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Mouth ulcer

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major and herpetiform major aphthous ulceration. Minor aphthous ulceration is the most common type, presenting with 1–6 small (2-4mm diameter), round/oval ulcers with a yellow-grey color and an erythematous (red) "halo". These ulcers heal with no permanent scarring in about 7–10 days. Ulcers recur at intervals of about 1–4 months. Major aphthous ulceration is less common than the minor type, but produces more severe lesions and symptoms. Major aphthous ulceration presents with larger (>1 cm diameter) ulcers that take much longer to heal (10–40 days) and may leave scarring. The minor and major subtypes of aphthous stomatitis usually produce lesions on the non-keratinized oral mucosa (i.e. the inside of the cheeks, lips, underneath the tongue and the
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very unlikely to be oral cancer. The size of the ulcers may be helpful in distinguishing the types of RAS, as can the location (minor RAS mainly occurs on non-keratinizing mucosa, major RAS occurs anywhere in the mouth or oropharynx). Induration, contact bleeding and rolled margins are features of a malignant ulcer. There may be nearby causative factor, e.g. a broken tooth with a sharp edge that is traumatizing the tissues. Otherwise, the person may be asked about problems elsewhere, e.g. ulceration of the genital mucous membranes, eye lesions or digestive problems, swollen glands in neck (
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internally, and this has led to a rise in the frequency of intra-oral thermal burns. Thermal food burns are usually on the palate or posterior buccal mucosa, and appear as zones of erythema and ulceration with necrotic epithelium peripherally. Electrical burns more commonly affect the oral commissure (corner of the mouth). The lesions are usually initially painless, charred and yellow with little bleeding. Swelling then develops and by the fourth day following the burn the area becomes necrotic and the epithelium sloughs off.
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only nonspecific lesions in the mouth. The vesicles and bullae of blistering mucocutaneous disorders progress quickly to ulceration in the mouth, because of moisture and trauma from food and teeth. The high bacterial load in the mouth means that ulcers may become secondarily infected. Cytotoxic drugs administered during chemotherapy target cells with fast turnovers such as malignant cells. However, the epithelia of the mouth also has a high turnover rate and makes oral ulceration (
2746: 60: 1150: 230: 417:(white, thickened mucosa) margin. Malignant lesions may ulcerate either because the tumor infiltrates the mucosa from adjacent tissues, or because the lesion originates within the mucosa itself, and the disorganized growth leads to a break in the normal architecture of the lining tissues. Repeat episodes of mouth ulcers can be indicative of an 1235:(hardened) and attached to adjacent structures, with "rolled" margins or a punched out appearance and bleeds easily on gentle manipulation. If someone has an unexplained mouth ulcer persisting for more than 3 weeks this may indicate a need for a referral from the GDP or GP to hospital to exclude oral cancer. 787:. Herpetiform ulcers begin as small blisters (vesicles) which break down into 2-3mm sized ulcers. Herpetiform ulcers appear in "crops" sometimes hundreds in number, which can coalesce to form larger areas of ulceration. This subtype may cause extreme pain, heals with scarring and may recur frequently. 481:
Diagnosis of mouth ulcers usually consists of a medical history followed by an oral examination as well as examination of any other involved area. The following details may be pertinent: The duration that the lesion has been present, the location, the number of ulcers, the size, the color and whether
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Caustic chemicals may cause ulceration of the oral mucosa if they are of strong-enough concentration and in contact for a sufficient length of time. The holding of medication in the mouth instead of swallowing it occurs mostly in children, those under psychiatric care, or simply because of a lack of
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may be required, to rule out cancer, but also if a systemic disease is suspected. Ulcers caused by local trauma are painful to touch and sore. They usually have an irregular border with erythematous margins and the base is yellow. As healing progresses, a keratotic (thickened, white mucosa) halo may
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Common sites of oral cancer are the lower lip, the floor of the mouth, and the sides, underside of the tongue and mandibular alveolar ridge, but it is possible to have a tumor anywhere in the mouth. Appearances vary greatly, but a typical malignant ulcer would be a persistent, expanding lesion that
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Aphthous stomatitis (also termed recurrent aphthous stomatitis, RAS, and commonly called "canker sores") is a very common cause of oral ulceration. 10–25% of the general population have this non-contagious condition. Three types of aphthous stomatitis exists based on their appearance, namely minor,
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An ulcer that keeps forming on the same site and then healing may be caused by a nearby sharp surface, and ulcers that heal and then recur at different sites are likely to be recurrent aphthous stomatitis (RAS). Malignant ulcers are likely to be single in number, and conversely, multiple ulcers are
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Similarly, cutaneous (skin) conditions can also involve the mouth and sometimes only the mouth, sparing the skin. The different environmental conditions (saliva, thinner mucosa, trauma from teeth and food) mean that some cutaneous disorders which produce characteristic lesions on the skin produce
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Thermal burns usually result from placing hot food or beverages in the mouth. This may occur in those who eat or drink before a local anesthetic has worn off. The normal painful sensation is absent and a burn may occur. Microwave ovens sometimes produce food that is cold externally and very hot
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Electrical burns in the mouth are usually caused by chewing on live electrical wiring (an act that is relatively common among young children). Saliva acts as a conducting medium and an electrical arc flows between the electrical source and the tissues, causing extreme heat and possible tissue
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Pathologically, the mouth represents a transition between the gastrointestinal tract and the skin, meaning that many gastrointestinal and cutaneous conditions can involve the mouth. Some conditions usually associated with the whole gastrointestinal tract may present only in the mouth, e.g.,
213:("canker sores"), a condition characterized by the recurrent formation of oral ulcers for largely unknown reasons. Mouth ulcers often cause pain and discomfort and may alter the person's choice of food while healing occurs (e.g. avoiding acidic, sugary, salty or spicy foods and beverages). 744:, and causes chronic pain and surface ulceration, sometimes resulting in non-healing bone being exposed through a soft tissue defect. Prevention of osteradionecrosis is part of the reason why all teeth of questionable prognosis are removed before the start of a course of radiotherapy. 699:
is used during dental treatment as a cavity sterilizing agent and cauterizing material, and it is also present in some over-the-counter agents intended to treat aphthous ulcerations. Mucosal necrosis has been reported to occur with concentrations of 0.5%. Other materials used in
578: 826:). Aphthous stomatitis has no clinically detectable signs or symptoms outside the mouth, but the recurrent ulceration can cause much discomfort to those affected. Treatment is aimed at reducing the pain and swelling and speeding healing, and may involve systemic or topical 160:
developing in those who use prolonged steroids; people with mouth ulcers may prefer to avoid hot or spicy foods, which can increase the pain; self-inflicted ulceration can be difficult to manage, and psychiatric input may be required in some people; for recurrent ulcers,
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and takes on a yellow-grey color. Because an ulcer is a breach of the normal lining, when seen in cross section, the lesion is a crater. A "halo" may be present, which is a reddening of the surrounding mucosa and is caused by inflammation. There may also be
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The diagnosis comes mostly from the history and examination, but the following special investigations may be involved: blood tests (vitamin deficiency, anemia, leukemia, Epstein-Barr virus, HIV infection, diabetes) microbiological swabs (infection), or
152:; A topical analgesic (e.g. benzydamine mouthwash) to reduce pain Topical (gels, creams or inhalers) or systemic steroids may be used to reduce inflammation; Topical (gels, creams or inhalers) or systemic steroids may be used to reduce inflammation; an 107:); injuries (e.g. biting of the lip, tongue, and cheek, hard foods can scrape the oral tissues, hot foods can cause burns); Nutritional disorders (e.g., vitamin deficiencies); Possibly heavy metals, of which cadmium occurs in phosphate rock; 1547:
Oral ulceration is a common reason for people to seek medical or dental advice. A breach of the oral mucosa probably affects most people at various times during life. For a discussion of the epidemiology of aphthous stomatitis, see
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describes a common vascular anomaly where a main arterial branch extends into superficial submucosal tissues without a reduction of diameter. This commonly occurs in elderly people on the lip and may be associated with ulceration.
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Erosions, which involve the epithelial layer, are red in appearance since the underlying lamina propria shows through. When the full thickness of the epithelium is penetrated (ulceration), the lesion becomes covered with a
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it is hard to touch, bleeds or has a rolled edge. As a general rule, a mouth ulcer that does not heal within 2 or 3 weeks should be examined by a health care professional who is able to rule out oral cancer (e.g. a
202:. Mouth ulcers are very common, occurring in association with many diseases and by many different mechanisms, but usually there is no serious underlying cause. Rarely, a mouth ulcer that does not heal may be a sign of 1070: 2664: 2649: 2634: 783:), but less commonly major aphthous ulcers may occur in other parts of the mouth on keratinized mucosal surfaces. The least common type is herpetiform ulceration, so named because the condition resembles 569:
are caused by local trauma. The mucous membrane lining of the mouth is thinner than the skin, and easily damaged by mechanical, thermal (heat/cold), chemical, or electrical means, or by irradiation.
