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Radiobiology

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to monitor the effects of radiation in patients of varying proximities to the blast itself, leading to the establishment of three recorded stages of the syndrome. Within 25–30 days of the explosion, the Red Cross surgeon noticed a sharp drop in white blood cell count and established this drop, along with symptoms of fever, as prognostic standards for Acute Radiation Syndrome. Actress
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High radiation dose gives rise to deterministic effects which reliably occur above a threshold, and their severity increases with dose. Deterministic effects are not necessarily more or less serious than stochastic effects; either can ultimately lead to a temporary nuisance or a fatality. Examples of
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The risk for developing radiation-induced cancer at some point in life is greater when exposing a fetus than an adult, both because the cells are more vulnerable when they are growing, and because there is much longer lifespan after the dose to develop cancer. If there is too much radiation exposure
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resulted in a large number of incidents of radiation poisoning, allowing for greater insight into its symptoms and dangers. Red Cross Hospital surgeon Dr. Terufumi Sasaki led intensive research into the Syndrome in the weeks and months following the Hiroshima bombings. Sasaki and his team were able
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When radioactive compounds enter the human body, the effects are different from those resulting from exposure to an external radiation source. Especially in the case of alpha radiation, which normally does not penetrate the skin, the exposure can be much more damaging after ingestion or inhalation.
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with a latent period of years or decades after exposure. The mechanism by which this occurs is well understood, but quantitative models predicting the level of risk remain controversial. The most widely accepted model posits that the incidence of cancers due to ionizing radiation increases linearly
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have been monitoring the health status of the survivors and their descendants since 1946. They have found that radiation exposure increases cancer risk, but also that the average lifespan of survivors was reduced by only a few months compared to those not exposed to radiation. No health effects of
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is a measure of the stochastic health risk due to an intake of radioactive material into the human body. The ICRP states "For internal exposure, committed effective doses are generally determined from an assessment of the intakes of radionuclides from bioassay measurements or other quantities. The
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are an average of about 20 times more dangerous, and in some experiments up to 1000 times more dangerous than an equivalent activity of beta emitting or gamma emitting radioisotopes. If the radiation type is not known, it can be determined by differential measurements in the presence of electrical
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where a radioisotope is used as a drug (usually a liquid or pill). A review of this topic was published in 1999. Because the radioactive material becomes intimately mixed with the affected object it is often difficult to decontaminate the object or person in a case where internal exposure is
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Quantitative data on the effects of ionizing radiation on human health is relatively limited compared to other medical conditions because of the low number of cases to date, and because of the stochastic nature of some of the effects. Stochastic effects can only be measured through large
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both of these produce closely spaced ionizing radiation. This concept is described as a binary system using two separate components for the therapy of cancer. Each component in itself is relatively harmless to the cells, but when combined for treatment they produce a highly cytocidal
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The human body cannot sense ionizing radiation except in very high doses, but the effects of ionization can be used to characterize the radiation. Parameters of interest include disintegration rate, particle flux, particle type, beam energy, kerma, dose rate, and radiation dose.
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Internal exposure occurs when the radioactive material enters the organism, and the radioactive atoms become incorporated into the organism. This can occur through inhalation, ingestion, or injection. Below are a series of examples of internal exposure.
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summarises the recommendations of the ICRU and ICRP on the use of dose quantities and includes a guide to the effects of ionizing radiation as measured in sieverts, and gives examples of approximate figures of dose uptake in certain situations.
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over several years; his death drew public attention to dangers of radiation. By the 1930s, after a number of cases of bone necrosis and death in enthusiasts, radium-containing medical products had nearly vanished from the market.
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stochastic effects, i.e., cancer and heritable effects involving either cancer development in exposed individuals owing to mutation of somatic cells or heritable disease in their offspring owing to mutation of reproductive (germ)
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A schematic diagram showing a rectangle being irradiated by radioactive contamination (shown in red) which is present on an external surface such as the skin; this emits radiation (shown in yellow), which can enter the animal's
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A nuclear worker whose hands have been dirtied with radioactive dust. Assuming that his hands are cleaned before any radioactive material can be absorbed, inhaled or ingested, skin contamination is considered to be external
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The US National Academy of Sciences Biological Effects of Ionizing Radiation Committee "has concluded that there is no compelling evidence to indicate a dose threshold below which the risk of tumor induction is zero".
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epidemiological studies where enough data has been collected to remove confounding factors such as smoking habits and other lifestyle factors. The richest source of high-quality data comes from the study of Japanese
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matrix might never be able to truly become part of an organism, it is normal to consider such particles in the lungs and digestive tract as a form of internal contamination which results in internal exposure.
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External exposure is exposure which occurs when the radioactive source (or other radiation source) is outside (and remains outside) the organism which is exposed. Examples of external exposure include:
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Although radiation was discovered in late 19th century, the dangers of radioactivity and of radiation were not immediately recognized. Acute effects of radiation were first observed in the use of
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to the neutron energy spectrum suitable for BNCT treatment. The tumor is selectively bombarded with these neutrons. The neutrons quickly slow down in the body to become low energy
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are used, and appropriate dose factors and coefficients are used to calculate these from the absorbed dose. Equivalent and effective dose quantities are expressed in units of the
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intentionally subjected his fingers to X-rays in 1895. He published his observations concerning the burns that developed, though he misattributed them to ozone, a
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there could be harmful effects on the unborn child or reproductive organs. Research shows that scanning more than once in nine months can harm the unborn child.
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When alpha particle emitting isotopes are ingested, they are far more dangerous than their half-life or decay rate would suggest. This is due to the high
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of alpha radiation to cause biological damage after alpha-emitting radioisotopes enter living cells. Ingested alpha emitter radioisotopes such as
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spoke out against this sort of treatment, warning that the effects of radiation on the human body were not well understood. Curie later died of
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produced in air by X-rays. Other free radicals produced within the body are now understood to be more important. His injuries healed later.
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Zhang, Zhuoli; Qi, Li; Meinel, Felix G.; Zhou, Chang Sheng; Zhao, Yan E.; Schoepf, U. Joseph; Zhang, Long Jiang; Lu, Guang Ming (2014).
