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Psoriatic onychodystrophy

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37: 150:. A 2005 study proposed a modified NAPSI scale for persons with psoriasis and named the title of their publication "Modification of the Nail Psoriasis Severity Index". Then, in 2007, a study found that there was a high level of inter-rater variability of the 2003 NAPSI scale and proposed another index which was, like the 2005 article, a modification of the 2003 article, and was named modified NAPSI. 122:
separation of the nail from the underlying nail bed, often in thin streaks from the tip-edge to the cuticle; sharp peaked "roof-ridge" raised lines from cuticle to tip; or separation of superficial layers of the nail followed by loss of patches of these superficial layers, leaving thin red nails beneath; or nail pitting–punctate changes along the nail plate surface.
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Psoriatic nails are characterized by a translucent discolouration in the nail bed that resembles a drop of oil beneath the nail plate. Early signs that may accompany the "oil drop" include thickening of the lateral edges of the nail bed with or without resultant flattening or concavity of the nail;
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Rigopoulos, D.; Gregoriou, S.; Daniel, III, C. R.; Belyayeva, H.; Larios, G.; Verra, P.; Stamou, C.; Kontochristopoulos, G.; Avgerinou, G.; Katsambas, A. (2009). "Treatment of Nail Psoriasis with a Two-Compound Formulation of Calcipotriol plus Betamethasone Dipropionate Ointment".
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Cassell, S.; Bieber, J.; Rich, P.; Tutuncu, Z.; Lee, S.; Kalunian, K.; Wu, C.; Kavanaugh, A. (2007). "The modified Nail Psoriasis Severity Index: Validation of an instrument to assess psoriatic nail involvement in patients with psoriatic arthritis".
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Rigopoulos, D.; Gregoriou, S.; Stratigos, A.; Larios, G.; Korfitis, C.; Papaioannou, D.; Antoniou, C.; Ioannides, D. (2008). "Evaluation of the efficacy and safety of infliximab on psoriatic nails: An unblinded, nonrandomized, open-label study".
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Results from low-dose acitretin therapy show NAPSI score reductions comparable with those studies evaluating biologic drugs for nail psoriasis and suggest that low-dose systemic acitretin should be considered in the treatment of nail
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There exist numerous treatments for nail psoriasis but there is little information concerning their effectiveness and safety. Treatments include topical, intralesional, radiation, systemic, and combination therapies.
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The Nail Psoriasis Severity Index (NAPSI) is a numeric, reproducible, objective, simple tool for evaluation of nail psoriasis. It evaluates several signs separately, each on a 1–3 scale: pitting,
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Jiaravuthisan, M. M.; Sasseville, D.; Vender, R. B.; Murphy, F.; Muhn, C. Y. (2007). "Psoriasis of the nail: Anatomy, pathology, clinical presentation, and a review of the literature on therapy".
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Cannavò, S. P.; Guarneri, F.; Vaccaro, M.; Borgia, F.; Guarneri, B. (2003). "Treatment of Psoriatic Nails with Topical Cyclosporin: A Prospective, Randomized Placebo-Controlled Study".
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de Vries, Anna Christa Q; Bogaards, Nathalie A; Hooft, Lotty; Velema, Marieke; Pasch, Marcel; Lebwohl, Mark; Spuls, Phyllis I (2013-01-31).
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Kaçar, N.; Ergin, Ş.; Erdo?an, B. (2007). "The comparison of Nail Psoriasis Severity Index with a less time-consuming qualitative system".
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Kouskoukis, C.; Scher, R.; Ackerman, A. (1983). "The "oil drop" sign of psoriatic nails. A clinical finding specific for psoriasis".
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Velema, Marieke; Hooft, Lotty; Lebwohl, Mark; Spuls, Phyllis I (2009). Spuls, Phyllis I (ed.). "Interventions for nail psoriasis".
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Fiallo, P. (2009). "Yellow nails as an adverse reaction to the topical use of 5-fluorouracil for the treatment of nail psoriasis".
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As of April 2009, an assessment of the evidence for the efficacy and safety of the treatments for nail psoriasis is in progress.
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A 2008 study found that Cannavo's qualitative system correlated with NAPSI (p<0.001) and is less time-consuming.
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for "A Study of the Safety and Efficacy of Golimumab in Patients With Active Psoriatic Arthritis (GO-REVEAL)" at
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A 2013 meta-analysis showed improvement of nail psoriasis with infliximab, golimumab, superficial radiotherapy,
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Lamerson, C.; Stevens, G.; Sax, K. (2008). "Treatment of nail psoriasis with efalizumab: A preliminary study".
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Balbás, G. M.; Regaña, M. S.; Millet, P. U. (2009). "Tacalcitol ointment for the treatment of nail psoriasis".
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Rich, P.; Scher, R. (2003). "Nail Psoriasis Severity Index: A useful tool for evaluation of nail psoriasis".
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for "Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis" at
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Saleem, K.; Azim, W. (2008). "Treatment of nail psoriasis with a modified regimen of steroid injections".
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Parrish, CA; Sobera, JO; Elewski, BE (October 2005). "Modification of the Nail Psoriasis Severity Index".
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ointment obtains a significant improvement in all nail parameters, both of the matrix and of the bed.