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Eating hard foods (e.g., potato chips) can damage the lining of the mouth. Some people cause damage inside their mouths themselves, either through an absentminded habit or as a type of deliberate
1314:, or angles of their mouth). Balsam of Peru is used in foods and drinks for flavoring, in perfumes and toiletries for fragrance, and in medicine and pharmaceutical items for healing properties. 736:
and impairs the blood supply. The affected hard tissues become hypovascular (reduced number of blood vessels), hypocellular (reduced number of cells), and hypoxic (low levels of oxygen).
206:. These ulcers may form individually or multiple ulcers may appear at once (i.e., a "crop" of ulcers). Once formed, an ulcer may be maintained by inflammation and/or secondary infection. 103:(a common ingredient in many toothpastes) have been linked to mouth ulcers, and have been recognized by public health agencies such as the NHS as a risk factor.; infections (e.g. 753: 1476:
if the underlying cause is unknown or not correctable. It is also important to note that most ulcers will heal completely without any intervention. Treatment can range from:
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ulceration). Examples include biting the cheek, tongue, or lips, or rubbing a fingernail, pen, or toothpick inside the mouth. Tearing (and subsequent ulceration) of the
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is a term sometimes used to describe a breach of the epithelium which is deeper than an erosion but shallower than an ulcer. This type of lesion is tangential to the
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Rarely, allergic reactions of the mouth and lips may manifest as erosions; however, such reactions usually do not produce frank ulceration. An example of one common
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Mouth ulcers may be caused by physical means (for example accidental biting of the cheek), certain medical conditions (such as some vitamin deficiencies), or as an
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The two most common causes of oral ulceration are local trauma (e.g. rubbing from a sharp edge on a broken filling or braces, biting one's lip, etc.) and
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which impairs wound healing, which can contribute to ulcer formation. For a detailed discussion of the pathophysiology of aphthous stomatitis, see
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The exact cause of aphthous stomatitis is unknown, but there may be a genetic predisposition in some people. Other possible causes include
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Aphthous stomatitis and local trauma are very common causes of oral ulceration; the many other possible causes are all rare in comparison.
369:(dry mouth – as saliva usually lubricates the mucous membrane and controls bacterial levels) and epithelial atrophy (thinning, e.g., after 2247:
Kharazmi M, Sjöqvist K, Warfvinge G (April 2012). "Oral ulcers, a little known adverse effect of alendronate: review of the literature".
728:(dry mouth), making the oral mucosa more vulnerable to frictional damage as the lubricating function of saliva is lost, and mucosal 724:
may develop, which can be associated with mucosal erosions and ulceration. If the salivary glands are irradiated, there may also be
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Common causes of oral ulceration include rubbing on sharp edges of teeth, fillings, crowns, false teeth (dentures), or braces (
2576:"Effectiveness of Vitamin B12 in Treating Recurrent Aphthous Stomatitis: A Randomized, Double-Blind, Placebo-Controlled Trial" 297:. An ulcer is a deeper breach of epithelium compared to an erosion or excoriation, and involves damage to both epithelium and 2375: 2096: 1952: 1902: 1824: 1777: 1731: 1675: 1446: 2756: 3771: 2470: 1118: 2204:
Rezk SA, Zhao X, Weiss LM (September 2018). "Epstein-Barr virus (EBV)-associated lymphoid proliferations, a 2018 update".
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and others may also be possible. Either the tumor arises in the mouth, or it may grow to involve the mouth, e.g. from the
453:/ulceration of the oral mucosa. Numerous aphthous ulcers could be indicative of an inflammatory autoimmune disease called 4443: 4286: 3560: 3044: 2517: 2425: 966: 784: 148:
Smoothing or removing a local cause of trauma; addressing dry mouth; substituting a problem medication or switching to
4687: 3320: 2551: 2480: 1459:, an abnormally large tongue, can be associated with ulceration if the tongue protrudes constantly from the mouth. 732:(thinning), which makes a breach of the epithelium more likely. Radiation to the bones of the jaws causes damage to 100: 4662: 4599: 4594: 4476: 3904: 3884: 2796: 1415: 270:, "ulcer, sore") is a break in the skin or mucous membrane with loss of surface tissue and the disintegration and 4790: 4508: 4145: 3599: 1487: 740:
is the term for when such an area of irradiated bone does not heal from this damage. This usually occurs in the
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are all causes of immunodeficiency/immunosuppression with which oral ulcers may become a common manifestation.
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is an erosion which specifically occurs on a mucous membrane. Only the superficial epithelial cells of the
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Self-inflicted ulceration can be difficult to manage, and psychiatric input may be required in some people
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Opportunistic activity by combinations of otherwise normal bacterial flora, such as aerobic streptococci,
4385: 4348: 4078: 3359: 3271: 1450: 306: 4395: 4343: 4150: 4083: 3852: 3352: 3347: 3298: 1339: 1258: 995: 691:, used to treat gum disease, is also capable of causing epithelial necrosis at concentrations of 1–3%. 593:), or accidental biting caused by a lack of awareness of painful stimuli in the mouth (e.g., following 518:(minor procedure to cut out a small sample of the ulcer to look at under a microscope) with or without 442: 17: 1549: 377:
is a general term meaning inflammation within the mouth, and often may be associated with ulceration.
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Due to various factors (saliva, relative thinness of oromucosa, trauma from teeth, chewing, etc.),
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Diagramatic representation of mucosal erosion (left), excoriation (center), and ulceration (right)
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Li, J; Zhang, YY; Wang, NN; Bhandari, R; Liu, QQ (April 2016). "Riga-Fede disease in a child".
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used during dental treatment, which the person becomes aware of as the anesthetic wears off).
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People with mouth ulcers may prefer to avoid hot or spicy foods, which can increase the pain
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Topical (gels, creams or inhalers) or systemic steroids may be used to reduce inflammation
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Volkov, I.; Rudoy, I.; Freud, T.; Sardal, G.; Naimer, S.; Peleg, R.; Press, Y. (2009).
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to the soft tissues of the mouth are common. Some dentists apply a protective layer of
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Toon MH, Maybauer DM, Arceneaux LL, Fraser JF, Meyer W, Runge A, Maybauer MO (2011).
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Loevy, Manfred Strassburg, Gerdt Knolle; translated by Hannelore Taschini (1993).
4579: 4365: 4160: 4053: 3889: 3808: 3788: 3712: 3697: 3567: 3471: 3439: 3410: 3332: 3258: 3054: 2937: 2927: 2872: 2857: 2684: 2592: 2575: 1862: 1845: 1196: 1134: 1082: 962: 624: 536: 503: 195: 642:"). Rarely, infants can ulcerate the tongue or lower lip with the teeth, termed 310:
is a superficial breach of the epithelium, with little damage to the underlying
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Tyldesley, Anne Field, Lesley Longman in collaboration with William R. (2003).
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Iatrogenic ulceration can also occur during dental treatment, where incidental
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Oral and maxillofacial medicine : the basis of diagnosis and treatment
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Many infections can cause oral ulceration (see table). The most common are
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Simple mechanisms which predispose the mouth to trauma and ulceration are
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Fazzi M, Vescovi P, Savi A, Manfredi M, Peracchia M (October 1999). "".
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Many drugs can cause mouth ulcers as a side effect. Common examples are
413:(swelling) around the ulcer. Chronic trauma may produce an ulcer with a 4652: 4438: 4264: 4032: 3862: 3803: 3741: 3731: 3724: 3719: 3657: 3640: 3584: 3555: 3476: 3337: 3315: 3200: 3180: 1934: 1497: 1355: 1300: 1232: 1122: 877: 869: 835: 823: 725: 721: 705: 511: 374: 366: 338:
and shows punctiform (small pinhead spots) bleeding, caused by exposed
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or of the mucosa are lost, and the lesion can reach the depth of the
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Some of the viral infections mentioned above are also classified as
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species can prolong the ulcerative process. Fungal causes include
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Sapp, J. Phillip; Lewis Roy Eversole; George W. Wysocki (2004).
1065:, is sometimes known to cause mouth ulcers through formation of 285:
An ulcer is a tissue defect which has penetrated the epithelial-
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to the lips before carrying out dental work to minimize this.
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periodic fever, aphthous stomatitis, pharyngitis and adenitis
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change. The patient died two months after subsequent partial
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is also vulnerable to ulceration by repeated friction during
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Scully, Crispian (2008). "Chapter 14: Soreness and ulcers".
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is an ulcer which specifically occurs on a mucous membrane.
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Simplistic representation of the life cycle of mouth ulcers.
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are also caustic, which is part of the reason why use of a
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tend to be fragile and quickly break down to leave ulcers.