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Before the biological effects of radiation were known, many physicians and corporations had begun marketing radioactive substances as
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concluded that these newly discovered rays not only photograph, but also "affect the living function". At the same time, Pierre and
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which implies that biological effects have been taken into account. These are usually in accordance with the recommendations of the
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deterministic effects (harmful tissue reactions) due in large part to the killing or malfunction of cells following high doses; and
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The interactions between organisms and electromagnetic fields (EMF) and ionizing radiation can be studied in a number of ways:
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to estimate, and the irradiated organism does not become radioactive, except for a case where the radiation is an intense
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A schematic diagram showing a rectangle being irradiated by an external source (in red) of radiation (shown in yellow)
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is the most hazardous source of radiation to general public health, followed by medical imaging as a close second.
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In general, ionizing radiation is harmful and potentially lethal to living beings but can have health benefits in
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The genetic effects of radiation, including the effects on cancer risk, were recognized much later. In 1927
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in the 1940s, heightened scientific attention was given to the study of all manner of radiation effects.
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or charged ions. Biological samples can be irradiated using either a broad, uniform beam, or using a
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More generally, the 1930s saw attempts to develop a general model for radiobiology. Notable here was
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Most adverse health effects of radiation exposure may be grouped in two general categories:
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are captured by the injected boron-10, forming excited (boron-11) which breaks down into
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The Institute for Radiation Biology at the Helmholtz-Center for Environmental Health
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The 2007 Recommendations of the International Commission on Radiological Protection
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radiation dose is determined from the intake using recommended dose coefficients".
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Radiobiology experiments typically make use of a radiation source which could be:
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Possible deterministic effects include of radiation exposure in pregnancy include
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Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII Phase 2
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The added lifetime risk of developing cancer by a single abdominal CT of 8 
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Ronckers, Cécile M; Erdmann, Christine A; Land, Charles E (23 November 2004).
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called X-rays. After irradiating frogs and insects with X-rays in early 1896,
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The monitoring and calculation of doses to safeguard human health is called
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of years or decades after exposure. High doses can cause visually dramatic
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tagged chemical that preferentially binds to tumor cells. Neutrons from a
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The exposure to the ingestion of a soluble radioactive substance, such as
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Ratnapalan, Savithiri; Bentur, Yedidia; Koren, Gideon (2 December 2008).
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Ratnapalan, Savithiri; Bentur, Yedidia; Koren, Gideon (2 December 2008).
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published research showing genetic effects, and in 1946 was awarded the
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United Nations Scientific Committee on the Effects of Atomic Radiation
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uptake and the use of bio-assay for ingested dose. The article on the
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External dose quantities used in radiation protection. See article on
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seems to be particularly high for radiation doses during pregnancy.