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The causes of nail psoriasis are unknown. It has been suggested that fungi may play a role.
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Available studies lack sufficient power to extrapolate a standardized therapeutic regimen.
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Szepietowski, C.; Salomon, J. (Nov 2007). "Do fungi play a role in psoriatic nails?".
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Infliximab appears to be the most effective treatment for nail psoriasis to date.
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for "Effects of Etanercept on Nail Psoriasis and Plaque Psoriasis" at
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Noiles, K.; Vender, R. (2009). "Nail psoriasis and biologics".
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Journal of the European Academy of Dermatology and Venereology
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Snchez Regaa, M.; Mrquez Balbs, G.; Umbert Millet, P. (2008).
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Journal of the European Academy of Dermatology and Venereology
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treatments have not been well studied but may be beneficial.
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Onycholysis: Separation of the nail plate from the nail bed
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Journal of the College of Physicians and Surgeons Pakistan
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Tzung, T.; Chen, C.; Yang, C.; Lo, P.; Chen, Y. (2008).
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James, William; Berger, Timothy; Elston, Dirk (2005).
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Active clinical trials investigating nail psoriasis:
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Andrews' Diseases of the Skin: Clinical Dermatology
892: 680: 2786:Disseminate and recurrent infundibulofolliculitis 957: 599: 3124: 1773: 636: 1890:Congenital onychodysplasia of the index fingers 1729:Lichenoid reaction of graft-versus-host disease 807: 895:Cutis; Cutaneous Medicine for the Practitioner 648:Journal of the American Academy of Dermatology 496:Journal of the American Academy of Dermatology 461:Journal of the American Academy of Dermatology 2796:Erythromelanosis follicularis faciei et colli 1759: 1457:Pityriasis lichenoides et varioliformis acuta 1311: 1090: 1088: 1325: 1094: 1766: 1752: 1318: 1304: 1085: 1023: 35: 1166: 1098:Journal of Cutaneous Medicine and Surgery 1068: 825: 741: 458: 196:. A reported side-effect is yellow nails 113:are more likely to have psoriatic nails. 2791:Erosive pustular dermatosis of the scalp 2211:Central centrifugal cicatricial alopecia 1704:Idiopathic eruptive macular pigmentation 375:The American Journal of Dermatopathology 155: 1151:Cochrane Database of Systematic Reviews 3125: 2771:Acrokeratosis paraneoplastica of Bazex 764: 345: 235:Intralesional corticosteroid injection 1747: 1299: 1140: 1138: 1136: 164:There is a risk of misdiagnosis with 2810:Intermittent hair–follicle dystrophy 313:Dose response and safety of topical 240:Relative effectiveness of treatments 190:nail lacquer and tacalcitol ointment 2748:Recurrent palmoplantar hidradenitis 2629:Idiopathic facial aseptic granuloma 2266:Marie Unna hereditary hypotrichosis 985:Lee, Julia Yu-Yun (November 2009). 