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or peri-oral skin. The most common type of oral cancer is
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Epstein-Barr virus-associated lymphoproliferative diseases
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tablet next to a painful tooth in an attempt to relieve
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Cawson's essentials of oral pathology and oral medicine
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A wide range of other diseases may cause mouth ulcers.
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Rarely, a persistent, non-healing mouth ulcer may be a
373:), making the lining more fragile and easily breached. 2573: 2418:
Oral pathology : clinical pathologic correlations
1137:). Some recreational drugs can cause ulceration, e.g. 30:"Cancer sore" redirects here. Not to be confused with 2358:
James R. Hupp; Myron R. Tucker; Edward Ellis (2008).
2351: 2087:(2. ed.). Philadelphia: W.B. Saunders. pp.  1893:(10th ed.). Hamilton, Ont.: BC Decker. pp.  1307:(inflammation, rash, or painful erosion of the lips, 252: 2795: 2616: 2580:
The Journal of the American Board of Family Medicine
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Gottfried Schmalz; Dorthe Arenholt Bindslev (2008).
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The exact pathogenesis is dependent upon the cause.
249: 2420:(6th ed.). St. Louis, Mo.: Elsevier/Saunders. 2415: 2111: 243: 4209:Jaw joints, chewing muscles and bite abnormalities 2079:BW Neville; DD Damm; CM Allen; JE Bouquot (2002). 1936: 1878: 1486:Substituting a problem medication or switching to 3072: 2059: 1925: 1668:Diseases of the Oral Mucosa : A Colour Atlas 1253:. Other example vesiculobullous diseases include 4777: 3409: 1889:Burket's oral medicine diagnosis & treatment 4564:Teeth, jaws, tongue and associated soft tissues 2505: 2284:"Persistent nicorandil induced oral ulceration" 2281: 1071:Epstein-Barr virus-positive mucocutaneous ulcer 565:Most mouth ulcers that are not associated with 3176:Hereditary benign intraepithelial dyskeratosis 1525:developing in those who use prolonged steroids 1183:lesion. Malignancies in the mouth are usually 842:or barrier pastes to protect the raw area(s). 649: 27:Sore on the mucous membrane of the oral cavity 4134:Neuralgia-inducing cavitational osteonecrosis 2781: 2439: 2437: 2240: 2203: 1939:Contemporary Oral and Maxillofacial Pathology 1638:"Ulcer on Merriam-Webster medical dictionary" 1581: 1579: 1577: 1480:Smoothing or removing a local cause of trauma 1287:Stomatitis § Allergic contact stomatitis 1219:consumption (particularly when combined) and 289:border, with its base at a deep level in the 111:is commonly associated with recurrent ulcers. 2197: 1967: 1917:: CS1 maint: multiple names: authors list ( 1885:Glick, Martin S. Greenberg, Michael (2003). 1792:: CS1 maint: multiple names: authors list ( 1690:: CS1 maint: multiple names: authors list ( 1661: 1659: 1657: 1655: 67:A mouth ulcer (in this case associated with 2543:Conn's Current Therapy 2014: Expert Consult 2392:"BNF and BNFc are only available in the UK" 2362:Contemporary oral and maxillofacial surgery 2010: 1961: 1238: 445:, an autoimmune reaction to the epithelial 2788: 2774: 2540:Edward T. Bope; Rick D. Kellerman (2013). 2501: 2499: 2464: 2462: 2434: 2409: 2275: 1574: 457:. This can later involve skin lesions and 58: 2591: 2416:Regezi JA, Sciubba JJ, Jordan RK (2011). 2307: 2282:Healy CM, Smyth Y, Flint SR (July 2004). 2249:Journal of Oral and Maxillofacial Surgery 2180: 2042: 2016: 1993: 1861: 1767: 1652: 558:A "crop" of trauma-induced ulcers on the 526: 4786:Herpes simplex virus–associated diseases 1844:, Beer-Gabel M, Eliakim R (March 2012). 1833: 1585: 1148: 751: 576: 553: 397:) a common side effect of chemotherapy. 326:. Erosions heal without scar formation. 228: 220: 4761:Oral manifestations of systemic disease 3910:Acute necrotizing ulcerative gingivitis 2496: 2459: 2161:Journal of Injury and Violence Research 1550:the epidemiology of aphthous stomatitis 902:acute necrotizing ulcerative gingivitis 549: 14: 4778: 3947:As a manifestation of systemic disease 1807:RA Cawson; EW Odell; S Porter (2002). 1721: 1211:. The main risk factors are long-term 747: 4734: 4633: 4557: 4315: 4194: 3980: 3770: 3408: 3071: 3011: 2899: 2807: 2769: 2114:Clinical and Experimental Dermatology 1884: 1665: 1472:Treatment is cause-related, but also 1119:non-steroidal anti-inflammatory drugs 851:Infectious causes of oral ulceration 3793:Gums and tooth-supporting structures 2472:Biocompatibility of Dental Materials 2148: 2023:Clinical and Experimental Immunology 441:is also a cause of oral ulceration. 4444:Papillary cystadenoma lymphomatosum 4316: 4287:Temporomandibular joint dysfunction 1968:Scully C, Shotts R (15 July 2000). 24: 3561:Maxillary lateral incisor agenesis 3045:Inflammatory papillary hyperplasia 2083:Oral & maxillofacial pathology 967:primary herpetic gingivostomatitis 785:primary herpetic gingivostomatitis 679:Other caustic medications include 662: 357: 25: 4802: 2612: 2447:. Dermnetnz.org. 28 December 2013 4663:Cutaneous sinus of dental origin 4600:Obesity hypoventilation syndrome 4595:Central hypoventilation syndrome 4477:Carcinoma ex pleomorphic adenoma 3905:Necrotizing periodontal diseases 3885:Hereditary gingival fibromatosis 2797:Oral and maxillofacial pathology 2744: 2445:"Balsam of Peru contact allergy" 2035:10.1111/j.1365-2249.2008.03857.x 1850:Journal of Crohn's & Colitis 1453:may present as oral ulceration. 1416:granulomatosis with polyangiitis 720:to the mouth, radiation-induced 506:) or a general unwell feeling. 239: 165:has been shown to be effective; 4509:Chronic sclerosing sialadenitis 4146:Osteoporotic bone marrow defect 3600:Keratocystic odontogenic tumour 2567: 2533: 2384: 2324: 2105: 1542: 1317: 1169:(removal of part of the tongue) 1088: 4494:Sclerosing polycystic adenosis 4329:Benign lymphoepithelial lesion 2749:Learning materials related to 1740: 1630: 1602: 1538:has been shown to be effective 711: 425:in the oral mucous membranes. 