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G.Gordon Steel, "Basic Clinical Radiobiology". 2002. Hodder Arnold.
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any sort have thus far been detected in children of the survivors.
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discovered the radioactive polonium and radium later used to treat
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Brisbane, Wayne; Bailey, Michael R.; Sorensen, Mathew D. (2016).
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treatments, and radium-containing waters to be drunk as tonics.
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fields, magnetic fields, or with varying amounts of shielding.
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As a field of medical sciences, radiobiology originated from
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International Commission on Radiation Units and Measurements
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International Commission on Radiation Units and Measurements
2480:"Radiation and breast cancer: a review of current evidence" 1631: 1080: 945:
The intellectual deficit has been estimated to be about 25
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Pattison JE, Hugtenburg RP, Beddoe AH, Charles MW (2001).
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are all stochastic effects induced by ionizing radiation.
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National Council on Radiation Protection and Measurements
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Other important organizations studying the topic include
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These effects are sometimes relevant when deciding about
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per 1,000 mGy at 10 to 17 weeks of gestational age.
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Christensen DM, Iddins CJ, Sugarman SL (February 2014).
2882:(2nd ed.). Cambridge: Cambridge University Press. 1974:- the electromagnetic properties of living systems and 1642:
occurring. While some very insoluble materials such as
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A person who is being treated for cancer by means of a
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Some effects of ionizing radiation on human health are
2955:"A Glow in the Dark, and a Lesson in Scientific Peril" 2609: 1801:
In the United States, the experience of the so-called
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American Congress of Obstetricians and Gynecologists
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International Commission on Radiological Protection
3189: 2953: 2797: 2735: 2575:Unless otherwise specified in boxes, reference is: 2258: 2228: 2175: 1697:The radiation exposure is normally expressed as a 1140:Institut de radioprotection et de sûreté nucléaire 1051:is sometimes also used, predominantly in the USA. 2666: 2387:""Doctor, will that x-ray harm my unborn child?"" 2328:""Doctor, will that x-ray harm my unborn child?"" 2169: 2167: 2165: 967:Also, the risk for the mother of later acquiring 4047: 2612:"An overview of kidney stone imaging techniques" 2104:Biological effects of radiation on the epigenome 2086:, focused down to cellular or subcellular sizes. 2047:Radiation sources for experimental radiobiology 1339:CT of the chest, lung cancer screening protocol 1081:International Committee on Radiation Protection 2945: 2162: 201:effects are those that reliably occur above a 27:Study of effects of radiation on living things 3655: 3175: 1821:as a field of study. With the development of 1257: 1236: 222:, from radiation to a particular body surface 2603: 3821:Airborne radioactive particulate monitoring 3134:. ICRP Publication 103. Ann. ICRP 37 (2-4). 2733: 2660: 2265:. National Academy of Science. p. 10. 2177:"Ionizing radiation injuries and illnesses" 1408:CT of abdomen and pelvis, low dose protocol 3662: 3648: 3182: 3168: 3022:Medicine: A Treasury of Art and Literature 3019: 2983:Radium in Humans: A Review of U.S. Studies 1264: 1250: 205:, and their severity increases with dose. 45:that involves the study of the effects of 2936: 2710: 2692: 2643: 2563:, pp. 61–62, paragraphs 104 and 105. 2513: 2495: 2420: 2402: 2361: 2343: 1834:atomic bombings of Hiroshima and Nagasaki 1419:CT of abdomen and pelvis, with + without 1031:representing the mean energy imparted to 831:atomic bombings of Hiroshima and Nagasaki 184:is estimated to be 0.05%, or 1 in 2,000. 144:Its most common impact is the stochastic 3669: 2902: 2734:Wynn, Volkert; Hoffman, Timothy (1999). 