984: 767:Journal of Dermatological Treatment 683:Journal of Dermatological Treatment 13: 2489:Lupus miliaris disseminatus faciei 2236:Dissecting cellulitis of the scalp 1656:Hepatitis-associated lichen planus 1147:"Interventions for nail psoriasis" 1133: 88:10% to 78% of those with psoriasis 14: 3144: 3133:Conditions of the skin appendages 2753:Neutrophilic eccrine hidradenitis 2512:Granulomatous perioral dermatitis 1242: 1370:Pustulosis palmaris et plantaris 935:10.1111/j.1365-2133.2008.08686.x 743:10.1111/j.1468-3083.2008.02679.x 614:10.1111/j.1468-3083.2007.02389.x 502:(4): 745–6, author reply 746–7. 422:10.1111/j.1439-0507.2007.01405.x 387:10.1097/00000372-198306000-00012 2911:Traumatic anserine folliculosis 2624:Granulomatous facial dermatitis 1461:Pityriasis lichenoides chronica 1220: 1202: 1191: 1044: 1017: 978: 913: 886: 842: 801: 758: 717: 674: 1935:Malalignment of the nail plate 1709:Keratosis lichenoides chronica 1699:Erythema dyschromicum perstans 1352:Generalized pustular psoriasis 1159:10.1002/14651858.CD007633.pub2 923:British Journal of Dermatology 593: 550: 522: 487: 452: 401: 366: 105:. It is common in those with 1: 2561:Erythrotelangiectatic rosacea 473:10.1067/S0190-9622(03)00910-1 338: 2814:Keratosis pilaris atropicans 2719:Folliculitis nares perforans 1480:Xanthoerythrodermia perstans 1385:Localized pustular psoriasis 171: 133: 7: 2586:Persistent edema of rosacea 532:The Journal of Rheumatology 321: 307: 286: 278: 116: 10: 3149: 3016:Postmiliarial hypohidrosis 2844:Menkes kinky hair syndrome 2261:Frontal fibrosing alopecia 2070:Staining of the nail plate 1930:Longitudinal erythronychia 1925:Lichen planus of the nails 1661:Lichen planus pemphigoides 1486:Large plaque parapsoriasis 1472:Small plaque parapsoriasis 1380:Annular pustular psoriasis 1288:Nail psoriasis at Medscape 991:Dermatology Online Journal 814:Acta Dermato-Venereologica 660:10.1016/j.jaad.2005.07.073 508:10.1016/j.jaad.2004.11.044 209:betamethasone dipropionate 3098: 3070: 2971: 2960: 2901:Rubinstein–Taybi syndrome 2763: 2731:Pseudofolliculitis barbae 2704: 2651: 2616: 2497: 2353: 2342: 2274: 2102: 2093: 2030:Pterygium inversum unguis 1782: 1689:Lichen ruber moniliformis 1671: 1543: 1533: 1499: 1443: 1431:Seborrheic-like psoriasis 1393: 1342: 1333: 1250: 1061:10.1002/14651858.CD007633 779:10.1080/09546630902773494 695:10.1080/09546630902787585 125: 95:Psoriatic onychodystrophy 84: 76: 66: 58: 48: 44:Psoriasis of the toenails 43: 34: 26: 22:Psoriatic onychodystrophy 21: 2943:Uncombable hair syndrome 2927:Trichorrhexis invaginata 2743:Hidradenitis suppurativa 2601:Periorificial dermatitis 1694:Gianotti–Crosti syndrome 1644:with lupus erythematosis 1515:Pityriasis rubra pilaris 1327:Papulosquamous disorders 355:. (10th ed.). Saunders. 144:subungual hyperkeratosis 2921:Trichomycosis axillaris 2854:Parakeratosis pustulosa 2373:Acne miliaris necrotica 2154:(male-pattern baldness) 2118:noncicatricial alopecia 2040:Purpura of the nail bed 1111:10.2310/7750.2008.08012 2938:Trichostasis spinulosa 2634:Periorbital dermatitis 2551:Papulopustular rosacea 2469:Acne with facial edema 2459:Acne keloidalis nuchae 2246:Folliculitis decalvans 2241:Graham-Little syndrome 1995:Onychoptosis defluvium 1490:Retiform parapsoriasis 1467:Lymphomatoid papulosis 1453:Pityriasis lichenoides 1416:Drug-induced psoriasis 1411:Psoriatic erythroderma 1356:Impetigo herpetiformis 1226:Clinical trial number 1208:Clinical trial number 966:Clinical trial number 161: 80:Medications, radiation 68:Differential diagnosis 3108:Sebaceous hyperplasia 3023:Granulosis rubra nasi 2886:Pityriasis amiantacea 2839:Loose anagen syndrome 2781:Bubble hair deformity 2571:Gram-negative rosacea 2334:Nevoid hypertrichosis 2206:Pseudopelade of Brocq 2085:Twenty-nail dystrophy 1960:Nail–patella syndrome 1940:Median nail dystrophy 1639:with lichen sclerosus 1525:Pityriasis amiantacea 827:10.2340/00015555-0401 159: 2991:Miliaria crystalline 2932:Trichorrhexis nodosa 2201:cicatricial