13: 1: 4688:Melkersson–Rosenthal syndrome 4637:Soft tissues around the mouth 4334:Ectopic salivary gland tissue 2218:10.1016/j.humpath.2018.05.020 1588:"Mouth ulcers on MedlinePlus" 1567: 1384:chronic ulcerative stomatitis 1144: 572: 567:recurrent aphthous stomatitis 216: 3858:Gingival cyst of the newborn 3467:Failure of eruption of teeth 3171:Hand, foot and mouth disease 3156:Focal epithelial hyperplasia 3094:Angina bullosa haemorrhagica 3040:Palatal cysts of the newborn 2963:Transient lingual papillitis 2593:10.3122/jabfm.2009.01.080113 2546:. Elsevier Health Sciences. 2512:. Elsevier Health Sciences. 1863:10.1016/j.crohns.2011.07.001 1521:drug may be used to prevent 1467: 1392:angina bullosa haemorrhagica 1390:(Stevens-Johnson syndrome), 991:Human immunodeficiency virus 987:hand, foot and mouth disease 886:human immunodeficiency virus 874:hand, foot and mouth disease 845: 476: 156:drug may be used to prevent 7: 4386:Salivary gland diverticulum 4349:Necrotizing sialometaplasia 3360:Smokeless tobacco keratosis 3272:Basaloid squamous carcinoma 1974:BMJ (Clinical Research Ed.) 1555: 1451:necrotizing sialometaplasia 650:Thermal and electrical burn 293:, or even within muscle or 10: 4807: 4396:Salivary gland hyperplasia 4344:HIV salivary gland disease 3853:Gingival cyst of the adult 3299:Oral florid papillomatosis 3012: 2900: 2261:10.1016/j.joms.2011.03.046 1507:A topical analgesic (e.g. 1340:hypereosinophilic syndrome 1284: 1280: 1259:mucous membrane pemphigoid 1242: 1172: 1101:, commonly prescribed for 996:Mycobacterium tuberculosis 771: 768:"halo" surrounding lesion) 668:understanding. Holding an 471:Aphthous stomatitis#Causes 443:Mucous membrane pemphigoid 421:, signaling low levels of 29: 4741: 4735: 4730: 4643: 4635:Orofacial soft tissues – 4629: 4570: 4553: 4401:Salivary gland hypoplasia 4324: 4311: 4215: 4190: 4129:Bisphosphonate-associated 4023:Idiopathic osteosclerosis 3998: 3976: 3799: 3766: 3494:Dentinogenesis imperfecta 3430: 3404: 3084: 3067: 3020: 3007: 2958:Median rhomboid glossitis 2908: 2895: 2816: 2803: 2716: 2620: 1770:Tyldesley's Oral medicine 1615:Dictionary.com Unabridged 1511:mouthwash) to reduce pain 1500:mouthwash or spray (e.g. 1461:Caliber persistent artery 1348:myelodysplastic syndromes 822:(found in many brands of 616:(non-accidental injury). 345: 144: 115: 95: 79: 75:(lining of the lower lip) 66: 57: 53:Oral ulcer, mucosal ulcer 49: 44: 4708:Orofacial granulomatosis 4487:Mucoepidermoid carcinoma 4472:Adenoid cystic carcinoma 4406:Salivary gland neoplasms 4197:Temporomandibular joints 4168:Periapical periodontitis 3900:Linear gingival erythema 3668:Regional odontodysplasia 3514:Enamel hypocalcification 2808: 2506:Thomas P. Habif (2009). 2017:Keogan MT (April 2009). 1986:10.1136/bmj.321.7254.162 1372:orofacial granulomatosis 1267:dermatitis herpetiformis 1251:vesiculobullous diseases 1239:Vesiculobullous diseases 1047:Blastomyces dermatitidis 890:infectious mononucleosis 383:orofacial granulomatosis 186:), or sometime called a 4605:Obstructive sleep apnea 4371:Salivary duct stricture 4151:Paget's disease of bone 3648:Pulp canal obliteration 3489:Dentin hypersensitivity 3435:Amelogenesis imperfecta 3287:Squamous cell carcinoma 3267:Adenosquamous carcinoma 3254:Squamous cell papilloma 3231:Melanocytic oral lesion 2300:10.1136/hrt.2003.031831 1245:Vesiculobullous disease 1209:squamous cell carcinoma 1125:(may be prescribed for 1077:in which infiltrating, 1038:Cryptococcus neoformans 818:or hypersensitivity to 585:on the lower inside lip 465:deficiency may lead to 135:Vesiculobullous disease 4791:Oral mucosal pathology 4751:Hemifacial hypertrophy 4718:Pyostomatitis vegetans 4391:Salivary gland fistula 4381:Salivary gland atresia 4376:Salivary gland aplasia 4230:Mandibular dislocation 4201:muscles of mastication 4079:Calcifying odontogenic 3708:Vertical root fracture 3703:Cracked tooth syndrome 3678:Shovel-shaped incisors 3573:Wisdom tooth impaction 3455:Early childhood caries 3321:Benign mucous membrane 3282:Spindle cell carcinoma 3191:Intraoral dental sinus 3109:Burning mouth syndrome 1640:. Merriam-Webster, Inc 1562:Sodium dodecyl sulfate 1534:For recurrent ulcers, 1170: 1073:is a rare form of the 938:paracoccidioidomycosis 820:sodium lauryl sulphate 769: 591:orthodontic appliances 586: 562: 527:Differential diagnosis 234: 226: 121:Traumatic ulceration; 4560:Stomatognathic system 4462:Acinic cell carcinoma 4084:Glandular odontogenic 3236:Molluscum contagiosum 2333:Minerva Stomatologica 1750:. NHS. 11 March 2024. 1586:Vorvick LJ, Zieve D. 1275:epidermolysis bullosa 1152: 1056:Entamoeba histolytica 906:gangrenous stomatitis 806:), stopping smoking, 755: 581:A small ulcer on the 580: 557: 496:maxillofacial surgeon 354:of some medications. 232: 224: 4703:Oral Crohn's disease 4658:Basal cell carcinoma 4297:Condylar hyperplasia 4282:Maxillary hypoplasia 3848:Gingival enlargement 3781:periodontal ligament 3387:Verruciform xanthoma 3119:Condyloma acuminatum 2509:Clinical Dermatology 2173:10.5249/jivr.v3i2.91 1483:Addressing dry mouth 1424:giant cell arteritis 1420:periarteritis nodosa 1030:Coccidioides immitis 708:is now recommended. 636:oral sexual activity 550:Traumatic ulceration 4713:Perioral dermatitis 4449:Pleomorphic adenoma 4429:Monomorphic adenoma 4419:Canalicular adenoma 4292:Condylar hypoplasia 4225:Condylar resorption 4069:Lateral periodontal 4028:Mandibular fracture 3927:Periodontal abscess 3524:Turner's hypoplasia 3292:Verrucous carcinoma 3241:Morsicatio buccarum 3221:Lupus erythematosus 3134:Erythema multiforme 3050:Stomatitis nicotina 1488:SLS-free toothpaste 1400:lupus erythematosus 1388:erythema multiforme 1350:, other white cell 1024:, spirochetes, and 882:herpetic stomatitis 852: 840:anti-inflammatories 774:Aphthous stomatitis 748:Aphthous stomatitis 610:upper labial frenum 533:vesicles and bullae 211:aphthous stomatitis 194:that occurs on the 150:SLS-free toothpaste 123:Aphthous stomatitis 69:aphthous stomatitis 4756:Facial hemiatrophy 4610:Periodic breathing 4541:Sjögren's syndrome 4414:Basal cell adenoma 4178:Torus mandibularis 4156:Periapical abscess 4139:Osteoradionecrosis 4064:Buccal bifurcation 4043:Intraosseous cysts 3932:Periodontal trauma 3836:Pyogenic granuloma 3683:Supernumerary root 3636:Pulp calcification 3624:Premature eruption 3595:Odontogenic tumors 3392:White sponge nevus 3365:Submucous fibrosis 3309:Smoker's melanosis 3196:Irritation fibroma 3035:High-arched palate 2943:Foliate papillitis 2933:Cunnilingus tongue 2918:Black hairy tongue 2848:Congenital lip pit 2717:External