and
3982:rice
3972:milk
3942:fish
3937:eggs
3932:corn
3830:Skin
3696:2022
3653:PMID
3618:PMID
3594:2019
3567:PMID
3540:PMID
3505:PMID
3483:2007
3460:2019
3398:PMID
3376:2018
3349:PMID
3300:PMID
3265:PMID
3235:2024
3224:PMID
3195:ISBN
3167:PMID
3145:2010
3122:2023
3088:PMID
3032:2019
3002:2019
2984:ISBN
2951:PMID
2908:PMID
2871:2008
2845:2020
2829:PMID
2783:PMID
2731:2019
2675:PMID
2616:PMID
2565:PMID
2547:ISSN
2508:PMID
2451:PMID
2407:PMID
2361:PMID
2330:2014
2301:2014
2267:ISBN
2248:2014
2216:ISBN
2178:PMID
2151:PMID
2110:PMID
2081:ISBN
2054:PMID
2036:ISSN
1997:PMID
1979:ISSN
1917:2018
1901:PMID
1851:ISBN
1824:2016
1778:2015
1738:ISBN
1714:2016
1696:ISBN
1668:2022
1632:ISBN
1606:PMID
1572:2015
1533:2015
1500:2015
1465:2015
1416:PMID
1344:2015
1246:and
1100:and
1073:and
1046:Mite
982:and
958:and
899:and
744:loci
662:plum
608:sugi
595:Olea
301:mold
6338:477
6329:ICD
6323:J30
6314:ICD
5828:R01
5560:DIP
5555:UIP
5547:IIP
4280:IgM
4275:IgG
4211:Soy
4191:Egg
4143:IgE
3997:soy
3730:at
3645:doi
3641:157
3608:PMC
3598:doi
3532:doi
3528:117
3495:PMC
3487:doi
3425:doi
3388:PMC
3380:doi
3339:doi
3335:127
3292:doi
3257:doi
3157:PMC
3149:doi
3078:doi
3074:108
2943:doi
2898:doi
2775:doi
2694:CPB
2665:PMC
2655:doi
2608:doi
2555:PMC
2539:doi
2498:PMC
2490:doi
2443:doi
2399:doi
2353:doi
2141:doi
2137:108
2044:PMC
2028:doi
1987:PMC
1971:doi
1808:doi
1598:doi
1594:125
1406:PMC
1398:doi
1394:372
1289:hay
1157:or
964:IgE
706:),
654:fir
392:hay
6464::
6422::
6411:,
6404::
6393::
6369::
6358::
6347::
6336::
6321::
6318:10
6275::
6245:,
6241:,
6237:,
6233:,
6229:,
6225:,
6070:,
5575:RB
4365:"/
3724:.›
3686:.
3659:.
3651:.
3639:.
3616:.
3606:.
3592:.
3588:.
3563:18
3561:.
3538:.
3526:.
3503:.
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3477:.
3450:.
3446:.
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3419:.
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3374:.
3370:.
3347:.
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3329:.
3306:.
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3286:.
3263:.
3253:40
3251:.
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3179:^
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3086:.
3072:.
3068:.
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2861:.
2835:.
2825:20
2823:.
2819:.
2803:^
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2769:.
2757:^
2747:.
2721:.
2706:^
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2696:.
2673:.
2663:.
2649:.
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