alopecia 2183:Alopecia neoplastica 2178:Trichorrhexis nodosa 1811:Yellow nail syndrome 1724:Lichenoid dermatitis 3090:Fox–Fordyce disease 2875:Pili pseudoannulati 2829:Lichen planopilaris 2806:Hair follicle nevus 2724:Tufted folliculitis 2507:Perioral dermatitis 2256:Triangular alopecia 2173:Lichen planopilaris 2152:Androgenic alopecia 2060:Splinter hemorrhage 2055:Shell nail syndrome 1900:Half and half nails 1476:Digitate dermatosis 1406:Psoriatic arthritis 111:psoriatic arthritis 3011:Occlusion miliaria 3001:Miliaria pustulosa 2891:Plica neuropathica 2591:Rosacea conglobata 2402:Acne medicamentosa 2221:Traumatic alopecia 2075:Subungual hematoma 1520:Pityriasis rotunda 1234:ClinicalTrials.gov 1216:ClinicalTrials.gov 1198:clinicaltrials.gov 1003:10.5070/D32XF4V4PW 974:ClinicalTrials.gov 162: 3120: 3119: 3116: 3115: 2996:Miliaria profunda 2956: 2955: 2948:Woolly hair nevus 2834:Lichen spinulosus 2674:Trichilemmal cyst 2647: 2646: 2566:Glandular rosacea 2519:Phymatous rosacea 2449:Occupational acne 2231:Hot comb alopecia 2216:Pressure alopecia 2193:Alopecia mucinosa 2168:Traction alopecia 2163:Telogen effluvium 1741: 1740: 1737: 1736: 1439: 1438: 1421:Inverse psoriasis 1401:Guttate psoriasis 1374:Pustular bacterid 1283: 1282: 864:10.1159/000202179 571:10.1159/000068469 92: 91: 16:Medical condition 3140: 2969: 2968: 2906:Setleis syndrome 2870:Pili multigemini 2606:Pyoderma faciale 2351: 2350: 2188:Anagen effluvium 2100: 2099: 2035:Pterygium unguis 1955:Muehrcke's lines 1842:Onychotillomania 1768: 1761: 1754: 1745: 1744: 1719:Lichen sclerosus 1714:Kraurosis vulvae 1634:overlap synromes 1541: 1540: 1510:Pityriasis rosea 1426:Napkin psoriasis 1340: 1339: 1320: 1313: 1306: 1297: 1296: 1248: 1247: 1236: 1224: 1218: 1206: 1200: 1195: 1189: 1188: 1170: 1142: 1131: 1130: 1092: 1083: 1082: 1072: 1048: 1042: 1041: 1021: 1015: 1014: 982: 976: 964: 955: 954: 917: 911: 910: 890: 884: 883: 846: 840: 839: 829: 805: 799: 798: 762: 756: 755: 745: 721: 715: 714: 678: 672: 671: 643: 634: 633: 597: 591: 590: 554: 548: 547: 526: 520: 519: 491: 485: 484: 456: 450: 449: 405: 399: 398: 370: 364: 349: 39: 19: 18: 3148: 3147: 3143: 3142: 3141: 3139: 3138: 3137: 3123: 3122: 3121: 3112: 3094: 3066: 2963: 2952: 2925:Trichorrhexis ( 2759: 2700: 2669:Epidermoid cyst 2643: 2612: 2576:Steroid rosacea 2493: 2454:Acne aestivalis 2392:Excoriated acne 2368:Acne conglobata 2345: 2338: 2270: 2107: 2089: 2065:Spotted lunulae 2025:Psoriatic nails 1980:Onychomatricoma 1793:Onychogryphosis 1778: 1776:skin appendages 1772: 1742: 1733: 1684:Lichen striatus 1667: 1529: 1495: 1435: 1389: 1329: 1324: 1293: 1284: 1279: 1278: 1259: 1245: 1240: 1239: 1225: 1221: 1207: 1203: 1196: 1192: 1153:(1): CD007633. 1143: 1134: 1093: 1086: 1055:(1): CD007633. 1049: 1045: 1022: 1018: 983: 979: 965: 958: 918: 914: 891: 887: 847: 843: 806: 802: 763: 759: 722: 718: 679: 675: 644: 637: 598: 594: 555: 551: 527: 523: 492: 488: 457: 453: 406: 402: 371: 367: 350: 346: 341: 324: 310: 289: 281: 242: 174: 136: 128: 119: 99:psoriatic nails 30:Psoriatic nails 17: 12: 11: 5: 3146: 3136: 3135: 3118: 3117: 3114: 3113: 3111: 3110: 3104: 3102: 3096: 3095: 3093: 3092: 3087: 3082: 3076: 3074: 3068: 3067: 3065: 3064: 3063: 3062: 3052: 3051: 3050: 3045: 3040: 3030: 3028:Ross' syndrome 3025: 3020: 3019: 3018: 3013: 3008: 3006:Miliaria rubra 3003: 2998: 2993: 2988: 2986:Colloid milium 2977: 2975: 2966: 2958: 2957: 2954: 2953: 2951: 2950: 2945: 2940: 2935: 2929: 2923: 2918: 2913: 2908: 2903: 2898: 2893: 2888: 2883: 2877: 2872: 2867: 2865:Pili bifurcati 2862: 2856: 2851: 2846: 2841: 2836: 2831: 2826: 2824:Koenen's tumor 2821: 2816: 2811: 2808: 2803: 2798: 2793: 2788: 2783: 2778: 2776:Acroosteolysis 