resources 1447:eosinophilic ulcer 1408:reactive arthritis 1376:ulcerative colitis 1271:linear IgA disease 1263:bullous pemphigoid 1255:pemphigus vulgaris 1171: 1079:Epstein-Barr virus 1006:Treponema pallidum 850: 770: 738:Osteoradionecrosis 640:cunnilingus tongue 587: 563: 535:which form on the 520:immunofluorescence 235: 227: 99:Chemicals such as 4773: 4772: 4769: 4768: 4726: 4725: 4625: 4624: 4549: 4548: 4454:Sebaceous adenoma 4307: 4306: 4186: 4185: 4097:Median mandibular 4092:Nasopalatine duct 4008:Alveolar osteitis 3972: 3971: 3959:Perio-endo lesion 3841:Congenital epulis 3762: 3761: 3519:Enamel hypoplasia 3400: 3399: 3375:Riga–Fede disease 3226:Melanocytic nevus 3166:Hairy leukoplakia 3129:Epulis fissuratum 3063: 3062: 3003: 3002: 2953:Geographic tongue 2891: 2890: 2740: 2739: 2377:978-0-323-04903-0 2126:10.1111/ced.12728 2098:978-0-7216-9003-2 1954:978-0-323-01723-7 1904:978-1-55009-186-1 1826:978-0-443-07106-5 1779:978-0-19-263147-3 1733:978-0-443-06818-8 1677:978-0-86715-210-4 1492:Maintaining good 1050:("North American 983:coxsackie A virus 955: 954: 689:Hydrogen peroxide 644:Riga-Fede disease 612:may be a sign of 447:basement membrane 324:basement membrane 287:connective tissue 276:epithelial tissue 176: 175: 117:Diagnostic method 39:Medical condition 16:(Redirected from 4798: 4732: 4731: 4631: 4630: 4555: 4554: 4424:Ductal papilloma 4313: 4312: 4192: 4191: 4089:Non-odontogenic: 4074:Globulomaxillary 4013:Buccal exostosis 3978: 3977: 3922:Peri-implantitis 3768: 3767: 3484:Dentin dysplasia 3406: 3405: 3382:Verruca vulgaris 3277:Mucosal melanoma 3124:Darier's disease 3099:Behçet's disease 3069: 3068: 3025:Bednar's aphthae 3009: 3008: 2897: 2896: 2883:Trumpeter's wart 2805: 2804: 2790: 2783: 2776: 2767: 2766: 2748: 2618: 2617: 2606: 2605: 2595: 2571: 2565: 2564: 2562: 2560: 2537: 2531: 2530: 2528: 2526: 2503: 2494: 2493: 2491: 2489: 2466: 2457: 2456: 2454: 2452: 2441: 2432: 2431: 2413: 2407: 2406: 2404: 2402: 2388: 2382: 2381: 2365: 2355: 2349: 2348: 2328: 2322: 2321: 2311: 2279: 2273: 2272: 2244: 2238: 2237: 2201: 2195: 2194: 2184: 2152: 2146: 2145: 2109: 2103: 2102: 2086: 2076: 2057: 2056: 2046: 2014: 2008: 2007: 1997: 1980:(7254): 162–65. 1965: 1959: 1958: 1942: 1932: 1923: 1922: 1916: 1908: 1892: 1882: 1876: 1875: 1865: 1837: 1831: 1830: 1814: 1804: 1798: 1797: 1791: 1783: 1765: 1752: 1751: 1744: 1738: 1737: 1719: 1696: 1695: 1689: 1681: 1663: 1650: 1649: 1647: 1645: 1634: 1628: 1627: 1625: 1623: 1606: 1600: 1599: 1597: 1595: 1583: 1523:oral candidiasis 1360:Gastrointestinal 1227:is totally red ( 1131:propylthiouracil 1083:mucous membranes 971:varicella zoster 853: 849: 834:(pain killers), 595:local anesthetic 537:mucous membranes 455:Behçet's disease 419:immunodeficiency 262: 261: 258: 257: 254: 251: 248: 245: 158:oral candidiasis 129:; Drug-induced; 109:Emotional stress 86:Gastroenterology 62: 42: 41: 21: 4806: 4805: 4801: 4800: 4799: 4797: 4796: 4795: 4776: 4775: 4774: 4765: 4737: 4722: 4678:Ludwig's angina 4639: 4621: 4580:Mouth breathing 4566: 4545: 4366:Pneumoparotitis 4339:Frey's syndrome 4320: 4318:Salivary glands 4303: 4211: 4182: 4161:Phoenix abscess 3994: 3990:hard tissues – 3968: 3890:Hypercementosis 3809:Cementoblastoma 3795: 3758: 3472:Dens evaginatus 3426: 3396: 3348:Denture-related 3333:Plasmoacanthoma 3259:Keratoacanthoma 3080: 3078:Lining of mouth 3059: 3055:Torus palatinus 3016: 2999: 2980:Lingual thyroid 2938:Fissured tongue 2928:Crenated tongue 2904: 2887: 2873:Nasolabial cyst 2858:Herpes labialis 2812: 2799: 2794: 2751:Oral ulceration 2741: 2736: 2735: 2712: 2711: 2629: 2615: 2610: 2609: 2572: 2568: 2558: 2556: 2554: 2538: 2534: 2524: 2522: 2520: 2504: 2497: 2487: 2485: 2483: 2467: 2460: 2450: 2448: 2443: 2442: 2435: 2428: 2414: 2410: 2400: 2398: 2390: 2389: 2385: 2378: 2356: 2352: 2329: 2325: 2280: 2276: 2245: 2241: 2206:Human Pathology 2202: 2198: 2153: 2149: 2110: 2106: 2099: 2077: 2060: 2015: 2011: 1966: 1962: 1955: 1933: 1926: 1910: 1909: 1905: 1883: 1879: 1838: 1834: 1827: 1805: 1801: 1785: 1784: 1780: 1766: 1755: 1746: 1745: 1741: 1734: 1720: 1699: 1683: 1682: 1678: 1664: 1653: 1643: 1641: 1636: 1635: 1631: 1621: 1619: 1608: 1607: 1603: 1593: 1591: 1590:. A.D.A.M., Inc 1584: 1575: 1570: 1558: 1545: 1470: 1445:The conditions 1412:Behçet syndrome 1382:causes include 1368:Crohn's disease 1362:causes include 1326:causes include 1320: 1289: 1283: 1247: 1241: 1201:salivary glands 1197:maxillary sinus 1177: 1147: 1135:hyperthyroidism 1133:(e.g. used for 1107:cytotoxic drugs 1091: 963:herpes labialis 848: 814:, trauma, food 776: 750: 716:As a result of 714: 665: 663:Chemical injury 652: 625:petroleum jelly 575: 552: 529: 504:lymphadenopathy 479: 387:Crohn's disease 360: 358:Pathophysiology 348: 316:mucosal erosion 242: 238: 219: 196:mucous membrane 40: 35: 28: 23: 22: 15: 12: 11: 5: 4804: 4794: 4793: 4788: 4771: 4770: 4767: 4766: 4764: 4763: 4758: 4753: 4748: 4746:Eagle syndrome 4742: 4739: 4738: 4728: 4727: 4724: 4723: 4721: 4720: 4715: 4710: 4705: 4700: 4695: 4690: 4685: 4680: 4675: 4670: 4668:Cystic hygroma 4665: 4660: 4655: 4650: 4644: 4641: 4640: 4627: 4626: 4623: 4622: 4620: 4619: 4614: 4613: 4612: 4607: 4602: 4597: 4592: 4582: 4577: 4571: 4568: 4567: 4551: 4550: 4547: 4546: 4544: 4543: 4538: 4536:Sialolithiasis 4533: 4528: 4523: 4518: 4513: 4512: 4511: 4506: 4496: 4491: 4490: 4489: 4484: 4479: 4474: 4469: 4467:Adenocarcinoma 4464: 4456: 4451: 4446: 4441: 4436: 4434:Myoepithelioma 4431: 4426: 4421: 4416: 4403: 4398: 4393: 4388: 4383: 4378: 4373: 4368: 4363: 4362: 4361: 4351: 4346: 4341: 4336: 4331: 4325: 4322: 4321: 4309: 4308: 4305: 4304: 4302: 4301: 4300: 4299: 4294: 4284: 4279: 4278: 4277: 4272: 4267: 4262: 4257: 4252: 4247: 4242: 4232: 4227: 4222: 4216: 4213: 4212: 4188: 4187: 4184: 4183: 4181: 4180: 4175: 4170: 4165: 4164: 4163: 4153: 4148: 4143: 4142: 4141: 4136: 4131: 4121: 4116: 4111: 4110: 4109: 4107:Traumatic bone 4104: 4102:Median palatal 4099: 4094: 4086: 4081: 4076: 4071: 4066: 4061: 4056: 4040: 4035: 4030: 4025: 4020: 4015: 4010: 4005: 3999: 3996: 3995: 3974: 3973: 3970: 3969: 3967: 3966: 3961: 3956: 3955: 3954: 3949: 3944: 3934: 3929: 3924: 3919: 3914: 3913: 3912: 3902: 3897: 3895:Hypocementosis 3892: 3887: 3882: 3881: 3880: 3875: 3870: 3860: 3855: 3850: 3845: 3844: 3843: 3838: 3828: 3823: 3818: 3817: 3816: 3806: 3800: 3797: 3796: 3764: 3763: 3760: 3759: 