1169: 1161: 990:and is undertaken within the science of 791: 762: 2979: 2905:"Actions of Radiations on Living Cells" 2571: 2569: 2206:Note: first page available free at URL. 1191:A space traveller who is irradiated by 1019:Absorbed, equivalent and effective dose 994:. Key measurement tools are the use of 771: 14: 4048: 3523:Wireless electronic devices and health 2580:"Radiation Dose in X-Ray and CT Exams" 2452: 2450: 2448: 2446: 2444: 2442: 2440: 1245:Effective dose by medical imaging type 3986:Radiation Protection Convention, 1960 3643: 3163: 2951: 2879:Actions of Radiations on Living Cells 2589:Radiological Society of North America 2007:functional magnetic resonance imaging 1850:Radiation Effects Research Foundation 1817:, a key step in the establishment of 837:has been necessary during pregnancy: 800:on how these are calculated and used. 3549:List of civilian radiation accidents 3518:Wireless device radiation and health 3513:Biological dose units and quantities 3463:Electromagnetic radiation and health 2795: 2566: 2560: 2548: 2536: 2247:Note: First paragraph provided free. 2215: 2156: 1967:Electromagnetic radiation and health 1900:electromagnetic radiation and health 1856: 1152: 1146:European Committee on Radiation Risk 534:Cognitive impairment > 24 h 2903:Mitchell, J. S. (2 November 1946). 2872: 2490:(1). BMC (Springer Nature): 21–32. 2437: 1732:using the newly discovered form of 385:— (patients die in < 48 h) 41:) is a field of clinical and basic 24: 3498:Radioactivity in the life sciences 3138: 3092:10.1093/oxfordjournals.rpd.a006532 2737:"Therapeutic Radiopharmaceuticals" 2306:Merck Manuals Professional Edition 2257:National Research Council (2006). 25: 4077: 1997:Transcranial magnetic stimulation 1054:To represent stochastic risk the 778:relative biological effectiveness 531:Cognitive impairment 6–20 h 88: 3146:Radiobiology for the Radiologist 2952:Grady, Denise (6 October 1998). 2748:(9). ACS Publications: 2269–92. 2622:(11). Springer Nature: 654–662. 2237:. Harvard University. March 2013 1221:External exposure is relatively 1090: 964:exposes the fetus to radiation. 692: 384: 187: 97:for the treatment of cancer and 77:. Controlled doses are used for 73:, and/or rapid fatality through 61:. Its most common impact is the 57:for the treatment of cancer and 49:on living things, in particular 3086:(2). Oxford Academic: 125–136. 3064: 3038: 3013: 2986:. Argonne National Laboratory. 2973: 2896: 2866: 2844: 2838: 2804:Physics in Medicine and Biology 2789: 2768: 2727: 2119:NASA Space Radiation Laboratory 1846:Atomic Bomb Casualty Commission 1789:caused by radiation poisoning. 804: 216:, by acute whole-body radiation 177:varies greatly across species. 3753:Computed tomography dose index 3080:Radiation Protection Dosimetry 2853:British Institute of Radiology 2378: 2319: 2294: 2250: 2221: 2114:Health threat from cosmic rays 1135:(NAS through the BEIR studies) 977: 13: 1: 2144: 1654:Boron neutron capture therapy 1473:Lower gastrointestinal series 1460:Upper gastrointestinal series 1184:A person who places a sealed 693:— (patients die in < 48h) 241:Radiation-induced lung injury 226:Radiation-induced thyroiditis 116: 2694:10.1371/journal.pone.0099112 2539:, p. 73, paragraph 144. 1656:(BNCT) involves injecting a 1197:A person who is treated for 1133:National Academy of Sciences 1027:is a physical dose quantity 954:medical imaging in pregnancy 398:None to mild (< 10%) 7: 3386:Cosmic background radiation 3020:Carmichael, Ann G. (1991). 2849:"Radiobiology in the 1940s" 2230:"Do CT scans cause cancer?" 2218:, p. 55, Paragraph 83. 2159:, p. 49, paragraph 55. 2097: 1601: 1157: 486:Moderate increase (10–100%) 237:, from long-term radiation. 209:deterministic effects are: 51:health effects of radiation 10: 4082: 4017: 3615: 3473:Lasers and aviation safety 3124: 2816:10.1088/0031-9155/21/3/001 2003:Magnetic resonance imaging 1704: 1237:By type of medical imaging 856:Estimated threshold dose ( 755:2 days – 2 weeks 314: 235:Chronic radiation syndrome 191: 4015: 3994: 3963: 3912: 3876: 3811: 3728: 3710:Radioactive contamination 3677: 3613: 3577: 3541: 3503:Radioactive contamination 3428: 3356:Electromagnetic radiation 3346: 3258: 3205: 3198: 2235:Harvard Health Publishing 2194:10.1016/j.emc.2013.10.002 1905:Specific absorption rates 1738:Ivan Romanovich Tarkhanov 1734:electromagnetic radiation 1586: 1572: 1558: 1545: 1513: 1484: 1391: 1362: 1322: 1292: 1243: 1127:UK Health Security Agency 884: 881: 697: 489:Moderate to severe (100%) 269: 266: 263: 161:is correct, then natural 4061:Radiation health effects 4018:See also the categories 4007:Radiation-induced cancer 4002:Acute radiation syndrome 3616:See also the categories 3554:1996 Costa Rica accident 3215:Acoustic radiation force 2796:Hall, E J (1 May 1976). 2124:Radioactivity in biology 1396:CT of abdomen and pelvis 1380:Coronary CT calcium scan 1282:Effective dose in adults 958:projectional radiography 874:or none (all or nothing) 214:Acute radiation syndrome 194:Acute radiation syndrome 151:effective radiation dose 127:Radiation-induced cancer 75:acute radiation syndrome 3528:Radiation heat-transfer 3381:Gravitational radiation 2628:10.1038/nrurol.2016.154 2551:, p. 24, glossary. 2188:(1). Elsevier: 245–65. 2182:Emerg Med Clin North Am 2074:generating high energy 1941:- their general nature. 