2773: 2767: 2765: 2761: 2760: 2758: 2757: 2756: 2755: 2750: 2745: 2734: 2733: 2728: 2727: 2726: 2721: 2710: 2708: 2702: 2701: 2699: 2698: 2693: 2692: 2691: 2686: 2680:Steatocystoma 2678: 2677: 2676: 2671: 2663:Sebaceous cyst 2658: 2656: 2649: 2648: 2645: 2644: 2642: 2641: 2639:SAPHO syndrome 2636: 2631: 2626: 2620: 2618: 2614: 2613: 2611: 2610: 2609: 2608: 2603: 2593: 2588: 2583: 2581:Ocular rosacea 2578: 2573: 2568: 2563: 2558: 2556:Lupoid rosacea 2553: 2548: 2547: 2546: 2541: 2536: 2531: 2526: 2516: 2515: 2514: 2503: 2501: 2495: 2494: 2492: 2491: 2486: 2481: 2479:Acne necrotica 2476: 2471: 2466: 2464:Acne mechanica 2461: 2456: 2451: 2446: 2444:Acne cosmetica 2441: 2436: 2431: 2430: 2429: 2424: 2419: 2409: 2399: 2397:Acne fulminans 2394: 2389: 2383:Infantile acne 2380: 2375: 2370: 2365: 2359: 2357: 2348: 2340: 2339: 2337: 2336: 2331: 2326: 2325: 2324: 2319: 2314: 2306: 2305: 2304: 2299: 2294: 2286: 2280: 2278: 2276:Hypertrichosis 2272: 2271: 2269: 2268: 2263: 2258: 2249: 2248: 2243: 2238: 2233: 2228: 2226:Tumor alopecia 2223: 2218: 2213: 2208: 2196: 2195: 2190: 2185: 2180: 2175: 2170: 2165: 2160: 2155: 2148: 2147: 2146: 2145: 2140: 2135: 2130: 2113: 2111: 2097: 2091: 2090: 2088: 2087: 2082: 2077: 2072: 2067: 2062: 2057: 2052: 2047: 2042: 2037: 2032: 2027: 2022: 2020:Plummer's nail 2017: 2012: 2007: 2002: 1997: 1992: 1987: 1982: 1977: 1972: 1967: 1962: 1957: 1952: 1947: 1942: 1937: 1932: 1927: 1922: 1917: 1912: 1907: 1902: 1897: 1892: 1887: 1882: 1881: 1880: 1875: 1863: 1862: 1857: 1850: 1849: 1844: 1837: 1836: 1831: 1824: 1823: 1818: 1813: 1808: 1801: 1800: 1795: 1788: 1786: 1780: 1779: 1771: 1770: 1763: 1756: 1748: 1739: 1738: 1735: 1734: 1732: 1731: 1726: 1721: 1716: 1711: 1706: 1701: 1696: 1691: 1686: 1681: 1679:Lichen nitidus 1675: 1673: 1669: 1668: 1666: 1665: 1664: 1663: 1658: 1648: 1647: 1646: 1641: 1631: 1630: 1629: 1624: 1619: 1614: 1604: 1603: 1602: 1597: 1592: 1587: 1582: 1577: 1567: 1566: 1565: 1560: 1549: 1547: 1538: 1531: 1530: 1528: 1527: 1522: 1517: 1512: 1506: 1504: 1497: 1496: 1494: 1493: 1483: 1469: 1464: 1449: 1447: 1441: 1440: 1437: 1436: 1434: 1433: 1428: 1423: 1418: 1413: 1408: 1403: 1397: 1395: 1391: 1390: 1388: 1387: 1382: 1377: 1366:Acropustulosis 1363: 1348: 1346: 1337: 1331: 1330: 1323: 1322: 1315: 1308: 1300: 1291: 1290: 1281: 1280: 1277: 1276: 1260: 1255: 1254: 1252: 1251:Classification 1244: 1243:External links 1241: 1238: 1237: 1219: 1201: 1190: 1132: 1084: 1043: 1016: 977: 956: 929:(2): 453–456. 912: 901:(3): 217–220. 885: 858:(4): 338–341. 841: 820:(3): 279–280. 800: 773:(5): 299–301. 757: 736:(8): 963–969. 716: 689:(5): 308–310. 673: 635: 592: 565:(2): 153–156. 549: 538:(1): 123–129. 521: 486: 467:(2): 206–212. 451: 416:(6): 437–442. 400: 381:(3): 259–262. 365: 343: 342: 340: 337: 336: 335: 330: 323: 320: 319: 318: 309: 306: 305: 304: 297: 288: 285: 280: 277: 257: 256: 252: 241: 238: 237: 236: 233: 227: 222: 217: 212: 202: 197: 194:5-fluorouracil 191: 185: 173: 170: 135: 132: 127: 124: 118: 115: 90: 89: 86: 82: 81: 78: 74: 73: 70: 64: 63: 60: 56: 55: 52: 46: 45: 41: 40: 32: 31: 28: 24: 23: 15: 9: 6: 4: 3: 2: 3145: 3134: 3131: 3130: 3128: 3109: 3106: 3105: 3103: 3101: 3097: 3091: 3088: 3086: 3085:Chromhidrosis 3083: 3081: 3078: 3077: 3075: 3073: 3069: 3061: 3058: 3057: 3056: 3053: 3049: 3046: 3044: 3041: 3039: 3036: 3035: 3034: 3033:Hyperhidrosis 3031: 3029: 3026: 3024: 3021: 3017: 3014: 3012: 3009: 3007: 3004: 3002: 2999: 2997: 2994: 2992: 2989: 2987: 2984: 2983: 2982: 2979: 2978: 2976: 2974: 2970: 2967: 2965: 2959: 2949: 2946: 2944: 2941: 2939: 2936: 2933: 2930: 2928: 2924: 2922: 2919: 2917: 2914: 2912: 2909: 2907: 2904: 2902: 2899: 2897: 2894: 2892: 2889: 2887: 2884: 2881: 2878: 2876: 