3757: 3756: 3755: 3754: 3749: 3744: 3739: 3729: 3728: 3727: 3717: 3716: 3715: 3710: 3705: 3700: 3690: 3685: 3680: 3675: 3670: 3665: 3660: 3655: 3650: 3645: 3644: 3643: 3633: 3632: 3631: 3629:Neonatal teeth 3621: 3616: 3615: 3614: 3604: 3603: 3602: 3592: 3587: 3582: 3577: 3576: 3575: 3565: 3564: 3563: 3553: 3548: 3543: 3538: 3533: 3528: 3527: 3526: 3516: 3511: 3509:Ectopic enamel 3506: 3501: 3496: 3491: 3486: 3481: 3480: 3479: 3469: 3464: 3459: 3458: 3457: 3447: 3442: 3437: 3431: 3428: 3427: 3402: 3401: 3398: 3397: 3395: 3394: 3389: 3384: 3379: 3378: 3377: 3367: 3362: 3357: 3356: 3355: 3350: 3345: 3335: 3330: 3325: 3324: 3323: 3313: 3312: 3311: 3304:Oral melanosis 3301: 3296: 3295: 3294: 3289: 3284: 3279: 3274: 3269: 3261: 3256: 3243: 3238: 3233: 3228: 3223: 3218: 3213: 3208: 3203: 3198: 3193: 3188: 3183: 3178: 3173: 3168: 3163: 3158: 3153: 3152: 3151: 3141: 3136: 3131: 3126: 3121: 3116: 3111: 3106: 3104:Bohn's nodules 3101: 3096: 3091: 3089:Amalgam tattoo 3085: 3082: 3081: 3065: 3064: 3061: 3060: 3058: 3057: 3052: 3047: 3042: 3037: 3032: 3027: 3021: 3018: 3017: 3005: 3004: 3001: 3000: 2998: 2997: 2992: 2987: 2982: 2977: 2972: 2967: 2966: 2965: 2960: 2955: 2945: 2940: 2935: 2930: 2925: 2920: 2915: 2909: 2906: 2905: 2893: 2892: 2889: 2888: 2886: 2885: 2880: 2875: 2870: 2865: 2860: 2855: 2850: 2845: 2840: 2839: 2838: 2833: 2828: 2817: 2814: 2813: 2801: 2800: 2793: 2792: 2785: 2778: 2770: 2764: 2763: 2754: 2753:at Wikiversity 2738: 2737: 2734: 2733: 2721: 2720: 2718: 2714: 2713: 2710: 2709: 2698: 2687: 2676: 2661: 2646: 2630: 2625: 2624: 2622: 2621:Classification 2614: 2613:External links 2611: 2608: 2607: 2566: 2552: 2532: 2519:978-0323080378 2518: 2495: 2481: 2458: 2433: 2427:978-1455702626 2426: 2408: 2383: 2376: 2350: 2339:(10): 485–92. 2323: 2274: 2239: 2196: 2147: 2104: 2097: 2058: 2009: 1960: 1953: 1924: 1903: 1877: 1832: 1825: 1799: 1778: 1753: 1748:"Mouth ulcers" 1739: 1732: 1697: 1676: 1651: 1629: 1601: 1572: 1571: 1569: 1566: 1565: 1564: 1557: 1554: 1544: 1541: 1540: 1539: 1532: 1529: 1526: 1515: 1512: 1505: 1496:and use of an 1490: 1484: 1481: 1469: 1466: 1404:Sweet syndrome 1380:Dermatological 1364:celiac disease 1334:deficiencies, 1319: 1316: 1297:Balsam of Peru 1285:Main article: 1282: 1279: 1243:Main article: 1240: 1237: 1173:Main article: 1146: 1143: 1099:bisphosphonate 1090: 1087: 1042:cryptococcosis 959:herpes simplex 953: 952: 947: 941: 940: 934:histoplasmosis 930:cryptococcosis 923: 917: 916: 899: 893: 892: 867: 861: 860: 857: 847: 844: 781:floor of mouth 772:Main article: 758:aphthous ulcer 749: 746: 713: 710: 693:Silver nitrate 685:chlorpromazine 664: 661: 651: 648: 632:lingual frenum 574: 571: 551: 548: 528: 525: 514:(diabetes). A 488:oral physician 478: 475: 423:immunoglobulin 359: 356: 352:adverse effect 347: 344: 312:lamina propria 299:lamina propria 218: 215: 174: 173: 146: 142: 141: 119: 113: 112: 105:herpes viruses 97: 93: 92: 83: 77: 76: 64: 63: 55: 54: 51: 47: 46: 38: 26: 9: 6: 4: 3: 2: 4803: 4792: 4789: 4787: 4784: 4783: 4781: 4762: 4759: 4757: 4754: 4752: 4749: 4747: 4744: 4743: 4740: 4733: 4729: 4719: 4716: 4714: 4711: 4709: 4706: 4704: 4701: 4699: 4696: 4694: 4691: 4689: 4686: 4684: 4681: 4679: 4676: 4674: 4671: 4669: 4666: 4664: 4661: 4659: 4656: 4654: 4651: 4649: 4648:Actinomycosis 4646: 4645: 4642: 4638: 4632: 4628: 4618: 4615: 4611: 4608: 4606: 4603: 4601: 4598: 4596: 4593: 4591: 4588: 4587: 4586: 4583: 4581: 4578: 4576: 4573: 4572: 4569: 4565: 4561: 4556: 4552: 4542: 4539: 4537: 4534: 4532: 4529: 4527: 4526:Sialodochitis 4524: 4522: 4519: 4517: 4514: 4510: 4507: 4505: 4502: 4501: 4500: 4497: 4495: 4492: 4488: 4485: 4483: 4480: 4478: 4475: 4473: 4470: 4468: 4465: 4463: 4460: 4457: 4455: 4452: 4450: 4447: 4445: 4442: 4440: 4437: 4435: 4432: 4430: 4427: 4425: 4422: 4420: 4417: 4415: 4412: 4409: 4408: 4407: 4404: 4402: 4399: 4397: 4394: 4392: 4389: 4387: 4384: 4382: 4379: 4377: 4374: 4372: 4369: 4367: 4364: 4360: 4357: 4356: 4355: 4352: 4350: 4347: 4345: 4342: 4340: 4337: 4335: 4332: 4330: 4327: 4326: 4323: 4319: 4314: 4310: 4298: 4295: 4293: 4290: 4289: 4288: 4285: 4283: 4280: 4276: 4273: 4271: 4268: 4266: 4263: 4261: 4258: 4256: 4253: 4251: 4248: 4246: 4243: 4241: 4238: 4237: 4236: 4233: 4231: 4228: 4226: 4223: 4221: 4218: 4217: 4214: 4210: 4206: 4205:malocclusions 4202: 4198: 4193: 4189: 4179: 4176: 4174: 4173:Stafne defect 4171: 4169: 4166: 4162: 4159: 4158: 4157: 4154: 4152: 4149: 4147: 4144: 4140: 4137: 4135: 4132: 4130: 4127: 4126: 4125: 4124:Osteonecrosis 4122: 4120: 4119:Osteomyelitis 4117: 4115: 4112: 4108: 4105: 4103: 4100: 4098: 4095: 4093: 4090: 4087: 4085: 4082: 4080: 4077: 4075: 4072: 4070: 4067: 4065: 4062: 4060: 4057: 4055: 4052: 4050: 4046: 4045: 4044: 4041: 4039: 4036: 4034: 4031: 4029: 4026: 4024: 4021: 4019: 4016: 4014: 4011: 4009: 4006: 4004: 4001: 4000: 3997: 3993: 3992:Bones of jaws 3989: 3985: 3979: 3975: 3965: 3962: 3960: 3957: 3953: 3950: 3948: 3945: 3943: 3940: 3939: 3938: 3937:Periodontitis 3935: 3933: 3930: 3928: 3925: 3923: 3920: 3918: 3917:Pericoronitis 3915: 3911: 3908: 3907: 3906: 3903: 3901: 3898: 3896: 3893: 3891: 3888: 3886: 3883: 3879: 3876: 3874: 3873:Granulomatous 3871: 3869: 3866: 3865: 3864: 3861: 3859: 3856: 3854: 3851: 3849: 3846: 3842: 3839: 3837: 3834: 3833: 3832: 3829: 3827: 3826:Eruption cyst 3824: 3822: 3819: 3815: 3812: 3811: 3810: 3807: 3805: 3802: 3801: 3798: 3794: 3790: 3786: 3782: 3778: 3774: 3769: 3765: 3753: 3750: 3748: 3745: 3743: 3740: 3738: 3735: 3734: 3733: 3730: 3726: 3723: 3722: 3721: 3718: 3714: 3711: 3709: 3706: 3704: 3701: 3699: 3696: 3695: 3694: 3691: 3689: 3686: 3684: 3681: 3679: 3676: 3674: 3671: 3669: 3666: 3664: 3661: 3659: 3656: 3654: 3653:Pulp necrosis 3651: 3649: 3646: 3642: 3639: 3638: 3637: 3634: 3630: 3627: 3626: 3625: 3622: 3620: 3617: 3613: 3612:Dens in dente 3610: 3609: 3608: 3605: 3601: 3598: 3597: 3596: 3593: 3591: 3588: 3586: 3583: 3581: 3578: 3574: 3571: 3570: 3569: 3566: 3562: 3559: 3558: 3557: 3554: 3552: 3549: 3547: 3544: 3542: 3539: 3537: 3534: 3532: 3529: 3525: 3522: 3521: 3520: 3517: 3515: 3512: 3510: 3507: 3505: 3504:Discoloration 3502: 3500: 3497: 3495: 3492: 3490: 3487: 3485: 3482: 3478: 3475: 3474: 3473: 3470: 3468: 3465: 3463: 3460: 3456: 3453: 3452: 3451: 3448: 3446: 3443: 3441: 3438: 3436: 3433: 3432: 3429: 3424: 3420: 3416: 3412: 3407: 3403: 3393: 3390: 3388: 3385: 3383: 