1777:. Examples were radium 1611:The exposure caused by 1367:Coronary CT angiography 934:intellectual disability 917:intellectual disability 827:intellectual disability 685:Electrolyte disturbance 664:Electrolyte disturbance 3858:Semiconductor detector 3814:measurement techniques 3569:1990 Zaragoza accident 3564:1984 Moroccan accident 3533:Linear energy transfer 3207:Non-ionizing radiation 2980:Rowland, R.E. (1994). 2616:Nature Reviews Urology 2484:Breast Cancer Research 1713:when German physicist 1176: 1167: 801: 442:Mild to moderate (50%) 153:at a rate of 5.5% per 3877:Protection techniques 3841:Scintillation counter 3559:1987 Goiânia accident 3361:Synchrotron radiation 3351:Earth's energy budget 3333:Radioactive materials 3328:Particle accelerators 2041:Psychoneuroimmunology 2033:Biological psychiatry 2021:Developmental biology 1753:Hermann Joseph Muller 1447:Intravenous pyelogram 1173: 1165: 998:to give the external 795: 537:Rapid incapacitation 404:Heavy (> 95%) 401:Heavy (> 10%) 192:Further information: 171:atomic bomb survivors 4036:Radiation protection 3853:Radiation monitoring 3846:Proportional counter 3731:quantities and units 3685:Background radiation 3671:Radiation protection 3630:Radiation protection 3483:Radiation protection 3371:Black-body radiation 3278:Background radiation 3193:(physics and health) 2776:Radiation Biophysics 2072:particle accelerator 1775:radioactive quackery 1287:background radiation 772:By type of radiation 163:background radiation 37:, and uncommonly as 3868:Whole-body counting 3778:Mean glandular dose 3715:Radioactive sources 3600:Radiation hardening 3542:Radiation incidents 3478:Medical radiography 3437:Radiation syndrome 3391:Cherenkov radiation 2921:1946Natur.158..601M 2810:(3). IOP: 347–359. 2685:2014PLoSO...999112Q 2486:(Review article.). 2404:10.1503/cmaj.080247 2345:10.1503/cmaj.080247 2109:Cell survival curve 1976:Bioelectromagnetics 1972:Bioelectromagnetism 1930:Bioelectromagnetics 1911:Radiation poisoning 1898:High and low-level 1871:Radiation chemistry 1639:radiopharmaceutical 1541:5 weeks - 6 months 1285:Equivalent time of 608:Moderate to severe 243:, from for example 146:induction of cancer 63:induction of cancer 3705:Internal dosimetry 3700:Ionizing radiation 3595:Radioactive source 3416:Radiation exposure 3396:Askaryan radiation 3376:Particle radiation 3260:Ionizing radiation 3148:. 2006. Lippincott 2960:The New York Times 2774:Y. B. Kudriashov. 2744:(Review article). 2618:(Review article). 1916:Radiation oncology 1885:Molecular genetics 1759:for his findings. 1520:X-ray of extremity 1229:beam which causes 1186:radioactive source 1177: 1168: 1037:ionizing radiation 900:Growth restriction 823:growth restriction 802: 47:ionizing radiation 4043: 4042: 4024:Radiation effects 3995:Radiation effects 3758:Counts per minute 3637: 3636: 3618:Radiation effects 3488:Radiation therapy 3424: 3423: 3366:Thermal radiation 3303:Neutron radiation 3268:Radioactive decay 3031:978-0-88363-991-7 2915:(4018): 601–602. 2754:10.1021/cr9804386 2585:RadiologyInfo.org 2397:(12): 1293–1296. 2338:(12): 1293–1296. 2280:978-0-309-09156-5 1987:Radiation therapy 1945:Electrophysiology 1920:radiation therapy 1866:Radiation physics 1857:Areas of interest 1666:neutron moderator 1615:present within a 1599: 1598: 1153:Exposure pathways 1043:(Gy). The non-SI 1035:per unit mass by 969:radiation-induced 943: 942: 835:radiation therapy 769: 768: 594:Mild to moderate 245:radiation therapy 135:cognitive decline 95:radiation therapy 55:radiation therapy 35:radiation biology 16:(Redirected from 4073: 3899:Radon mitigation 3894:Potassium iodide 3812:Instruments and 3664: 3657: 3650: 3641: 3640: 3578:Related articles 3493:Radiation damage 3318:Nuclear reactors 3203: 3202: 3184: 3177: 3170: 3161: 3160: 3119: 3118: 3116: 3110:. Archived from 3077: 3068: 3062: 3061: 3059: 3057: 3052:. 11 August 2016 3042: 3036: 3035: 3017: 3011: 3010: 3008: 3006: 2977: 2971: 2970: 2968: 2966: 2957: 2949: 2943: 2942: 2940: 2929:10.1038/158601a0 2900: 2894: 2893: 2870: 2864: 2863: 2861: 2859: 2842: 2836: 2835: 2801: 2793: 2787: 2772: 2766: 2765: 2742:Chemical Reviews 2739: 2731: 2725: 2724: 2714: 2696: 2664: 2658: 2657: 2647: 2607: 2601: 2600: 2598: 2596: 2573: 2564: 2558: 2552: 2546: 2540: 2534: 2528: 2527: 2517: 2499: 2475: 2469: 2467: 2454: 2435: 2434: 2424: 2406: 2382: 2376: 2375: 2365: 2347: 2323: 2317: 2316: 2314: 2312: 2298: 2292: 2291: 2289: 2287: 2264: 2254: 2248: 2246: 2244: 2242: 2232: 2225: 2219: 2213: 2207: 2205: 2179: 2171: 2160: 2154: 2139:Radiosensitivity 1823:nuclear reactors 1819:nuclear medicine 1674:thermal neutrons 1670:thermal neutrons 1664:are shaped by a 1644:fission products 1532:Lower extremity 1266: 1259: 1252: 1241: 1240: 840: 839: 833:and cases where 574:< 7 days 360:< 10 min 261: 260: 253:and infertility. 43:medical sciences 21: 4081: 4080: 4076: 4075: 4074: 4072: 4071: 4070: 4066:Medical physics 4046: 4045: 4044: 4039: 4038: 4020:Medical physics 4011: 3990: 3959: 3908: 3872: 3813: 3807: 3768:Equivalent dose 3730: 3724: 3673: 3668: 3638: 3633: 3632: 3609: 3605:Havana syndrome 3590:Nuclear physics 3573: 3537: 3430: 3420: 3406:Unruh radiation 3342: 3323:Nuclear weapons 3308:Nuclear fission 3254: 3194: 3188: 3141: 3139:Further reading 3127: 3122: 3117:on 16 Jul 2020. 