2873: 2871: 2868: 2866: 2863: 2861: 2860:Pili annulati 2857: 2855: 2852: 2850: 2847: 2845: 2842: 2840: 2837: 2835: 2832: 2830: 2827: 2825: 2822: 2820: 2817: 2815: 2812: 2809: 2807: 2804: 2802: 2799: 2797: 2794: 2792: 2789: 2787: 2784: 2782: 2779: 2777: 2774: 2772: 2769: 2768: 2766: 2762: 2754: 2751: 2749: 2746: 2744: 2741: 2740: 2739: 2736: 2735: 2732: 2729: 2725: 2722: 2720: 2717: 2716: 2715: 2712: 2711: 2709: 2707: 2703: 2697: 2694: 2690: 2687: 2685: 2682: 2681: 2679: 2675: 2672: 2670: 2667: 2666: 2664: 2660: 2659: 2657: 2655: 2650: 2640: 2637: 2635: 2632: 2630: 2627: 2625: 2622: 2621: 2619: 2615: 2607: 2604: 2602: 2599: 2598: 2597: 2594: 2592: 2589: 2587: 2584: 2582: 2579: 2577: 2574: 2572: 2569: 2567: 2564: 2562: 2559: 2557: 2554: 2552: 2549: 2545: 2542: 2540: 2537: 2535: 2532: 2530: 2529:Blepharophyma 2527: 2525: 2522: 2521: 2520: 2517: 2513: 2510: 2509: 2508: 2505: 2504: 2502: 2500: 2496: 2490: 2487: 2485: 2482: 2480: 2477: 2475: 2472: 2470: 2467: 2465: 2462: 2460: 2457: 2455: 2452: 2450: 2447: 2445: 2442: 2440: 2437: 2435: 2432: 2428: 2425: 2423: 2420: 2418: 2415: 2414: 2413: 2410: 2407: 2403: 2400: 2398: 2395: 2393: 2390: 2388: 2387:Neonatal acne 2384: 2381: 2379: 2378:Tropical acne 2376: 2374: 2371: 2369: 2366: 2364: 2363:Acne vulgaris 2361: 2360: 2358: 2356: 2352: 2349: 2347: 2341: 2335: 2332: 2330: 2327: 2323: 2320: 2318: 2315: 2313: 2310: 2309: 2307: 2303: 2300: 2298: 2295: 2293: 2290: 2289: 2287: 2285: 2282: 2281: 2279: 2277: 2273: 2267: 2264: 2262: 2259: 2257: 2254: 2251: 2250: 2247: 2244: 2242: 2239: 2237: 2234: 2232: 2229: 2227: 2224: 2222: 2219: 2217: 2214: 2212: 2209: 2207: 2204: 2202: 2198: 2197: 2194: 2191: 2189: 2186: 2184: 2181: 2179: 2176: 2174: 2171: 2169: 2166: 2164: 2161: 2159: 2158:Hypotrichosis 2156: 2153: 2150: 2149: 2144: 2141: 2139: 2136: 2134: 2131: 2129: 2126: 2125: 2124: 2121: 2119: 2115: 2114: 2112: 2110: 2105: 2101: 2098: 2096: 2092: 2086: 2083: 2081: 2080:Terry's nails 2078: 2076: 2073: 2071: 2068: 2066: 2063: 2061: 2058: 2056: 2053: 2051: 2048: 2046: 2043: 2041: 2038: 2036: 2033: 2031: 2028: 2026: 2023: 2021: 2018: 2016: 2013: 2011: 2008: 2006: 2005:Onychoschizia 2003: 2001: 2000:Onychorrhexis 1998: 1996: 1993: 1991: 1988: 1986: 1985:Onychomycosis 1983: 1981: 1978: 1976: 1975:Onychomadesis 1973: 1971: 1968: 1966: 1965:Onychoatrophy 1963: 1961: 1958: 1956: 1953: 1951: 1948: 1946: 1943: 1941: 1938: 1936: 1933: 1931: 1928: 1926: 1923: 1921: 1918: 1916: 1913: 1911: 1908: 1906: 1903: 1901: 1898: 1896: 1893: 1891: 1888: 1886: 1883: 1879: 1876: 1874: 1871: 1870: 1869: 1865: 1864: 1861: 1858: 1856: 1852: 1851: 1848: 1845: 1843: 1839: 1838: 1835: 1834:Nail clubbing 1832: 1830: 1826: 1825: 1822: 1819: 1817: 1814: 1812: 1809: 1807: 1803: 1802: 1799: 1796: 1794: 1790: 1789: 1787: 1785: 1781: 1777: 1774:Disorders of 1769: 1764: 1762: 1757: 1755: 1750: 1749: 1746: 1730: 1727: 1725: 1722: 1720: 1717: 1715: 1712: 1710: 1707: 1705: 1702: 1700: 1697: 1695: 1692: 1690: 1687: 1685: 1682: 1680: 1677: 1676: 1674: 1670: 1662: 1659: 1657: 1654: 1653: 1652: 1649: 1645: 1642: 1640: 1637: 1636: 1635: 1632: 1628: 1625: 1623: 1620: 1618: 1615: 1613: 1610: 1609: 1608: 1605: 1601: 1598: 1596: 1593: 1591: 1588: 1586: 1583: 1581: 1578: 1576: 1573: 1572: 1571: 1568: 1564: 1561: 1559: 1556: 1555: 1554: 1553:configuration 1551: 1550: 1548: 1546: 1545:Lichen planus 1542: 1539: 1537: 1532: 1526: 1523: 1521: 1518: 1516: 1513: 1511: 1508: 1507: 1505: 1503: 1498: 1491: 1487: 1484: 1481: 1477: 1473: 1470: 1468: 1465: 1462: 1458: 1454: 1451: 1450: 1448: 1446: 1445:Parapsoriasis 1442: 1432: 1429: 1427: 1424: 1422: 1419: 1417: 1414: 1412: 1409: 1407: 1404: 1402: 1399: 1398: 1396: 1392: 1386: 1383: 1381: 1378: 1375: 1371: 