3380: 3376: 3373: 3372: 3371: 3368: 3366: 3363: 3361: 3358: 3354: 3351: 3349: 3346: 3344: 3341: 3340: 3339: 3336: 3334: 3331: 3329: 3326: 3322: 3319: 3318: 3317: 3314: 3310: 3307: 3306: 3305: 3302: 3300: 3297: 3293: 3290: 3288: 3285: 3283: 3280: 3278: 3275: 3273: 3270: 3268: 3265: 3262: 3260: 3257: 3255: 3252: 3249: 3248: 3247: 3244: 3242: 3239: 3237: 3234: 3232: 3229: 3227: 3224: 3222: 3219: 3217: 3214: 3212: 3211:Lichen planus 3209: 3207: 3204: 3202: 3199: 3197: 3194: 3192: 3189: 3187: 3186:Herpes zoster 3184: 3182: 3179: 3177: 3174: 3172: 3169: 3167: 3164: 3162: 3161:Fordyce spots 3159: 3157: 3154: 3150: 3147: 3146: 3145: 3142: 3140: 3139:Erythroplakia 3137: 3135: 3132: 3130: 3127: 3125: 3122: 3120: 3117: 3115: 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3095: 3092: 3090: 3087: 3086: 3083: 3079: 3075: 3070: 3066: 3056: 3053: 3051: 3048: 3046: 3043: 3041: 3038: 3036: 3033: 3031: 3028: 3026: 3023: 3022: 3019: 3015: 3010: 3006: 2996: 2993: 2991: 2988: 2986: 2983: 2981: 2978: 2976: 2973: 2971: 2968: 2964: 2961: 2959: 2956: 2954: 2951: 2950: 2949: 2946: 2944: 2941: 2939: 2936: 2934: 2931: 2929: 2926: 2924: 2923:Caviar tongue 2921: 2919: 2916: 2914: 2913:Ankyloglossia 2911: 2910: 2907: 2903: 2898: 2894: 2884: 2881: 2879: 2878:Sun poisoning 2876: 2874: 2871: 2869: 2866: 2864: 2861: 2859: 2856: 2854: 2851: 2849: 2846: 2844: 2841: 2837: 2834: 2832: 2829: 2827: 2824: 2823: 2822: 2819: 2818: 2815: 2811: 2806: 2802: 2798: 2791: 2786: 2784: 2779: 2777: 2772: 2771: 2768: 2762: 2758: 2755: 2752: 2747: 2743: 2742: 2732: 2728: 2727: 2723: 2722: 2719: 2715: 2708: 2704: 2703: 2699: 2697: 2693: 2692: 2688: 2686: 2682: 2681: 2677: 2675: 2671: 2670: 2666: 2662: 2660: 2656: 2655: 2651: 2647: 2645: 2641: 2640: 2636: 2632: 2631: 2628: 2623: 2619: 2603: 2599: 2594: 2589: 2585: 2581: 2577: 2570: 2555: 2553:9780323225724 2549: 2545: 2544: 2536: 2521: 2515: 2511: 2510: 2502: 2500: 2484: 2482:9783540777823 2478: 2474: 2473: 2465: 2463: 2446: 2440: 2438: 2429: 2423: 2419: 2412: 2397: 2393: 2387: 2379: 2373: 2369: 2364: 2363: 2354: 2346: 2342: 2338: 2334: 2327: 2319: 2315: 2310: 2305: 2301: 2297: 2293: 2289: 2285: 2278: 2270: 2266: 2262: 2258: 2255:(4): 830–36. 2254: 2250: 2243: 2235: 2231: 2227: 2223: 2219: 2215: 2211: 2207: 2200: 2192: 2188: 2183: 2178: 2174: 2170: 2167:(2): 98–110. 2166: 2162: 2158: 2151: 2143: 2139: 2135: 2131: 2127: 2123: 2120:(3): 285–86. 2119: 2115: 2108: 2100: 2094: 2090: 2085: 2084: 2075: 2073: 2071: 2069: 2067: 2065: 2063: 2054: 2050: 2045: 2040: 2036: 2032: 2028: 2024: 2020: 2013: 2005: 2001: 1996: 1991: 1987: 1983: 1979: 1975: 1971: 1964: 1956: 1950: 1946: 1941: 1940: 1931: 1929: 1920: 1914: 1906: 1900: 1896: 1891: 1890: 1881: 1873: 1869: 1864: 1859: 1856:(2): 135–42. 1855: 1851: 1847: 1843: 1836: 1828: 1822: 1818: 1813: 1812: 1803: 1795: 1789: 1781: 1775: 1771: 1764: 1762: 1760: 1758: 1749: 1743: 1735: 1729: 1725: 1718: 1716: 1714: 1712: 1710: 1708: 1706: 1704: 1702: 1693: 1687: 1679: 1673: 1669: 1662: 1660: 1658: 1656: 1639: 1633: 1618:(Online). n.d 1617: 1616: 1611: 1605: 1589: 1582: 1580: 1578: 1573: 1563: 1560: 1559: 1553: 1551: 1537: 1533: 1530: 1527: 1524: 1520: 1516: 1513: 1510: 1506: 1503: 1502:chlorhexidine 1499: 1495: 1491: 1489: 1485: 1482: 1479: 1478: 1477: 1475: 1465: 1462: 1458: 1454: 1452: 1448: 1443: 1441: 1437: 1433: 1429: 1425: 1421: 1417: 1413: 1409: 1405: 1401: 1397: 1396:lichen planus 1393: 1389: 1385: 1381: 1377: 1373: 1369: 1365: 1361: 1357: 1353: 1349: 1345: 1341: 1337: 1333: 1329: 1325: 1324:Hematological 1315: 1313: 1310: 1309:oropharyngeal 1306: 1302: 1298: 1294: 1288: 1278: 1276: 1272: 1268: 1264: 1260: 1256: 1252: 1246: 1236: 1234: 1230: 1229:erythroplasia 1224: 1222: 1218: 1214: 1210: 1206: 1202: 1198: 1194: 1190: 1186: 1182: 1176: 1168: 1164: 1160: 1156: 1151: 1142: 1140: 1136: 1132: 1128: 1124: 1120: 1116: 1112: 1108: 1104: 1100: 1096: 1086: 1084: 1080: 1076: 1072: 1068: 1064: 1061: 1057: 1053: 1052:Blastomycosis 1049: 1048: 1043: 1039: 1035: 1031: 1027: 1023: 1019: 1014: 1012: 1008: 1007: 1002: 998: 997: 992: 988: 984: 980: 976: 972: 968: 964: 960: 951: 950:leishmaniasis 948: 946: 943: 942: 939: 935: 931: 927: 926:blastomycosis 924: 922: 919: 918: 915: 911: 907: 903: 900: 898: 895: 894: 891: 887: 883: 879: 875: 871: 868: 866: 863: 862: 858: 855: 854: 843: 841: 837: 833: 829: 825: 821: 817: 813: 809: 805: 801: 797: 793: 788: 786: 782: 775: 767: 763: 762:labial mucosa 759: 754: 745: 743: 739: 735: 731: 727: 723: 719: 709: 707: 703: 698: 694: 690: 686: 682: 677: 675: 671: 660: 659:destruction. 656: 647: 645: 641: 637: 633: 628: 626: 622: 617: 615: 611: 607: 603: 598: 596: 592: 584: 579: 570: 568: 561: 560:labial mucosa 556: 547: 544: 542: 538: 534: 524: 521: 517: 513: 507: 505: 499: 497: 493: 489: 485: 474: 472: 468: 464: 461:in the eyes. 460: 456: 452: 448: 444: 440: 436: 435:mononucleosis 432: 428: 424: 420: 416: 412: 407: 404: 398: 396: 390: 388: 384: 378: 376: 372: 368: 363: 355: 353: 343: 341: 337: 333: 332: 327: 325: 321: 317: 313: 309: 308: 302: 300: 296: 292: 288: 283: 281: 280:mucosal ulcer 277: 273: 269: 266: 260: 231: 223: 214: 212: 207: 205: 201: 197: 193: 189: 185: 181: 172: 171:levonordefrin 168: 164: 159: 155: 151: 147: 143: 140: 136: 132: 128: 124: 120: 118: 114: 110: 106: 102: 98: 94: 91: 90:Oral medicine 87: 84: 82: 78: 74: 73:labial mucosa 70: 65: 61: 56: 52: 48: 43: 37: 33: 19: 4636: 4563: 4499:Sialadenitis 4458: 4410: 4275:Scissor bite 4270:Retrognathia 4255:Overeruption 4235:Malocclusion 4208: 4088: 4047: 4038:Micrognathia 3991: 3982:Periapical, 3868:Desquamative 3792: 3773:Periodontium 3747:Acid erosion 3688:Taurodontism 3619:Open contact 3531:Enamel pearl 3499:Dilaceration 3462:Concrescence 3369: 3263: 3250: 3077: 3030:Cleft palate 2990:Microglossia 2985:Macroglossia 2970:Glossoptosis 2868:Microcheilia 2863:Macrocheilia 2724: 2700: 2689: 2678: 2663: 2648: 2633: 2583: 2579: 2569: 2557:. Retrieved 2542: 2535: 2523:. Retrieved 2508: 2486:. Retrieved 2475:. Springer. 