3114: 3075: 3069: 3065: 3055: 3053: 3044: 3043: 3039: 3032: 3018: 3014: 3004: 3002: 2978: 2974: 2964: 2962: 2950: 2946: 2911:(Book review). 2901: 2897: 2890: 2871: 2867: 2857: 2855: 2846:Lea, Douglas E. 2843: 2839: 2794: 2790: 2773: 2769: 2732: 2728: 2665: 2661: 2608: 2604: 2594: 2592: 2578: 2576: 2574: 2567: 2559: 2555: 2547: 2543: 2535: 2531: 2476: 2472: 2456: 2455: 2438: 2383: 2379: 2324: 2320: 2310: 2308: 2300: 2299: 2295: 2285: 2283: 2281: 2255: 2251: 2240: 2238: 2227: 2226: 2222: 2214: 2210: 2172: 2163: 2155: 2151: 2147: 2100: 2057:isotopic source 2049: 1859: 1827:nuclear weapons 1807:Robley D. Evans 1787:aplastic anemia 1771:patent medicine 1715:Wilhelm Röntgen 1707: 1662:nuclear reactor 1648:uranium dioxide 1604: 1503:CT of the spine 1434:CT Colonography 1327:CT of the chest 1309:With + without 1271: 1270: 1239: 1160: 1155: 1093: 1063: 1056:equivalent dose 1021: 980: 844:Gestational age 807: 774: 687: 683: 679: 677:Severe diarrhea 675: 671: 662: 658: 650: 646: 642: 638: 624: 620: 616: 612: 602: 598: 568:28–31 days 448:Severe (80–90%) 230:hyperthyroidism 220:Radiation burns 196: 190: 175:radioresistance 119: 91: 79:medical imaging 71:radiation burns 33:(also known as 28: 23: 22: 15: 12: 11: 5: 4079: 4069: 4068: 4063: 4058: 4041: 4040: 4016: 4013: 4012: 4010: 4009: 4004: 3998: 3996: 3992: 3991: 3989: 3988: 3983: 3978: 3973: 3967: 3965: 3961: 3960: 3958: 3957: 3952: 3947: 3942: 3937: 3932: 3927: 3922: 3916: 3914: 3910: 3909: 3907: 3906: 3901: 3896: 3891: 3886: 3884:Lead shielding 3880: 3878: 3874: 3873: 3871: 3870: 3865: 3860: 3855: 3849: 3848: 3843: 3838: 3833: 3831:Geiger counter 3828: 3823: 3817: 3815: 3809: 3808: 3806: 3805: 3800: 3795: 3790: 3785: 3780: 3775: 3770: 3765: 3763:Effective dose 3760: 3755: 3750: 3748:Committed dose 3745: 3740: 3734: 3732: 3726: 3725: 3723: 3722: 3717: 3712: 3707: 3702: 3697: 3695:Health physics 3692: 3687: 3681: 3679: 3675: 3674: 3667: 3666: 3659: 3652: 3644: 3635: 3634: 3614: 3611: 3610: 3608: 3607: 3602: 3597: 3592: 3587: 3581: 3579: 3575: 3574: 3572: 3571: 3566: 3561: 3556: 3551: 3545: 3543: 3539: 3538: 3536: 3535: 3530: 3525: 3520: 3515: 3510: 3505: 3500: 3495: 3490: 3485: 3480: 3475: 3470: 3465: 3460: 3455: 3453:Health physics 3450: 3449: 3448: 3443: 3434: 3432: 3426: 3425: 3422: 3421: 3419: 3418: 3413: 3411:Dark radiation 3408: 3403: 3401:Bremsstrahlung 3398: 3393: 3388: 3383: 3378: 3373: 3368: 3363: 3358: 3353: 3347: 3344: 3343: 3341: 3340: 3335: 3330: 3325: 3320: 3315: 3313:Nuclear fusion 3310: 3305: 3300: 3295: 3290: 3285: 3283:Alpha particle 3280: 3275: 3270: 3264: 3262: 3256: 3255: 3253: 3252: 3247: 3242: 3237: 3232: 3227: 3222: 3217: 3211: 3209: 3200: 3196: 3195: 3187: 3186: 3179: 3172: 3164: 3158: 3157: 3152: 3149: 3140: 3137: 3136: 3135: 3126: 3123: 3121: 3120: 3063: 3037: 3030: 3012: 2992:10.2172/751062 2972: 2944: 2895: 2888: 2865: 2837: 2788: 2767: 2726: 2659: 2602: 2565: 2553: 2541: 2529: 2497:10.1186/bcr970 2470: 2468:February 2016 2436: 2377: 2318: 2293: 2279: 2271:10.17226/11340 2249: 2220: 2208: 2161: 2148: 2146: 2143: 2142: 2141: 2136: 2131: 2126: 2121: 2116: 2111: 2106: 2099: 2096: 2095: 2094: 2087: 2068: 2048: 2045: 2044: 2043: 2030: 2024: 2010: 2000: 1994: 1989: 1984: 1982:Electrotherapy 1979: 1969: 1963:Magnetobiology 1948: 1942: 1939:Magnetic field 1935:Electric field 1932: 1927: 1913: 1908: 1902: 1896: 1887: 1882: 1873: 1868: 1858: 1855: 1726:Leopold Freund 1706: 1703: 1699:committed dose 1694: 1693: 1685:alpha particle 1651: 1635: 1620: 1603: 1600: 1597: 1596: 1593: 1590: 1584: 1583: 1580: 1577: 1570: 1569: 1566: 1563: 1562:(bone density) 1556: 1555: 1552: 1549: 1543: 1542: 1539: 1536: 1534:CT angiography 1529: 1528: 1525: 1522: 1517: 1511: 1510: 1507: 1504: 1500: 1499: 1496: 1493: 1488: 1482: 1481: 1478: 1475: 1469: 1468: 1465: 1462: 1456: 1455: 1452: 1449: 1443: 1442: 1439: 1436: 1430: 1429: 1426: 1423: 1416: 1415: 1412: 1409: 1405: 1404: 1401: 1398: 1393: 1389: 1388: 1385: 1382: 1376: 1375: 1372: 1369: 1364: 1360: 1359: 1356: 1353: 1347: 1346: 1343: 1340: 1336: 1335: 1332: 1329: 1324: 1320: 1319: 1316: 1313: 1306: 1305: 1302: 1299: 1296: 1294:CT of the head 1290: 1289: 1283: 1280: 1277: 1273: 1272: 1269: 1268: 1261: 1254: 1246: 1244: 1238: 1235: 1219: 1218: 1214: 1211:committed dose 1195: 1189: 1159: 1156: 1154: 1151: 1150: 1149: 1143: 1136: 1129: 1123: 1116: 1110: 1092: 1089: 1066:effective dose 1061: 1020: 1017: 1012:committed dose 1000:effective dose 992:health physics 979: 976: 941: 940: 937: 930: 929:16 to 25 weeks 927: 926:18 to 27 weeks 923: 922: 919: 913: 910: 909:10 to 17 weeks 906: 905: 902: 896: 895: 892: 886: 883: 879: 878: 875: 869: 866: 862: 861: 854: 851: 846: 806: 803: 773: 770: 767: 766: 760: 759: 758:1–2 days 756: 753: 752:2–4 weeks 750: 749:4–6 weeks 747: 746:6–8 weeks 744: 740: 739: 736: 733: 730: 727: 724: 720: 719: 716: 713: 710: 707: 704: 701: 695: 694: 691: 666: 656:disorientation 632: 606: 592: 590: 582: 581: 578: 575: 572: 571:7–28 days 569: 566: 564: 556: 555: 538: 535: 532: 