1367: 1364: 1361: 1357: 1353: 1350: 1349: 1347: 1345: 1341: 1338: 1336: 1332: 1328: 1321: 1316: 1314: 1309: 1307: 1302: 1301: 1298: 1294: 1289: 1286: 1285: 1275: 1271: 1270: 1266: 1262: 1261: 1258: 1253: 1249: 1235: 1231: 1230: 1223: 1217: 1213: 1212: 1205: 1199: 1194: 1186: 1182: 1178: 1174: 1169: 1164: 1160: 1156: 1152: 1148: 1141: 1139: 1137: 1128: 1124: 1120: 1116: 1112: 1108: 1104: 1100: 1099: 1091: 1089: 1080: 1076: 1071: 1066: 1062: 1058: 1054: 1047: 1039: 1035: 1031: 1027: 1020: 1012: 1008: 1004: 1000: 996: 992: 988: 981: 975: 971: 970: 963: 961: 952: 948: 944: 940: 936: 932: 928: 924: 916: 908: 904: 900: 896: 889: 881: 877: 873: 869: 865: 861: 857: 853: 845: 837: 833: 828: 823: 819: 815: 811: 804: 796: 792: 788: 784: 780: 776: 772: 768: 761: 753: 749: 744: 739: 735: 731: 727: 720: 712: 708: 704: 700: 696: 692: 688: 684: 677: 669: 665: 661: 657: 653: 649: 642: 640: 631: 627: 623: 619: 615: 611: 608:(2): 219–22. 607: 603: 596: 588: 584: 580: 576: 572: 568: 564: 560: 553: 545: 541: 537: 533: 525: 517: 513: 509: 505: 501: 497: 490: 482: 478: 474: 470: 466: 462: 455: 447: 443: 439: 435: 431: 427: 423: 419: 415: 411: 404: 396: 392: 388: 384: 380: 376: 369: 362: 361:0-7216-2921-0 358: 354: 348: 344: 334: 331: 329: 326: 325: 316: 312: 311: 302: 298: 295: 291: 290: 284: 276: 274: 270: 266: 262: 261:electron beam 253: 250: 249: 248: 245: 234: 232: 228: 226: 223: 221: 218: 216: 213: 210: 206: 203: 201: 198: 195: 192: 189: 186: 183: 180: 179: 178: 169: 167: 166:onychomycosis 158: 154: 151: 149: 145: 141: 131: 123: 114: 112: 108: 104: 100: 96: 87: 83: 79: 75: 72:Onychomycosis 71: 69: 65: 61: 57: 53: 51: 47: 42: 38: 33: 29: 25: 20: 3055:Hypohidrosis 3048:Palmoplantar 2916:Trichomegaly 2819:Kinking hair 2738:Hidradenitis 2714:Folliculitis 2706:Inflammation 2595: 2412:Halogen acne 2406:steroid acne 2252: 2199: 2116: 2045:Racquet nail 2015:Pincer nails 1990:Onychophosis 1950:Melanonychia 1920:Ingrown nail 1910:Hapalonychia 1885:Chevron nail 1855:Ingrown nail 1847:Onychophagia 1821:Azure lunula 1806:Beau's lines 1650: 1633: 1627:Vulvovaginal 1622:Peno-ginival 1606: 1575:Hypertrophic 1569: 1552: 1292: 1263: 1227: 1222: 1209: 1204: 1193: 1150: 1102: 1096: 1052: 1046: 1032:(2): 78–81. 1029: 1025: 1019: 994: 990: 980: 967: 926: 922: 915: 898: 894: 888: 855: 851: 844: 817: 813: 803: 770: 766: 760: 733: 729: 719: 686: 682: 676: 651: 647: 605: 601: 595: 562: 558: 552: 535: 531: 524: 499: 495: 489: 464: 460: 454: 413: 409: 403: 378: 374: 368: 352: 347: 333:Nail disease 315:Methotrexate 282: 267:compared to 258: 246: 243: 231:methotrexate 205:Calcipotriol 200:Calcipotriol 175: 163: 152: 140:Beau's lines 137: 129: 120: 103:nail disease 98: 94: 93: 3038:Generalized 2849:Monilethrix 2652:Follicular 2534:Gnathophyma 2474:Pomade acne 2329:Prepubertal 2312:generalised 2308:Congenital 2297:generalised 2138:universalis 2050:Red lunulae 2010:Platonychia 1970:Onycholysis 1945:Mees' lines 1895:Green nails 1866:ungrouped: 1829:Koilonychia 1816:Leukonychia 1791:thickness: 1229:NCT00666354 1211:NCT00581100 1168:2066/118676 1070:2066/118676 969:NCT00265096 852:Dermatology 654:(1): 1–27. 559:Dermatology 299:Effects of 292:Effects of 148:onycholysis 54:Dermatology 27:Other names 3060:Anhidrosis 2880:Pili torti 2801:Hair casts 2524:Rhinophyma 2422:Bromoderma 2253:ungrouped: 1868:Paronychia 1840:behavior: 1798:Onychauxis 1590:Ulcerative 1570:morphology 1502:pityriasis 1105:(1): 1–5. 339:References 294:Etanercept 265:grenz rays 255:psoriasis. 220:Infliximab 215:Efalizumab 188:Clobetasol 182:Tacalcitol 3100:Sebaceous 3080:Body odor 3043:Gustatory 2764:Ungrouped 2689:multiplex 2617:Ungrouped 2539:Metophyma 2484:Blackhead 2427:Chloracne 2417:Iododerma 2344:Acneiform 2317:localised 2302:patterned 2292:localised 2288:Acquired 2284:Hirsutism 2104:Hair loss 1915:Hook nail 1860:Anonychia 1600:Pigmented 1536:lichenoid 1335:Psoriasis 1177:1465-1858 1053:Protocols 997:(11): 8. 