2471: 2449:. Retrieved 2417: 2411: 2399:. Retrieved 2395: 2386: 2361: 2353: 2336: 2332: 2326: 2291: 2287: 2277: 2252: 2248: 2242: 2209: 2205: 2199: 2164: 2160: 2150: 2117: 2113: 2107: 2082: 2026: 2022: 2012: 1977: 1973: 1963: 1938: 1888: 1880: 1853: 1849: 1835: 1810: 1802: 1769: 1742: 1723: 1667: 1642:. Retrieved 1632: 1620:. Retrieved 1613: 1604: 1592:. Retrieved 1546: 1543:Epidemiology 1494:oral hygiene 1471: 1457:Macroglossia 1455: 1444: 1356:gammopathies 1321: 1318:Other causes 1290: 1248: 1225: 1205:nasal cavity 1178: 1163:premalignant 1115:chemotherapy 1111:methotrexate 1103:osteoporosis 1092: 1089:Drug-induced 1045: 1037: 1034:valley fever 1029: 1025: 1021: 1017: 1015: 1004: 1001:tuberculosis 994: 956: 914:tuberculosis 812:menstruation 794:deficiency ( 789: 777: 766:erythematous 718:radiotherapy 715: 678: 666: 657: 653: 629: 618: 599: 588: 564: 545: 530: 508: 500: 492:oral surgeon 480: 451:desquamation 439:Autoimmunity 427:Chemotherapy 399: 391: 379: 371:radiotherapy 364: 361: 349: 329: 328: 315: 305: 303: 284: 279: 267: 236: 208: 187: 183: 179: 177: 36: 4693:Microstomia 4683:Macrostomia 4673:Gnathophyma 4590:Catathrenia 4585:Sleep apnea 4516:Sialectasis 4059:Dentigerous 4049:Odontogenic 3878:Plasma cell 3814:Gigantiform 3590:Microdontia 3580:Macrodontia 3551:Hyperdontia 3246:Oral cancer 3206:Leukoplakia 3114:Candidiasis 3074:Oral mucosa 2995:Rhabdomyoma 2975:Hypoglossia 2836:Plasma cell 2757:Mouth ulcer 2726:MedlinePlus 2586:(1): 9–16. 2401:11 December 2029:(1): 1–11. 1842:Ben-Horin S 1644:27 December 1594:27 December 1536:vitamin B12 1509:benzydamine 1474:symptomatic 1436:sarcoidosis 1432:glucagonoma 1336:neutropenia 1175:Oral cancer 1167:glossectomy 1155:oral cancer 1095:alendronate 1026:Bacteroides 1022:Actinomyces 975:chicken pox 859:Example(s) 836:antiseptics 712:Irradiation 702:endodontics 614:child abuse 541:oral cavity 331:Excoriation 204:oral cancer 200:oral cavity 188:Cancer sore 180:mouth ulcer 163:vitamin B12 50:Other names 45:Mouth ulcer 32:Canker sore 4780:Categories 4653:Angioedema 4459:Malignant: 4439:Oncocytoma 4265:Prognathia 4054:periapical 4033:Microgenia 3984:mandibular 3942:Aggressive 3863:Gingivitis 3804:Cementicle 3742:Abfraction 3732:Tooth wear 3725:Edentulism 3720:Tooth loss 3673:Resorption 3658:Pulp polyp 3641:Pulp stone 3585:Meth mouth 3556:Hypodontia 3546:Gemination 3477:Talon cusp 3370:Ulceration 3338:Stomatitis 3316:Pemphigoid 3264:Malignant: 3216:Linea alba 3201:Leukoedema 3181:Herpangina 3149:Giant-cell 2691:DiseasesDB 2294:(7): e38. 1568:References 1519:antifungal 1498:antiseptic 1352:dyscrasias 1301:stomatitis 1185:carcinomas 1145:Malignancy 1123:nicorandil 1085:and skin. 878:herpangina 870:chickenpox 832:analgesics 824:toothpaste 734:osteocytes 726:xerostomia 722:stomatitis 706:rubber dam 606:factitious 573:Mechanical 512:urinalysis 375:Stomatitis 367:xerostomia 295:periosteum 237:An ulcer ( 217:Definition 167:benzocaine 154:antifungal 131:Malignancy 18:Oral ulcer 4521:Sialocele 4504:Parotitis 4245:Open bite 4240:Crossbite 4018:Cherubism 3988:maxillary 3821:Cementoma 3752:Attrition 3568:Impaction 3536:Fluorosis 3445:Anodontia 3440:Ankylosis 3328:Pemphigus 2948:Glossitis 2843:Cleft lip 2821:Cheilitis 2702:SNOMED CT 2212:: 18–41. 2142:204986006 1913:cite book 1840:Zbar AP, 1788:cite book 1686:cite book 1468:Treatment 1332:hematinic 1305:cheilitis 1233:indurated 1189:lymphomas 1181:cancerous 1153:Advanced 1063:protozoan 1060:parasitic 1018:Neisseria 945:Parasitic 897:Bacterial 846:Infection 816:allergies 800:vitamin B 792:hematinic 621:abrasions 602:self-harm 477:Diagnosis 463:Vitamin C 449:, causes 415:keratotic 403:fibrinous 395:mucositis 340:capillary 336:rete pegs 320:epidermis 291:submucosa 145:Treatment 127:Infection 81:Specialty 71:) on the 4531:Sialosis 4482:Lymphoma 4354:Mucocele 4250:Overbite 4003:Agnathia 3964:Teething 3789:alveolus 3785:cementum 3737:Abrasion 3713:Occlusal 3698:Avulsion 3663:Pulpitis 3607:Odontoma 3353:Herpetic 3343:Aphthous 2853:Eclabium 2707:26284000 2602:19124628 2345:10726452 2318:15201264 2269:21816532 2234:47010934 2226:29885408 2191:21498973 2134:26307375 2053:19210521 2004:10894697 1872:22325167 1556:See also 1428:diabetes 1344:leukemia 1293:allergen 1193:sarcomas 1159:T4 N2 M0 1011:syphilis 979:shingles 910:syphilis 828:steroids 742:mandible 674:pulpitis 272:necrosis 190:, is an 4617:Snoring 4575:Bruxism 4411:Benign: 4260:Overjet 4220:Bruxism 4114:Osteoma 3952:Chronic 3777:gingiva 3251:Benign: 3144:Fibroma 2831:Angular 2826:Actinic 2685:D019226 2644:DA01.15 2559:6 March 2525:6 March 2488:5 March 2451:5 March 2309:1768343 2182:3134932 2044:2673735 1995:1118165 1622:19 July 1610:"ulcer" 1374:), and 1281:Allergy 1217:alcohol 1213:smoking 1139:cocaine 1113:, i.e. 1044:), and 981:), and 961:virus ( 760:on the 730:atrophy 681:eugenol 670:aspirin 539:of the 523:occur. 484:dentist 459:uveitis 406:exudate 342:loops. 307:erosion 263:; from 198:of the 139:Allergy 4359:Ranula 3831:Epulis 3693:Trauma 3541:Fusion 3450:Caries 3423:enamel 3419:dentin 3014:Palate 2902:Tongue 2761:Curlie 2731:001448 2600:  2550:  2516:  2479:  2424:  2374:  2343:  2316:  2306:  2267:  2232:  2224:  2189:  2179:  2140:  2132:  2095:  2051:  2041:  2002:  1992:  1951:  1901:  1870:  1823:  1776:  1730:  1674:  1354:, and 1328:anemia 1312:mucosa 1273:, and 1187:, but 1129:) and 1127:angina 1109:(e.g. 1003:) and 921:Fungal 808:stress 796:folate 764:(note 697:Phenol 583:frenum 516:biopsy 467:scurvy 433:, and 385:/oral 346:Causes 184:aphtha 96:Causes 4736:Other 3411:Teeth 2696:22751 2674:528.9 2288:Heart 2230:S2CID 2138:S2CID 2091:–84. 1945:Mosby 1897:–79. 1819:–91. 1223:use. 1221:betel 1067:cysts 865:Viral 856:Agent 494:, or 411:edema 268:ulcus 265:Latin 192:ulcer 4698:Noma 4203:and 3986:and 3791:) – 3415:pulp 2810:Lips 2680:MeSH 2669:9-CM 2598:PMID 2561:2014 2548:ISBN 2527:2014 2514:ISBN 2490:2014 2477:ISBN 2453:2014 2422:ISBN 2403:2018 2396:NICE 2372:ISBN 2341:PMID 2314:PMID 2265:PMID 2222:PMID 2187:PMID 2130:PMID 2093:ISBN 2049:PMID 2000:PMID 1949:ISBN 1919:link 1899:ISBN 1868:PMID 1821:ISBN 1794:link 1774:ISBN 1728:ISBN 1692:link 1672:ISBN 1646:2012 1624:2015 1596:2012 1449:and 1438:and 1394:and 1303:and 1215:and 1058:, a 1054:"). 804:iron 683:and 630:The 314:. 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Index

Oral ulcer
Canker sore

aphthous stomatitis
labial mucosa
Specialty
Gastroenterology
Oral medicine
SLS
herpes viruses
Emotional stress
Diagnostic method
Aphthous stomatitis
Infection
Malignancy
Vesiculobullous disease
Allergy
SLS-free toothpaste
antifungal
oral candidiasis
vitamin B12
benzocaine
levonordefrin
ulcer
mucous membrane
oral cavity
oral cancer
aphthous stomatitis

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