529: 528:No impairment 526: 519: 518: 517:< 1 h 515: 512: 509: 506: 503: 497: 496: 495:Severe (100%) 493: 490: 487: 484: 481: 475: 474: 473:< 1 h 471: 468: 465: 462: 459: 453: 452: 451:Severe (100%) 449: 446: 445:Moderate (80%) 443: 440: 437: 431: 430: 429:< 1 h 427: 424: 421: 418: 415: 409: 408: 405: 402: 399: 396: 393: 387: 386: 383: 382:< 48 h 380: 379:< 48 h 377: 374: 373:< 24 h 371: 365: 364: 361: 358: 357:10–60 min 355: 352: 349: 343: 342: 339: 336: 333: 330: 327: 318: 312: 311: 305: 299: 293: 287: 280: 279: 268: 265: 255: 254: 248: 238: 232: 223: 217: 203:threshold dose 189: 186: 118: 115: 114: 113: 109: 99:thyrotoxicosis 90: 89:Health effects 87: 59:thyrotoxicosis 26: 18:Radiobiologist 9: 6: 4: 3: 2: 4078: 4067: 4064: 4062: 4059: 4057: 4054: 4053: 4051: 4037: 4033: 4029: 4028:Radioactivity 4025: 4021: 4014: 4008: 4005: 4003: 4000: 3999: 3997: 3993: 3987: 3984: 3982: 3979: 3977: 3974: 3972: 3969: 3968: 3966: 3962: 3956: 3953: 3951: 3948: 3946: 3943: 3941: 3938: 3936: 3933: 3931: 3928: 3926: 3923: 3921: 3918: 3917: 3915: 3913:Organisations 3911: 3905: 3902: 3900: 3897: 3895: 3892: 3890: 3887: 3885: 3882: 3881: 3879: 3875: 3869: 3866: 3864: 3861: 3859: 3856: 3854: 3851: 3850: 3847: 3844: 3842: 3839: 3837: 3834: 3832: 3829: 3827: 3824: 3822: 3819: 3818: 3816: 3810: 3804: 3801: 3799: 3796: 3794: 3791: 3789: 3786: 3784: 3781: 3779: 3776: 3774: 3771: 3769: 3766: 3764: 3761: 3759: 3756: 3754: 3751: 3749: 3746: 3744: 3741: 3739: 3738:Absorbed dose 3736: 3735: 3733: 3727: 3721: 3718: 3716: 3713: 3711: 3708: 3706: 3703: 3701: 3698: 3696: 3693: 3691: 3688: 3686: 3683: 3682: 3680: 3678:Main articles 3676: 3672: 3665: 3660: 3658: 3653: 3651: 3646: 3645: 3642: 3631: 3627: 3623: 3622:Radioactivity 3619: 3612: 3606: 3603: 3601: 3598: 3596: 3593: 3591: 3588: 3586: 3583: 3582: 3580: 3576: 3570: 3567: 3565: 3562: 3560: 3557: 3555: 3552: 3550: 3547: 3546: 3544: 3540: 3534: 3531: 3529: 3526: 3524: 3521: 3519: 3516: 3514: 3511: 3509: 3506: 3504: 3501: 3499: 3496: 3494: 3491: 3489: 3486: 3484: 3481: 3479: 3476: 3474: 3471: 3469: 3466: 3464: 3461: 3459: 3456: 3454: 3451: 3447: 3444: 3442: 3439: 3438: 3436: 3435: 3433: 3427: 3417: 3414: 3412: 3409: 3407: 3404: 3402: 3399: 3397: 3394: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3367: 3364: 3362: 3359: 3357: 3354: 3352: 3349: 3348: 3345: 3339: 3336: 3334: 3331: 3329: 3326: 3324: 3321: 3319: 3316: 3314: 3311: 3309: 3306: 3304: 3301: 3299: 3296: 3294: 3291: 3289: 3288:Beta particle 3286: 3284: 3281: 3279: 3276: 3274: 3273:Cluster decay 3271: 3269: 3266: 3265: 3263: 3261: 3257: 3251: 3248: 3246: 3243: 3241: 3238: 3236: 3233: 3231: 3228: 3226: 3223: 3221: 3218: 3216: 3213: 3212: 3210: 3208: 3204: 3201: 3199:Main articles 3197: 3192: 3185: 3180: 3178: 3173: 3171: 3166: 3165: 3162: 3156: 3153: 3150: 3147: 3143: 3142: 3133: 3129: 3128: 3113: 3109: 3105: 3101: 3097: 3093: 3089: 3085: 3081: 3074: 3067: 3051: 3050:Science Daily 3047: 3041: 3033: 3027: 3023: 3016: 3001: 2997: 2993: 2989: 2985: 2984: 2976: 2961: 2956: 2948: 2939: 2934: 2930: 2926: 2922: 2918: 2914: 2910: 2906: 2899: 2891: 2889:9781001281377 2885: 2881: 2880: 2875: 2869: 2854: 2850: 2847: 2841: 2833: 2829: 2825: 2821: 2817: 2813: 2809: 2805: 2800: 2792: 2785: 2784:9781600212802 2781: 2777: 2771: 2763: 2759: 2755: 2751: 2747: 2743: 2738: 2730: 2722: 2718: 2713: 2708: 2704: 2700: 2695: 2690: 2686: 2682: 2679:(6): e99112. 2678: 2674: 2670: 2663: 2655: 2651: 2646: 2641: 2637: 2633: 2629: 2625: 2621: 2617: 2613: 2606: 2591: 2590: 2586: 2581: 2572: 2570: 2562: 2557: 2550: 2545: 2538: 2533: 2525: 2521: 2516: 2511: 2507: 2503: 2498: 2493: 2489: 2485: 2481: 2474: 2465: 2464: 2459: 2453: 2451: 2449: 2447: 2445: 2443: 2441: 2432: 2428: 2423: 2418: 2414: 2410: 2405: 2400: 2396: 2392: 2388: 2381: 2373: 2369: 2364: 2359: 2355: 2351: 2346: 2341: 2337: 2333: 2329: 2322: 2307: 2303: 2297: 2282: 2276: 2272: 2268: 2263: 2262: 2253: 2236: 2231: 2224: 2217: 2212: 2203: 2199: 2195: 2191: 2187: 2183: 2178: 2170: 2168: 2166: 2158: 2153: 2149: 2140: 2137: 2135: 2132: 2130: 2127: 2125: 2122: 2120: 2117: 2115: 2112: 2110: 2107: 2105: 2102: 2101: 2092: 2088: 2085: 2081: 2077: 2073: 2069: 2066: 2062: 2058: 2054: 2053: 2052: 2042: 2038: 2034: 2031: 2028: 2027:Bioenergetics 2025: 2022: 2018: 2014: 2013:Embryogenesis 2011: 2008: 2004: 2001: 1998: 1995: 1993: 1992:Radiogenomics 1990: 1988: 1985: 1983: 1980: 1977: 1973: 1970: 1968: 1964: 1961:imaging) and 1960: 1956: 1952: 1949: 1946: 1943: 1940: 1936: 1933: 1931: 1928: 1925: 1921: 1917: 1914: 1912: 1909: 1906: 1903: 1901: 1897: 1895: 1891: 1888: 1886: 1883: 1881: 1877: 1874: 1872: 1869: 1867: 1864: 1863: 1862: 1854: 1851: 1847: 1842: 1840: 1835: 1830: 1828: 1824: 1820: 1816: 1812: 1808: 1804: 1799: 1796: 1792: 1788: 1784: 1780: 1776: 1772: 1767: 1765: 1760: 1758: 1754: 1749: 1747: 1743: 1739: 1735: 1731: 1727: 1722: 1720: 1716: 1712: 1702: 1700: 1691: 1686: 1683: 1679: 1675: 1671: 1667: 1663: 1659: 1655: 1652: 1649: 1645: 1640: 1636: 1633: 1629: 1625: 1621: 1618: 1614: 1610: 1609: 1608: 1594: 1591: 1589: 1585: 1581: 1578: 1575: 1571: 1567: 1564: 1561: 