951:205257408 711:208249471 430:0933-7407 328:Psoriasis 301:Golimumab 229:Low dose 225:Golimumab 211:ointment. 172:Treatment 134:Diagnosis 107:psoriasis 85:Frequency 77:Treatment 62:Psoriasis 50:Specialty 3127:Category 3072:Apocrine 2981:Miliaria 2896:Poliosis 2596:variants 2544:Otophyma 2439:Tar acne 2434:Oil acne 2346:eruption 2322:X-linked 2143:Ophiasis 2123:Alopecia 2109:Baldness 1905:Hangnail 1580:Atrophic 1344:Pustular 1185:23440816 1127:26612674 1119:19298765 1079:23440816 1038:18454890 1011:19951644 943:18565184 907:18856162 880:36470967 872:19212110 836:18480933 795:42262387 787:19363737 752:18410337 703:19367480 668:17572277 630:41847018 622:18211416 587:20866096 579:12592084 544:17216680 516:16198816 481:12894066 446:37127086 438:17944702 322:See also 308:Phase II 287:Phase IV 279:Research 117:Symptoms 2973:Eccrine 2684:simplex 2499:Rosacea 2404:(e.g., 2133:totalis 1878:Chronic 1853:other: 1827:shape: 1804:color: 1612:Mucosal 1595:Actinic 1585:Bullous 1558:Annular 410:Mycoses 395:6625117 273:Topical 269:placebo 2964:glands 2858:Pili ( 2128:areata 1651:other: 1563:Linear 1534:Other 1500:Other 1183:  1175:  1125:  1117:  1077:  1036:  1009:  949:  941:  905:  878:  870:  834:  793:  785:  750:  709:  701:  666:  628:  620:  585:  577:  542:  514:  479:  444:  436:  428:  393:  359:  263:, and 126:Causes 59:Causes 2962:Sweat 2696:Milia 2654:cysts 1873:Acute 1672:Other 1617:Nails 1394:Other 1274:L62.8 1123:S2CID 947:S2CID 876:S2CID 791:S2CID 707:S2CID 626:S2CID 583:S2CID 442:S2CID 207:plus 101:is a 2355:Acne 2095:Hair 1784:Nail 1607:site 1181:PMID 1173:ISSN 1115:PMID 1075:PMID 1034:PMID 1007:PMID 939:PMID 903:PMID 868:PMID 832:PMID 783:PMID 748:PMID 699:PMID 664:PMID 618:PMID 575:PMID 540:PMID 512:PMID 477:PMID 434:PMID 426:ISSN 391:PMID 357:ISBN 146:and 1358:) ( 1265:ICD 1163:hdl 1155:doi 1107:doi 1065:hdl 1057:doi 999:doi 931:doi 927:159 860:doi 856:218 822:doi 775:doi 738:doi 691:doi 656:doi 610:doi 567:doi 563:206 504:doi 469:doi 418:doi 383:doi 97:or 3129:: 2665:" 1478:, 1459:, 1272:: 1269:10 1179:. 1171:. 1161:. 1149:. 1135:^ 1121:. 1113:. 1103:13 1101:. 1087:^ 1073:. 1063:. 1030:18 1028:. 1005:. 995:15 993:. 989:. 959:^ 945:. 937:. 925:. 899:82 897:. 874:. 866:. 854:. 830:. 818:88 816:. 812:. 789:. 781:. 771:20 769:. 746:. 734:22 732:. 728:. 705:. 697:. 687:20 685:. 662:. 652:57 650:. 638:^ 624:. 616:. 606:22 604:. 581:. 573:. 561:. 536:34 534:. 510:. 500:53 498:. 475:. 465:49 463:. 440:. 432:. 424:. 414:50 412:. 389:. 377:. 168:. 142:, 2934:) 2882:) 2661:" 2408:) 2385:/ 2203:: 2120:: 2106:/ 1767:e 1760:t 1753:v 1492:) 1488:( 1482:) 1474:( 1463:) 1455:( 1376:) 1372:( 1368:/ 1362:) 1354:( 1319:e 1312:t 1305:v 1267:- 1257:D 1187:. 1165:: 1157:: 1129:. 1109:: 1081:. 1067:: 1059:: 1040:. 1013:. 1001:: 953:. 933:: 909:. 882:. 862:: 838:. 824:: 797:. 777:: 754:. 740:: 713:. 693:: 670:. 658:: 632:. 612:: 589:. 569:: 546:. 518:. 506:: 483:. 471:: 448:. 420:: 397:. 385:: 379:5 363:. 317:. 303:. 296:.

Index

A picture of a pair of feet in sandals. Some of the nails appear diseased.
Specialty
Differential diagnosis
nail disease
psoriasis
psoriatic arthritis
Beau's lines
subungual hyperkeratosis
onycholysis

onychomycosis
Tacalcitol
Clobetasol
5-fluorouracil
Calcipotriol
Calcipotriol
betamethasone dipropionate
Efalizumab
Infliximab
Golimumab
methotrexate
electron beam
grenz rays
placebo
Topical
Etanercept
Golimumab
Methotrexate
Psoriasis
Nail disease

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