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Chemoprophylaxis

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lists the Malaria Consortium's SMC program as one of its priority programs due to its high level of cost-effectiveness and ability to absorbe additional funding.
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for anti-inflammatory therapy. Chemoprophylaxis is also used to treat several different varieties of meningococcal infections for close contact exposure to
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In some cases, chemoprophylaxis is initiated to prevent the spread of an existing infection in an individual to a new organ system, as when
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cancer, by ‘using physiological mechanisms that do not kill healthy cells. Anand Reddi proposed a role for the antidiabetes drug
195:, in which measures are undertaken to prevent the onset of disease in individuals who are susceptible (as when patients receive 165:, seeks to identify ‘agents to reverse, suppress or prevent the carcinogenic process,’ from premalignancy to invasive and or 127: 302: 236: 141:
recommends chemoprevention to prevent Malaria in the Sahel region of Sub-Saharan Africa through the use of the drugs
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The cost associated with chemoprophylaxis may be prohibitive, particularly when the cost of treatment is high or the
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Sporn, Michael B (July 1976). "Approaches to prevention of epithelial cancer during the preneoplastic period".
123: 379:"Therapeutic potential of the anti-diabetic agent metformin in targeting the skin cancer stem cell diaspora" 422: 98:. In general, chemoprophylaxis should be initiated only when the benefits of treatment outweigh the risks. 427: 322: 142: 138: 102: 204: 70: 62: 269: 131: 292: 226: 95: 90:
The use of chemoprophylaxis is limited primarily by two factors: risk and financial costs.
8: 432: 149:. This technique is called Seasonal Malaria Chemoprevention (SMC). The charity evaluator 65:). Antibiotics may also be administered to healthy individuals to limit the spread of an 378: 336: 192: 106: 398: 359: 298: 273: 232: 390: 265: 162: 105:
of the target disease is low. Many forms of chemoprophylaxis are therefore not
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Use of chemical compounds to prevent the development of a specific disease
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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy
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Woolf, Steven H.; Jonas, Steven; Kaplan-Liss, Evonne (2008),
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Using chemoprophylaxis as a treatment against early signs of
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Health Promotion and Disease Prevention in Clinical Practice
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Reddi, Anand; Powers, Matthew; Devalle, Robert (May 2014).
337:"Malaria Consortium – Seasonal Malaria Chemoprevention" 231:, Lippincott Williams & Wilkins, pp. 346–358, 69:, or to patients who have repeated infections (such as 254:"Health Span Extension through Green Chemoprevention" 224: 319:"WHO | Seasonal malaria chemoprevention (SMC)" 376: 297:, Lippincott Williams & Wilkins, p. 578, 161:Chemoprevention in cancer, was first proposed by 414: 252:Fahey, Jed W.; Kensler, Thomas W. (2013-04-01). 218: 251: 94:All medications have the potential to cause 126:physicians observed polyps regression with 270:10.1001/virtualmentor.2013.15.4.stas1-1304 284: 14: 415: 349: 290: 113: 24: 37:refers to the administration of a 25: 444: 83:is administered in patients with 173:as a chemoprevention agent for 122:has proven to be effective. In 370: 343: 329: 311: 245: 124:familial adenomatous polyposis 87:to prevent further infection. 57:function to prevent bacterial 41:for the purpose of preventing 13: 1: 211: 203:to delay the development of 7: 180: 10: 449: 156: 143:sulfadoxine/pyrimethamine 139:World Health Organization 383:Experimental Dermatology 291:Golan, David E. (2008), 71:urinary tract infections 205:coronary artery disease 63:opportunistic infection 189:, a more general term. 132:Neisseria meningitidis 258:AMA Journal of Ethics 423:Medical terminology 428:Medical treatments 193:Primary prevention 395:10.1111/exd.12349 114:Specific diseases 16:(Redirected from 440: 407: 406: 374: 368: 367: 347: 341: 340: 333: 327: 326: 321:. Archived from 315: 309: 308: 288: 282: 281: 249: 243: 242: 222: 35:chemoprophylaxis 21: 448: 447: 443: 442: 441: 439: 438: 437: 413: 412: 411: 410: 375: 371: 352:Cancer Research 348: 344: 335: 334: 330: 325:on May 3, 2014. 317: 316: 312: 305: 289: 285: 250: 246: 239: 223: 219: 214: 183: 159: 116: 31:Chemoprevention 28: 23: 22: 18:Chemoprevention 15: 12: 11: 5: 446: 436: 435: 430: 425: 409: 408: 369: 342: 328: 310: 304:978-0781783552 303: 283: 264:(4): 311–318. 244: 238:978-0781775991 237: 216: 215: 213: 210: 209: 208: 190: 182: 179: 158: 155: 115: 112: 111: 110: 107:cost-effective 99: 61:(particularly 26: 9: 6: 4: 3: 2: 445: 434: 431: 429: 426: 424: 421: 420: 418: 404: 400: 396: 392: 388: 384: 380: 373: 365: 361: 357: 353: 346: 338: 332: 324: 320: 314: 306: 300: 296: 295: 287: 279: 275: 271: 267: 263: 259: 255: 248: 240: 234: 230: 229: 221: 217: 206: 202: 198: 194: 191: 188: 185: 184: 178: 176: 172: 168: 164: 163:Michael Sporn 154: 152: 148: 144: 140: 135: 133: 129: 125: 121: 108: 104: 100: 97: 93: 92: 91: 88: 86: 82: 79: 74: 72: 68: 64: 60: 56: 55:immune system 52: 48: 44: 40: 36: 32: 19: 386: 382: 372: 358:: 2699-702. 355: 351: 345: 331: 323:the original 313: 293: 286: 261: 257: 247: 227: 220: 160: 136: 120:tuberculosis 117: 96:side effects 89: 81:chemotherapy 75: 34: 30: 29: 187:Prophylaxis 175:skin cancer 147:amodiaquine 78:intrathecal 51:Antibiotics 433:Prevention 417:Categories 212:References 167:metastatic 85:malignancy 59:infections 39:medication 278:2376-6980 171:metformin 103:incidence 47:infection 403:24521225 181:See also 151:GiveWell 67:epidemic 364:1277177 201:statins 197:aspirin 43:disease 401:  362:  301:  276:  235:  157:Cancer 128:NSAIDs 389:(5). 399:PMID 360:PMID 299:ISBN 274:ISSN 233:ISBN 145:and 137:The 391:doi 266:doi 199:or 49:. 45:or 33:or 419:: 397:. 387:23 385:. 381:. 356:36 354:. 272:. 262:15 260:. 256:. 207:). 177:. 134:. 405:. 393:: 366:. 339:. 307:. 280:. 268:: 241:. 109:. 20:)

Index

Chemoprevention
medication
disease
infection
Antibiotics
immune system
infections
opportunistic infection
epidemic
urinary tract infections
intrathecal
chemotherapy
malignancy
side effects
incidence
cost-effective
tuberculosis
familial adenomatous polyposis
NSAIDs
Neisseria meningitidis
World Health Organization
sulfadoxine/pyrimethamine
amodiaquine
GiveWell
Michael Sporn
metastatic
metformin
skin cancer
Prophylaxis
Primary prevention

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