1557: 1553: 1550: 1548: 1544: 1540: 1538:0.3 - 1.6 mSv 1537: 1535: 1531: 1530: 1526: 1523: 1521: 1518: 1516: 1512: 1508: 1505: 1502: 1501: 1497: 1494: 1492: 1489: 1487: 1483: 1479: 1476: 1474: 1471: 1470: 1466: 1463: 1461: 1458: 1457: 1453: 1450: 1448: 1445: 1444: 1440: 1437: 1435: 1432: 1431: 1427: 1424: 1422: 1421:radiocontrast 1418: 1417: 1413: 1410: 1407: 1406: 1402: 1399: 1397: 1394: 1390: 1386: 1383: 1381: 1378: 1377: 1373: 1370: 1368: 1365: 1361: 1357: 1354: 1352: 1349: 1348: 1344: 1341: 1338: 1337: 1333: 1330: 1328: 1325: 1321: 1317: 1314: 1312: 1311:radiocontrast 1308: 1307: 1303: 1300: 1298:Single series 1297: 1295: 1291: 1288: 1284: 1281: 1278: 1276:Target organs 1275: 1274: 1267: 1262: 1260: 1255: 1253: 1248: 1247: 1242: 1234: 1232: 1228: 1224: 1215: 1212: 1208: 1207:brachytherapy 1204: 1200: 1196: 1194: 1190: 1188:in his pocket 1187: 1183: 1182: 1181: 1172: 1164: 1147: 1144: 1141: 1137: 1134: 1130: 1128: 1124: 1121: 1117: 1114: 1111: 1108: 1105: 1104: 1103: 1100: 1098: 1091:Organizations 1088: 1086: 1082: 1078: 1074: 1070: 1067: 1060: 1057: 1052: 1050: 1046: 1042: 1038: 1034: 1030: 1026: 1025:absorbed dose 1016: 1013: 1008: 1005: 1001: 997: 993: 989: 984: 975: 973: 972:breast cancer 970: 965: 963: 959: 955: 950: 948: 938: 935: 931: 928: 925: 924: 920: 918: 914: 912:8 to 15 weeks 911: 908: 907: 903: 901: 898: 897: 893: 891: 890:birth defects 887: 882:4 to 10 weeks 880: 876: 873: 870: 867: 864: 863: 859: 855: 852: 850: 849:Embryonic age 847: 845: 842: 841: 838: 836: 832: 828: 824: 820: 819:birth defects 817:, structural 816: 811: 799: 794: 790: 787: 783: 779: 765: 761: 757: 754: 751: 748: 745: 742: 741: 737: 734: 731: 728: 725: 722: 721: 717: 714: 711: 708: 705: 702: 700: 696: 690: 686: 682: 678: 674: 670: 667: 665: 661: 657: 653: 649: 645: 641: 637: 633: 631: 628:after 3  627: 623: 619: 615: 611: 607: 605: 601: 597: 593: 591: 589: 588: 584: 583: 579: 576: 573: 570: 567: 565: 563: 562: 561:Latent period 558: 557: 554: 550: 546: 542: 539: 536: 533: 530: 527: 524: 521: 520: 516: 514:< 1 h 513: 511:< 1 h 510: 507: 504: 502: 501:Time of onset 499: 498: 494: 492:Severe (100%) 491: 488: 485: 482: 480: 477: 476: 472: 469: 466: 463: 460: 458: 457:Time of onset 455: 454: 450: 447: 444: 441: 438: 436: 433: 432: 428: 426:< 1 h 425: 422: 419: 416: 414: 413:Time of onset 411: 410: 407:Heavy (100%) 406: 403: 400: 397: 394: 392: 389: 388: 381: 378: 375: 372: 370: 367: 366: 362: 359: 356: 353: 350: 348: 347:Time of onset 345: 344: 340: 337: 334: 331: 328: 326: 322: 319: 317: 313: 310: 307:> 30  306: 304: 300: 298: 294: 292: 288: 286: 282: 281: 277: 273: 272:absorbed dose 262: 259: 252: 249: 246: 242: 239: 236: 233: 231: 227: 224: 221: 218: 215: 212: 211: 210: 206: 204: 200: 199:Deterministic 195: 188:Deterministic 185: 183: 178: 176: 172: 166: 164: 160: 156: 152: 147: 142: 140: 139:heart disease 136: 132: 131:teratogenesis 128: 124: 110: 107: 106: 105: 102: 100: 96: 86: 84: 80: 76: 72: 68: 67:latent period 64: 60: 56: 52: 48: 44: 40: 39:actinobiology 36: 32: 19: 4056:Radiobiology 4032:Radiobiology 3863:Survey meter 3783:Monitor unit 3729:Measurement 3720:Radiobiology 3719: 3626:Radiobiology 3508:Radiobiology 3507: 3468:Laser safety 3145: 3130:ICRP, 2007. 3112:the original 3083: 3079: 3066: 3054:. 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If this 123:stochastic 117:Stochastic 3976:NRC (USA) 3925:HPS (USA) 3826:Dosimeter 3743:Becquerel 3690:Dosimetry 3585:Half-life 3458:Dosimetry 3293:Gamma ray 3240:Microwave 3230:Starlight 3191:Radiation 2832:250827449 2703:1932-6203 2636:1759-4812 2561:ICRP 2007 2549:ICRP 2007 2537:ICRP 2007 2506:1465-542X 2413:0820-3946 2354:0820-3946 2216:ICRP 2007 2157:ICRP 2007 2129:Radiology 2084:microbeam 2080:electrons 2037:Neurology 1894:apoptosis 1876:Molecular 1690:cytotoxic 1678:lithium-7 1646:within a 1565:0.001 mSv 1551:0.005 mSv 1524:0.001 mSv 1498:6 months 1392:Abdominal 1345:6 months 1304:8 months 1279:Exam type 1217:exposure. 1115:(UNSCEAR) 988:dosimetry 947:IQ points 921:60 - 310 877:50 - 100 786:actinides 723:With care 699:Mortality 652:Dizziness 525:function 316:Immediate 295:6–8  289:2–6  283:1–2  251:Cataracts 3981:ONR (UK) 3971:IRR (UK) 3950:SRP (UK) 3889:Glovebox 3793:Roentgen 3235:Sunlight 3220:Infrared 3100:11572640 2876:(1955). 2762:11749482 2721:24915439 2673:PLOS ONE 2654:27578040 2524:15642178 2431:19047611 2372:19047611 2202:24275177 2098:See also 2017:Ontogeny 1848:and the 1682:helium-4 1672:. 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Index

Radiobiologist
medical sciences
ionizing radiation
radiation therapy
thyrotoxicosis
induction of cancer
latent period
radiation burns
acute radiation syndrome
medical imaging
radiotherapy
radiation therapy
thyrotoxicosis
stochastic
Radiation-induced cancer
teratogenesis
cognitive decline
heart disease
induction of cancer
effective radiation dose
sievert
linear model
background radiation
atomic bomb survivors
radioresistance
mSv
Acute radiation syndrome
Deterministic
threshold dose
Acute radiation syndrome

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